Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pknBProbable serine/threonine-protein kinase pknB; Best DB hits: BLAST: swissprot:P54744; PKNB_MYCLE PUTATIVE SERINETHREONINE-PROTEIN; E=9e-38 pir:H69878; probable protein kinase (EC 2.7.1.-) yloP - Bacillus; E=3e-37 ddbj:BAB06223.1; (AP001515) serinethreonine protein kinase; E=7e-37 COG: BS_yloP_1; COG0515 Serine/threonine protein kinases; E=2e-38 PFAM: PF00069; Protein kinase domain; E=2.1e-52. (766 aa)    
Predicted Functional Partners:
Pph1
Probable protein phosphatase 1; PMID: 11298281 best DB hits: BLAST: gb:AAF81068.1; AF223364_3 (AF223364) protein phosphatase 1; E=9e-32 pir:E71538; hypothetical protein CT259 - Chlamydia trachomatis; E=4e-28 pir:H75265; conserved hypothetical protein - Deinococcus radiodurans; E=5e-28 COG: CT259; COG0631 Protein serine/threonine phosphatases; E=4e-29 PFAM: PF00481; Protein phosphatase 2C; E=4.9e-09.
 
   0.804
RB3245
Protein phosphatase 1; PMID: 11298281 best DB hits: BLAST: gb:AAF81068.1; AF223364_3 (AF223364) protein phosphatase 1; E=3e-27 pir:E71538; hypothetical protein CT259 - Chlamydia trachomatis; E=5e-26 embl:CAA10712.1; (AJ132604) pppL protein [Lactococcus lactis]; E=2e-25 COG: CT259; COG0631 Protein serine/threonine phosphatases; E=4e-27 PFAM: PF00481; Protein phosphatase 2C; E=1.2e-09.
 
   0.803
rpoE
Probable RNA polymerase sigma-E factor; PMID: 7768826 PMID: 7889934 PMID: 7889935 best DB hits: BLAST: pir:H82073; RNA polymerase sigma-E factor VC2467 [imported] - Vibrio; E=1e-05 swissprot:P44790; RPOE_HAEIN RNA POLYMERASE SIGMA-E FACTOR; E=9e-05 pir:C82583; RNA polymerase sigma-H factor XF2239 [imported] -; E=3e-04 COG: VC2467; COG1595 DNA-directed RNA polymerase specialized sigma; E=1e-06 PFAM: PF00776; Sigma-70 factor (ECF subfamily); E=0.0054 PF00140; Sigma-70 factor; E=2.7e-05.
   
   0.777
RB6417
Conserved hypothetical protein-putative FHA domain; PMID: 9634230 PMID: 7482699 best DB hits: BLAST: pir:B70700; hypothetical protein Rv0020c - Mycobacterium; E=8e-06 pir:T10015; hypothetical protein MLB1770.15c - Mycobacterium leprae; E=4e-05 ddbj:BAB20624.1; (AB052847) adenylate cyclase; E=0.001 COG: Rv0020c_2; COG1716 FHA-domain-containing proteins; E=4e-06 PFAM: PF00498; FHA domain; E=8.9e-17.
  
 
 
 0.723
RB2671
Conserved hypothetical protein; PMID: 7482699 best DB hits: BLAST: ddbj:BAA91718.1; (AK001486) unnamed protein product [Homo; E=0.007 ddbj:BAB08640.1; (AB009048) gene_id:K15E6.5~unknown protein; E=0.012 pir:T00095; hypothetical protein KIAA0470 - human ----- ddbj:; E=0.052 PFAM: PF00498; FHA domain; E=1.8e-12.
    
 
 0.650
uspA-2
Conserved hypothetical protein; PMID: 9371463 best DB hits: BLAST: pir:A69220; conserved hypothetical protein MTH898 - Methanobacterium; E=1e-07 gb:AAD46412.1; AF096262_1 (AF096262) ER6 protein [Lycopersicon; E=1e-05 gb:AAK04173.1; AE006246_3 (AE006246) conserved hypothetical; E=2e-05 COG: MTH898; COG0589 Universal stress protein UspA and related; E=1e-08 PFAM: PF00582; Universal stress protein family; E=4e-11.
  
  
 0.641
RB8026
Best DB hits: BLAST: pir:E82768; conserved hypothetical protein XF0752 [imported] -; E=4e-30 pir:A82381; conserved hypothetical protein VCA1077 [imported] -; E=1e-26 gb:AAF47337.1; (AE003467) CG7049 gene product [Drosophila; E=5e-19 COG: XF0752_2; COG1262 Uncharacterized BCR; E=9e-30.
 
 
  
 0.634
RB11998
Conserved hypothetical protein-putative transcriptional regulator; Best DB hits: BLAST: pir:E82768; conserved hypothetical protein XF0752 [imported] -; E=3e-13 pir:A82381; conserved hypothetical protein VCA1077 [imported] -; E=1e-10 pir:E83347; hypothetical protein PA2395 [imported] - Pseudomonas; E=4e-10 COG: XF0752_2; COG1262 Uncharacterized BCR; E=1e-13.
   
  
 0.627
mesJ
Cell cycle protein homolog mesJ; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family.
     
 0.622
RB1789
PMID: 10484179 best DB hits: BLAST: ddbj:BAB05496.1; (AP001513) BH1777~unknown conserved protein; E=1e-04 ddbj:BAA14001.1; (D89626) adenylate cyclase [Anabaena sp.]; E=0.001 pir:B70700; hypothetical protein Rv0020c - Mycobacterium; E=0.003 COG: BH1777_1; COG1716 FHA-domain-containing proteins; E=5e-05 PFAM: PF00498; FHA domain; E=4.6e-18.
  
 
 
 0.616
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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