STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pknHBest DB hits: BLAST: swissprot:Q11053; PKNH_MYCTU PROBABLE SERINETHREONINE-PROTEIN; E=3e-35 embl:CAB94054.1; (AL358672) putative serinethreonine-protein; E=1e-34 embl:CAA10713.1; (AJ132604) hypothetical protein [Lactococcus; E=2e-33 COG: Rv1266c; COG0515 Serine/threonine protein kinases; E=3e-36 PFAM: PF00069; Protein kinase domain; E=7.6e-54. (364 aa)    
Predicted Functional Partners:
Pph1
Probable protein phosphatase 1; PMID: 11298281 best DB hits: BLAST: gb:AAF81068.1; AF223364_3 (AF223364) protein phosphatase 1; E=9e-32 pir:E71538; hypothetical protein CT259 - Chlamydia trachomatis; E=4e-28 pir:H75265; conserved hypothetical protein - Deinococcus radiodurans; E=5e-28 COG: CT259; COG0631 Protein serine/threonine phosphatases; E=4e-29 PFAM: PF00481; Protein phosphatase 2C; E=4.9e-09.
 
   0.801
RB3245
Protein phosphatase 1; PMID: 11298281 best DB hits: BLAST: gb:AAF81068.1; AF223364_3 (AF223364) protein phosphatase 1; E=3e-27 pir:E71538; hypothetical protein CT259 - Chlamydia trachomatis; E=5e-26 embl:CAA10712.1; (AJ132604) pppL protein [Lactococcus lactis]; E=2e-25 COG: CT259; COG0631 Protein serine/threonine phosphatases; E=4e-27 PFAM: PF00481; Protein phosphatase 2C; E=1.2e-09.
  
   0.800
rplU
50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
  
    0.721
RB10135
Hypothetical protein.
       0.718
RB10136
Hypothetical protein.
       0.534
RB8026
Best DB hits: BLAST: pir:E82768; conserved hypothetical protein XF0752 [imported] -; E=4e-30 pir:A82381; conserved hypothetical protein VCA1077 [imported] -; E=1e-26 gb:AAF47337.1; (AE003467) CG7049 gene product [Drosophila; E=5e-19 COG: XF0752_2; COG1262 Uncharacterized BCR; E=9e-30.
 
 
  
 0.514
pknB-10
Serine/threonine protein kinase; Best DB hits: BLAST: ddbj:BAB06223.1; (AP001515) serinethreonine protein kinase; E=1e-33 swissprot:P71584; PKNB_MYCTU PUTATIVE SERINETHREONINE-PROTEIN; E=1e-32 pir:H69878; probable protein kinase (EC 2.7.1.-) yloP - Bacillus; E=1e-32 COG: BH2504_1; COG0515 Serine/threonine protein kinases; E=1e-34 PFAM: PF00069; Protein kinase domain; E=2.6e-53.
  
   
0.462
pknB-2
Probable serine/threonine-protein kinase pknB; PMID: 835671 best DB hits: BLAST: swissprot:P54744; PKNB_MYCLE PUTATIVE SERINETHREONINE-PROTEIN; E=3e-34 swissprot:P71584; PKNB_MYCTU PUTATIVE SERINETHREONINE-PROTEIN; E=5e-33 pir:T36717; probable serinethreonine protein kinase - Streptomyces; E=9e-32 COG: Rv0014c_1; COG0515 Serine/threonine protein kinases; E=5e-34 PFAM: PF00069; Protein kinase domain; E=1.3e-46 PF00400; WD domain, G-beta repeat; E=0.00029.
  
   
0.461
pknB-4
Probable serine/threonine-protein kinase; PMID: 8969512 best DB hits: BLAST: embl:CAA18685.1; (AL022602) putative serinethreonine protein; E=3e-23 pir:B70936; probable serinethreonine-specific protein kinase (EC; E=2e-22 swissprot:P54744; PKNB_MYCLE PUTATIVE SERINETHREONINE-PROTEIN; E=6e-22 COG: Rv2176; COG0515 Serine/threonine protein kinases; E=2e-23 PFAM: PF00069; Protein kinase domain; E=9.4e-41.
  
   
0.461
pknB-8
Probable serine/threonine-protein kinase pknB; PMID: 1835671 best DB hits: BLAST: swissprot:P54744; PKNB_MYCLE PUTATIVE SERINETHREONINE-PROTEIN; E=2e-35 pir:T36501; probable serinethreonine protein kinase - Streptomyces; E=2e-34 embl:CAB94054.1; (AL358672) putative serinethreonine-protein; E=4e-34 COG: Rv0014c_1; COG0515 Serine/threonine protein kinases; E=2e-33 PFAM: PF00069; Protein kinase domain; E=3e-52 PF00191; Annexin; E=0.78.
  
   
0.454
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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