STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
rnHRibonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (158 aa)    
Predicted Functional Partners:
rnhA
Probable ribonuclease HI; PMID: 1650910 best DB hits: BLAST: pir:A83418; ribonuclease H PA1815 [imported] - Pseudomonas; E=1e-04 pdb:1RBR; Ribonuclease H (E.C.3.1.26.4) Mutant With His 62; E=2e-04 swissprot:P23329; RNH_SALTY RIBONUCLEASE HI (RNASE HI); E=5e-04 COG: PA1815; COG0328 Ribonuclease HI; E=1e-05.
  
  
 
0.906
deoC
Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
 
      0.831
RB2928
Conserved hypothetical protein-putative acetyltransferase; PMID: 8892832 best DB hits: BLAST: gb:AAC44553.1; (U34346) unknown [Paracoccus denitrificans]; E=6e-33 embl:CAB61920.1; (AL133278) putative acetyltransferase; E=3e-28 swissprot:Q09927; YAL4_SCHPO HYPOTHETICAL 23.8 KD PROTEIN; E=6e-16 COG: BH2104; COG0456 Acetyltransferases; E=0.007 PFAM: PF00583; Acetyltransferase (GNAT) family; E=2.2e-16.
 
      0.706
ssb
Single-strand binding protein; PMID: 6270666 PMID: 6384214 best DB hits: BLAST: swissprot:O83101; SSB_TREPA SINGLE-STRAND BINDING PROTEIN (SSB); E=7e-23 embl:CAA76674.1; (Y17166) single strand DNA binding protein; E=1e-19 pir:B81310; single-strand DNA binding protein Cj1071 [imported] -; E=1e-19 COG: TP0062; COG0629 Single-stranded DNA-binding protein; E=7e-24 PFAM: PF00436; Single-strand binding protein family; E=1.7e-48.
   
 0.542
dnaX
DNA polymerase III gamma and tau subunits; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
  
 
 0.537
RB10272
Pteridine reductase 1-possibly short-chain dehydrogenase; Best DB hits: BLAST: pir:B82680; pteridine reductase 1 XF1457 [imported] - Xylella; E=4e-27 swissprot:P50161; VER1_ASPPA VERSICOLORIN REDUCTASE (VER-1); E=8e-23 swissprot:Q08632; SDR1_PICAB SHORT-CHAIN TYPE; E=9e-22 COG: XF1457; COG1028 Dehydrogenases with different specificities (related; E=4e-28 PAB1085; COG1028 Dehydrogenases with different specificities; E=1e-20 BH1511; COG1028 Dehydrogenases with different specificities (related; E=2e-19 PFAM: PF00106; short chain dehydrogenase; E=3.1e-32 PF00678; Short chain dehydrogenase/ [...]
  
    0.528
crtI
Phytoene dehydrogenase; PMID: 8467787 PMID: 7588751 PMID: 8021167 best DB hits: BLAST: pir:S43324; zeta-carotene desaturase - Anabaena sp. (strain PCC; E=2e-82 swissprot:Q02861; CRTI_MYXXA PHYTOENE DEHYDROGENASE (PHYTOENE; E=5e-78 pir:T31463; probable diapophytoene dehydrogenase crtN -; E=5e-67 COG: VNG1684G; COG1233 Phytoene dehydrogenase and related proteins; E=7e-60 PFAM: PF01266; D-amino acid oxidase; E=0.0003 PF01494; FAD binding domain; E=9.7e-07 PF01946; Thi4 family; E=0.0015.
       0.526
bioB
Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.
       0.523
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
   
 0.503
RB12645
Hypothetical protein.
   
 0.489
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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