Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ndhFNADH subunit 5; PMID: 3035337 best DB hits: BLAST: gb:AAG09461.1; AF217811_11 (AF217811) NADH subunit 5 [Tupaia; E=3e-29 swissprot:P50368; NU5M_SCHCO NADH-UBIQUINONE OXIDOREDUCTASE CHAIN; E=4e-29 embl:CAA50887.1; (X72004) NADH-ubiquinone oxidoreductase subunit; E=1e-28 COG: slr0844; COG1009 NADH:ubiquinone oxidoreductase subunit 5 (chain L); E=3e-29 PAB1402; COG0651 Formate hydrogenlyase subunit 3; E=4e-17 sll1732; COG1009 NADH:ubiquinone oxidoreductase subunit 5 (chain L); E=1e-16 PFAM: PF00662; NADH-Ubiquinone oxidoreductase; E=0.41 PF00361; NADH-Ubiquinone/plastoquinone (; E=1.2e-36. (469 aa)    
Predicted Functional Partners:
nuoM
PMID: 7690854 best DB hits: BLAST: pir:H81796; NADH dehydrogenase (ubiquinone) (EC 1.6.5.3) chain M; E=1e-15 pir:E81220; NADH dehydrogenase I, M chain NMB0258 [imported] -; E=4e-15 swissprot:Q9ZCG0; NUOM_RICPR NADH DEHYDROGENASE I CHAIN M; E=3e-14 COG: NMB0258; COG1008 NADH:ubiquinone oxidoreductase subunit 4 (chain M); E=4e-16 PH1431; COG0651 Formate hydrogenlyase subunit 3; E=6e-13 HP1272; COG1008 NADH:ubiquinone oxidoreductase subunit 4 (chain M); E=3e-12 PFAM: PF00361; NADH-Ubiquinone/plastoquinone (co; E=2e-07.
 
 0.999
RB10314
Conserved hypothetical protein; PMID: 9537320 best DB hits: BLAST: pir:G70374; hypothetical protein aq_863 - Aquifex aeolicus -----; E=6e-49 pir:H82182; conserved hypothetical protein VC1582 [imported] - Vibrio; E=8e-46 pir:E69745; hypothetical protein ybcD - Bacillus subtilis -----; E=1e-39 COG: aq_863; COG3002 Uncharacterized BCR; E=6e-50 PFAM: PF02873; UDP-N-acetylenolpyruvoylglucosamine; E=0.038; Belongs to the UPF0753 family.
 
 
 0.977
ndh
NADH dehydrogenase; PMID: 6265208 best DB hits: BLAST: pir:S74826; NADH dehydrogenase (EC 1.6.99.3) - Synechocystis sp; E=1e-110 embl:CAA71031.1; (Y09899) putative NADH dehydrogenase [Calothrix; E=1e-106 gb:AAC46302.1; (AF038423) NADH dehydrogenase [Mycobacterium; E=9e-91 COG: slr0851; COG1252 NADH dehydrogenase, FAD-containing subunit; E=1e-111 PFAM: PF01494; FAD binding domain; E=0.015 PF00732; GMC oxidoreductases; E=0.067 PF00070; Pyridine nucleotide-disulphide; E=7.9e-33.
   
 
 0.928
RB1432
Conserved hypothetical protein-putative multisubunit Na+/H+ antiporter; PMID: 11016950 best DB hits: BLAST: gb:AAG19081.1; (AE005007) Vng0565c [Halobacterium sp. NRC-1]; E=5e-11 pir:H71683; hypothetical protein RP285 - Rickettsia prowazekii; E=9e-09 pir:E75113; long hypothetical protein PAB0488 - Pyrococcus abyssi; E=5e-07 COG: VNG0565C; COG1006 Multisubunit Na+/H+ antiporter; E=4e-12 PFAM: PF01898; Protein of unknown function DUF67; E=1.9e-11.
  
 
 0.904
RB6350
PMID: 10984043 best DB hits: BLAST: pir:E83450; probable cytochrome oxidase subunit (cbb3-type) PA1557; E=1e-134 pir:E81050; cytochrome-c oxidase (EC 1.9.3.1) fixN chain NMB1725; E=1e-132 pir:C83452; probable cytochrome oxidase subunit (cbb3-type) PA1554; E=1e-129 COG: PA1557; COG3278 Cbb3-type cytochrome oxidase, subunit 1; E=1e-135 NMB1724; COG2993 Cbb3-type cytochrome oxidase, cytochrome c subunit; E=8e-38 slr1137; COG0843 Heme/copper-type cytochrome/quinol oxidases,; E=6e-12 PFAM: PF00115; Cytochrome C and Quinol oxidase poly; E=3.4e-65 PF02433; Cytochrome C oxidase, mono-heme subu [...]
   
   0.903
RB1436
Conserved hypothetical protein; PMID: 9679194 PMID: 11016950 best DB hits: BLAST: swissprot:O58672; Y944_PYRHO HYPOTHETICAL PROTEIN PH0944 -----; E=0.052 pir:C75465; conserved hypothetical protein - Deinococcus radiodurans; E=0.13 pir:F75101; hypothetical protein PAB0803 - Pyrococcus abyssi; E=0.67 COG: PH0944; COG1320 Multisubunit Na+/H+ antiporter; E=0.005.
 
 
 0.881
RB1431
PMID: 11016950 best DB hits: BLAST: pir:F75113; NADH dehydrogenase I N chain PAB2416 - Pyrococcus abyssi; E=7e-44 gb:AAG19080.1; (AE005007) NADH dehydrogenaseoxidoreductase; E=4e-42 ddbj:BAB05035.1; (AP001511) Na+H+ antiporter [Bacillus; E=1e-41 COG: PAB2416; COG0651 Formate hydrogenlyase subunit 3; E=6e-45 Rv3158; COG1007 NADH:ubiquinone oxidoreductase subunit 2 (chain N); E=6e-30 RP284; COG0651 Formate hydrogenlyase subunit 3; E=4e-29 PFAM: PF00361; NADH-Ubiquinone/plastoquinone (; E=3.2e-58.
 
0.874
RB1430
PMID: 1470679 best DB hits: BLAST: embl:CAC14148.1; (AJ245399) putative NADH-ubiquinone; E=4e-80 gb:AAG19079.1; (AE005006) Vng0562c [Halobacterium sp. NRC-1]; E=4e-57 pir:F71683; NADH dehydrogenase (ubiquinone) (EC 1.6.5.3) I chain L2; E=7e-31 COG: VNG0562C; COG0651 Formate hydrogenlyase subunit 3; E=3e-58 RP283; COG1009 NADH:ubiquinone oxidoreductase subunit 5 (chain L); E=7e-32 BH1316; COG0651 Formate hydrogenlyase subunit 3; E=2e-22 PFAM: PF00662; NADH-Ubiquinone oxidoreductase; E=0.69 PF00361; NADH-Ubiquinone/plastoquinone (; E=2.6e-49.
 
 
0.871
RB1442
Conserved hypothetical protein-putative Na+/H+ antiporter; PMID: 10360571 best DB hits: BLAST: pir:C72280; conserved hypothetical protein - Thermotoga maritima; E=8e-09 pir:A71726; hypothetical protein RP156 - Rickettsia prowazekii; E=3e-08 pir:A75113; hypothetical protein PAB0485 - Pyrococcus abyssi (strain; E=8e-08 COG: TM1205; COG1863 Multisubunit Na+/H+ antiporter; E=8e-10 PFAM: PF01899; Protein of unknown function DUF68; E=1.9e-09.
  
 
 0.862
RB1427
PMID: 1470679 best DB hits: BLAST: embl:CAC14149.1; (AJ245399) putative NADH-ubiquinone; E=9e-90 gb:AAG19078.1; (AE005006) Vng0560c [Halobacterium sp. NRC-1]; E=2e-47 ddbj:BAB05035.1; (AP001511) Na+H+ antiporter [Bacillus; E=3e-26 COG: VNG0560C; COG0651 Formate hydrogenlyase subunit 3; E=2e-48 BH1319_1; COG1009 NADH:ubiquinone oxidoreductase subunit 5 (chain L); E=1e-21 PH1452; COG0651 Formate hydrogenlyase subunit 3; E=6e-21 PFAM: PF00361; NADH-Ubiquinone/plastoquinone (co; E=1.4e-36.
 
 
0.861
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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