Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RB10326Best DB hits: BLAST: pir:D83631; probable sulfate transporter PA0103 [imported] -; E=6e-41 pir:B70979; hypothetical protein Rv3273 - Mycobacterium tuberculosis; E=2e-37 pir:T36683; probable integral membrane protein - Streptomyces; E=7e-31 COG: PA0103; COG0659 Sulfate permease and related transporters (MFS; E=6e-42 PFAM: PF00916; Sulfate transporter family; E=5.9e-11. (588 aa)    
Predicted Functional Partners:
RB11975
Polyketide synthase; PMID: 10662695 PMID: 10649995 best DB hits: BLAST: gb:AAF26921.1; AF210843_18 (AF210843) polyketide synthase [Sorangium; E=0.0 gb:AAF26923.1; AF210843_20 (AF210843) polyketide synthase [Sorangium; E=0.0 gb:AAF62883.1; AF217189_6 (AF217189) epoD [Sorangium cellulosum]; E=0.0 COG: BS_fabD; COG0331 (acyl-carrier-protein) S-malonyltransferase; E=7e-31 PA2965; COG0304 3-oxoacyl-(acyl-carrier-protein) synthase I; E=3e-28 PA5234; COG0604 NADPH:quinone reductase and related Zn-dependent; E=2e-27 PFAM: PF00108; Thiolase, N-terminal domain; E=7.3e-07 PF00109; Beta-ketoacyl s [...]
 
 
 
 0.793
RB10322
Two-component sensor histidine kinase; PMID: 10086841 PMID: 10086842 PMID: 10192928 best DB hits: BLAST: ddbj:BAB05639.1; (AP001513) two-component sensor histidine kinase; E=5e-22 swissprot:Q06067; ATOS_ECOLI SENSOR PROTEIN ATOS ----- pir:; E=1e-21 pir:S70528; sensor protein pilS - Myxococcus xanthus -----gb:; E=2e-21 COG: BH1920; COG0642 Sensory transduction histidine kinases; E=5e-23 PFAM: PF00785; PAC motif; E=0.099 PF00512; His Kinase A (phosphoacceptor) doma; E=7.9e-10 PF02518; Histidine kinase-, DNA gyrase B-, p; E=1.1e-33.
     
 0.773
atoC
Acetoacetate metabolism regulatory protein atoC; PMID: 9278503 PMID: 9097040 PMID: 8346225 best DB hits: BLAST: swissprot:Q06065; ATOC_ECOLI ACETOACETATE METABOLISM REGULATORY; E=6e-93 pir:F71315; probable response regulatory protein (atoC) - syphilis; E=7e-93 gb:AAF33506.1; (AF170176) Salmonella typhimurium transcriptional; E=3e-89 COG: atoC; COG2204 AAA superfamily ATPases with N-terminal receiver; E=5e-94 PFAM: PF00072; Response regulator receiver doma; E=1.5e-34 PF00158; Sigma-54 interaction domain; E=1.2e-133.
       0.773
RB10324
Hypothetical protein.
       0.773
RB10314
Conserved hypothetical protein; PMID: 9537320 best DB hits: BLAST: pir:G70374; hypothetical protein aq_863 - Aquifex aeolicus -----; E=6e-49 pir:H82182; conserved hypothetical protein VC1582 [imported] - Vibrio; E=8e-46 pir:E69745; hypothetical protein ybcD - Bacillus subtilis -----; E=1e-39 COG: aq_863; COG3002 Uncharacterized BCR; E=6e-50 PFAM: PF02873; UDP-N-acetylenolpyruvoylglucosamine; E=0.038; Belongs to the UPF0753 family.
     0.711
sui1
Best DB hits: BLAST: swissprot:O26118; SUI1_METTH PROTEIN TRANSLATION FACTOR SUI1; E=2e-09 swissprot:Q57902; SUI1_METJA PROTEIN TRANSLATION FACTOR SUI1; E=5e-09 pir:H72542; hypothetical protein APE1629 - Aeropyrum pernix (strain; E=7e-09 COG: MTH10; COG0023 Translation initiation factor (SUI1); E=2e-10 PFAM: PF01253; Translation initiation factor SUI1; E=1.8e-12.
       0.682
ppk
Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP); Belongs to the polyphosphate kinase 1 (PPK1) family.
      
 0.630
perA
Peroxidase/catalase; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily.
      
 0.618
agrA
Probable Beta-agarase [Precursor]; PMID: 11722934 best DB hits: BLAST: swissprot:P13734; AGAR_ALTAT BETA-AGARASE PRECURSOR -----pir:; E=1e-10.
      
 0.618
fucA
alpha-L-fucosidase; PMID: 2803312 PMID: 2894306 best DB hits: BLAST: pir:B82515; alpha-L-fucosidase XF2714 [imported] - Xylella; E=4e-71 embl:CAC24067.1; (AL512981) Hypothetical [Sulfolobus; E=3e-67 pir:S10235; alpha-L-fucosidase (EC 3.2.1.51) precursor - rat; E=8e-51 PFAM: PF01120; Alpha-L-fucosidase; E=4.4e-27.
      
 0.618
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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