STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
glgCGlucose-1-phosphate adenylyltransferase; PMID: 1325205 best DB hits: BLAST: swissprot:P30521; GLGC_ANASP GLUCOSE-1-PHOSPHATE; E=1e-102 prf:1905422A; ADP-glucose pyrophosphorylase [Synechocystis sp.]; E=1e-101 swissprot:P52415; GLGC_SYNY3 GLUCOSE-1-PHOSPHATE; E=1e-101 COG: slr1176; COG0448 ADP-glucose pyrophosphorylase; E=1e-102 MTH1759; COG1208 Nucleoside-diphosphate-sugar pyrophosphorylases; E=3e-27 BH1086; COG0448 ADP-glucose pyrophosphorylase; E=3e-13 PFAM: PF00483; Nucleotidyl transferase; E=8.7e-62 PF00132; Bacterial transferase hexapep; E=0.029; Belongs to the bacterial/plant glu [...] (429 aa)    
Predicted Functional Partners:
glgA
Glycogen synthase; Synthesizes alpha-1,4-glucan chains using ADP-glucose.
 
 0.996
glgP
Phosphorylase 2; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.
 
 
 0.982
malQ
4-alpha-glucanotransferase; PMID: 10677288 best DB hits: BLAST: swissprot:O87172; MALQ_THEAQ 4-ALPHA-GLUCANOTRANSFERASE; E=1e-119 swissprot:P72785; MALQ_SYNY3 4-ALPHA-GLUCANOTRANSFERASE; E=1e-118 swissprot:P29851; MALQ_STRPN 4-ALPHA-GLUCANOTRANSFERASE; E=1e-114 COG: sll1676; COG1640 4-alpha-glucanotransferase; E=1e-119 PFAM: PF02446; 4-alpha-glucanotransferase; E=3.9e-185.
 
  
 0.931
RB2160
Alpha-amylase; PMID: 2453362 best DB hits: BLAST: swissprot:P09961; AMY1_DICTH ALPHA-AMYLASE 1 (1,4-ALPHA-D-GLUCAN; E=1e-120 ddbj:BAA22063.1; (D88253) 4-alpha-glucanotransferase; E=1e-114 ddbj:BAA22062.1; (D87907) 4-alpha-glucanotransferase [Pyrococcus; E=1e-112 COG: PAB0118; COG1449 Alpha-amylase/alpha-mannosidase; E=1e-111 Rv3031; COG1543 Uncharacterized ACR; E=1e-04.
 
  
 0.921
pmm
Phosphomannomutase; PMID: 8083177 best DB hits: BLAST: gb:AAD56627.1; AF165218_2 (AF165218) Pgm [Streptococcus; E=2e-83 ddbj:BAB04825.1; (AP001510) phosphomannomutase [Bacillus; E=5e-79 swissprot:P18159; YHXB_BACSU PROBABLE PHOSPHOMANNOMUTASE (PMM); E=1e-77 COG: BH1106; COG1109 Phosphomannomutase; E=5e-80 VC2095; COG0033 Phosphoglucomutase; E=3e-11 PH0923; COG1109 Phosphomannomutase; E=5e-11 PFAM: PF02878; Phosphoglucomutase/phosphomannomu; E=1.6e-13 PF02880; Phosphoglucomutase/phosphomannomu; E=0.023 PF00408; Phosphoglucomutase/phosphomannomu; E=0.76.
  
 
 0.919
glgC-2
ADP-glucose pyrophosphorylase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
  
  
 
0.918
hasC
PMID: 7499387 best DB hits: BLAST: pir:A75096; UTP--glucose-1-phosphate uridylyltransferase (EC; E=3e-20 gb:AAD32398.1; AAD32398 (AF065404) pXO1-94 [Bacillus anthracis]; E=4e-19 swissprot:Q54713; HASC_STRPY UTP--GLUCOSE-1-PHOSPHATE; E=2e-17 COG: PAB0771; COG1210 UDP-glucose pyrophosphorylase; E=3e-21 PAB0784; COG1209 dTDP-glucose pyrophosphorylase; E=3e-04 PFAM: PF00483; Nucleotidyl transferase; E=0.014.
     
 0.912
glgB
1,4-alpha-glucan branching enzyme (glycogen branching enzyme); Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
  
 0.841
sps
Sucrose-phosphate synthase 1; PMID: 1840396 PMID: 10411273 best DB hits: BLAST: pir:S75935; hypothetical protein - Synechocystis sp. (strain PCC; E=1e-155 pir:T04062; sucrose-phosphate synthase homolog F28M11.40 - Arabidopsis; E=6e-91 pir:T04103; sucrose-phosphate synthase (EC 2.4.1.14) 1 - rice; E=1e-87 COG: sll0045_1; COG0438 Predicted glycosyltransferases; E=1e-111 sll0045_2; COG0561 Predicted hydrolases of the HAD superfamily; E=8e-40 PH1844; COG0438 Predicted glycosyltransferases; E=2e-11 PFAM: PF00534; Glycosyl transferases group 1; E=2.6e-18 PF00702; haloacid dehalogenase-like h [...]
    
 0.841
RB12082
Similar to hydrolase-putative phosphatase or haloacid dehydrogenase; PMID: 11466286 best DB hits: BLAST: pir:A75406; hydrolase - Deinococcus radiodurans (strain R1) -----; E=0.048 gb:AAG59075.1; AE005619_8 (AE005619) putative phosphatase; E=0.11 pir:S40829; hypothetical 23.5K protein (glnA-fdhE intergenic region); E=0.12 COG: DR1344; COG1011 Predicted hydrolases of the HAD superfamily; E=0.005 PFAM: PF00702; haloacid dehalogenase-like hydrolas; E=0.72.
   
 
  0.802
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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