STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
spoVGProbable stage V sporulation protein G-putative protein involved in regulation of septum location; PMID: http://us.expasy.org/cgi-bin/niceprot.pl?P28016 best DB hits: BLAST: ddbj:BAB03783.1; (AP001507) stage V sporulation protein G; E=3e-11 swissprot:P28016; SP5G_BACME STAGE V SPORULATION PROTEIN G -----; E=8e-10 swissprot:P28015; SP5G_BACSU STAGE V SPORULATION PROTEIN G -----; E=1e-09 COG: BH0064; COG2088 Uncharacterized protein, involved in the regulation; E=3e-12 BS_spoVG; COG2088 Uncharacterized protein, involved in the; E=1e-10 AF1778; COG2088 Uncharacterized protein, involved in [...] (235 aa)    
Predicted Functional Partners:
ispE
Probable 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
       0.806
sun
Sun/nucleolar protein family protein-putative tRNA and rRNA cytosine-C5-methylase; Best DB hits: BLAST: pir:A82193; Sunnucleolar protein family protein VC1502 [imported] -; E=3e-23 gb:AAG56825.1; AE005406_4 (AE005406) putative nucleolar proteins; E=2e-21 pir:C64945; probable rRNA methylase yebU - Escherichia coli -----; E=5e-21 COG: yebU_1; COG0144 tRNA and rRNA cytosine-C5-methylases; E=5e-22 PFAM: PF01189; NOL1/NOP2/sun family; E=1.1e-24; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
       0.773
RB10535
Hypothetical protein-putative transmembrane protein.
       0.773
RB10538
Best DB hits: BLAST: pir:E70410; hypothetical protein aq_1276 - Aquifex aeolicus -----; E=2e-15 gb:AAA96792.1; (U51683) ORF9; hypothetical protein [Brucella; E=4e-14 pir:G71632; hypothetical protein RP730 - Rickettsia prowazekii; E=8e-12.
       0.773
rpoB
DNA-directed RNA polymerase beta chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
      
 0.715
lpdX
UDP-3-O-(R-3-hydroxymyristoyl)-glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
       0.671
yacI
Creatine kinase-putative ATP:guanido kinase (YacI); Catalyzes the specific phosphorylation of arginine residues in proteins; Belongs to the ATP:guanido phosphotransferase family.
  
     0.647
yacH
Conserved hypothetical protein; Best DB hits: BLAST: ddbj:BAA90847.1; (AB031211) YacH [Bacillus halodurans] -----; E=2e-08 swissprot:P37569; YACH_BACSU HYPOTHETICAL 21.0 KD PROTEIN IN; E=5e-08 gb:AAC44444.1; (U40604) ORF2; putative 19 kDa protein [Listeria; E=2e-05 PFAM: PF02151; UvrB/uvrC motif; E=4.7e-08.
  
     0.646
glyS
glycyl-tRNA synthetase; Catalyzes the attachment of glycine to tRNA(Gly). Belongs to the class-II aminoacyl-tRNA synthetase family.
 
   
 0.518
rpoA-2
PMID: 9835038 best DB hits: BLAST: swissprot:O50634; RPOA_BACHD DNA-DIRECTED RNA POLYMERASE ALPHA; E=2e-09 swissprot:Q9Z3E7; RPOA_XANCP DNA-DIRECTED RNA POLYMERASE ALPHA; E=4e-09 gb:AAD00325.2; (U79735) RNA polymerase ALPHA subunit [Xanthomonas; E=4e-09 COG: BH0162; COG0202 DNA-directed RNA polymerase alpha subunit/40 kD; E=2e-10 PFAM: PF00515; TPR Domain; E=0.87 PF01000; Bacterial RNA polymerase, alpha; E=6.5e-12.
  
     0.511
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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