STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RB10587Conserved hypothetical protein-putative phosphoesterase; Best DB hits: BLAST: pir:F75129; hypothetical protein PAB0562 - Pyrococcus abyssi (strain; E=4e-07 embl:CAC23276.1; (AL512965) hypothetical [Sulfolobus; E=1e-05 pir:A69108; probable phosphoesterase (EC 3.1.-.-) MTH1803 -; E=2e-04 COG: PAB0562; COG1407 Predicted ICC-like phosphoesterases; E=3e-08. (225 aa)    
Predicted Functional Partners:
dnlI
Thermostable DNA ligase; PMID: 8843436 best DB hits: BLAST: embl:CAC01484.1; (AL391017) putative DNA ligase [Streptomyces; E=5e-32 swissprot:P56709; DNLI_PYRFU THERMOSTABLE DNA LIGASE; E=4e-30 embl:CAC21199.1; (AJ133713) DNA ligase [Thermococcus fumicolans]; E=4e-29 COG: VNG0881G; COG1793 ATP-dependent DNA ligase; E=5e-29 PFAM: PF01068; DNA ligase; E=1.2e-28.
 
   
 0.821
helX
Putative ATP-dependent helicase; PMID: 8688087 best DB hits: BLAST: pir:D75091; large helicase-related protein (lhr-2) PAB0744 -; E=1e-73 ref:NP_071281.1; large helicase-related protein (lhr-2); E=4e-71 swissprot:Q57742; HELX_METJA PUTATIVE ATP-DEPENDENT HELICASE; E=1e-70 COG: PAB0744; COG1201 Lhr-like helicases; E=1e-74 BS_yprA; COG1205 Distinct helicase family with a unique C-terminal; E=5e-18 PFAM: PF00270; DEAD/DEAH box helicase; E=2.1e-16 PF00271; Helicase conserved C-terminal doma; E=5.5e-14.
 
    0.816
RB1977
Conserved hypothetical protein-putative cleavage and polyadenylation specifity factor protein; PMID: 9679194 best DB hits: BLAST: gb:AAF55578.1; (AE003723) CG7698 gene product [Drosophila; E=3e-09 pir:E71119; hypothetical protein PH0724 - Pyrococcus horikoshii; E=1e-05 gb:AAF19420.1; AF203969_1 (AF203969) cleavage and polyadenylation; E=3e-05 COG: PH0724; COG1236 Predicted exonuclease of the beta-lactamase fold; E=1e-06 PH1404; COG1782 Predicted metal-dependent RNase, consists of a; E=0.001 VC0264; COG1236 Predicted exonuclease of the beta-lactamase fold; E=0.002 PFAM: PF00753; Metallo [...]
 
     0.807
pepQ
Best DB hits: BLAST: gb:AAG19595.1; (AE005049) X-pro aminopeptidase homolog; PepQ2; E=1e-43 gb:AAB89220.1; (AE000962) X-pro aminopeptidase (pepQ); E=3e-16 swissprot:Q10698; YK89_MYCTU PROBABLE DIPEPTIDASE RV2089C -----; E=4e-16 COG: VNG1233G; COG0006 Xaa-Pro aminopeptidase; E=1e-44 PFAM: PF00557; metallopeptidase family M24; E=0.3; Belongs to the peptidase M24B family.
       0.773
RB10589
Hypothetical protein.
       0.718
RB10590
PMID: 10368134 best DB hits: BLAST: swissprot:P75920; MDOC_ECOLI GLUCANS BIOSYNTHESIS PROTEIN MDOC; E=2e-10 gb:AAG55793.1; AE005315_7 (AE005315) orf, hypothetical protein; E=2e-09 embl:CAB77037.1; (AJ245997) hypothetical protein [Xanthomonas; E=0.003 PFAM: PF00023; Ank repeat; E=1e-05.
       0.718
RB10583
Conserved hypothetical protein-putative containing TPR-repeat; Best DB hits: BLAST: pir:B70374; conserved hypothetical protein aq_854 - Aquifex aeolicus; E=1e-05 ddbj:BAA91540.1; (AK001182) unnamed protein product [Homo; E=0.12 embl:CAB98267.1; (AJ276171) ASPIC [Homo sapiens]; E=0.12 COG: aq_854; COG0457 TPR-repeat-containing proteins; E=1e-06 PFAM: PF00515; TPR Domain; E=0.059.
       0.513
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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