STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RB10614PMID: 11157937 PMID: 11481430 best DB hits: BLAST: swissprot:Q9R9N0; LPSD_RHIME LIPOPOLYSACCHARIDE CORE BIOSYNTHESIS; E=4e-17 swissprot:Q9R9N1; LPSE_RHIME LIPOPOLYSACCHARIDE CORE BIOSYNTHESIS; E=2e-16 ddbj:BAB07431.1; (AP001519) BH3712~unknown conserved protein; E=3e-14 COG: DR0713; COG0438 Predicted glycosyltransferases; E=3e-17 PFAM: PF00534; Glycosyl transferases group 1; E=1e-30. (369 aa)    
Predicted Functional Partners:
RB2474
Probable hexosyltransferase; PMID: 10360571 best DB hits: BLAST: pir:E72354; probable hexosyltransferase (EC 2.4.1.-) TM0622 -; E=3e-22 pir:C70036; capsular polysaccharide biosynthesis homolog yveN -; E=7e-12 pir:A82676; conserved hypothetical protein XF1470 [imported] -; E=2e-10 COG: TM0622; COG0438 Predicted glycosyltransferases; E=3e-23 PFAM: PF00534; Glycosyl transferases group 1; E=6.1e-38.
  
     0.774
RB2485
Probable hexosyltransferase; PMID: 10360571 best DB hits: BLAST: pir:E72354; probable hexosyltransferase (EC 2.4.1.-) TM0622 -; E=5e-20 swissprot:Q9R9N1; LPSE_RHIME LIPOPOLYSACCHARIDE CORE BIOSYNTHESIS; E=4e-10 swissprot:Q9R9N0; LPSD_RHIME LIPOPOLYSACCHARIDE CORE BIOSYNTHESIS; E=1e-09 COG: TM0622; COG0438 Predicted glycosyltransferases; E=4e-21 PFAM: PF00534; Glycosyl transferases group 1; E=1.1e-22.
  
     0.759
RB10616
Altronate hydrolase; PMID: 9278503 PMID: 3038546 best DB hits: BLAST: ddbj:BAB04209.1; (AP001508) altronate hydrolase [Bacillus; E=6e-65 gb:AAG58224.1; AE005539_1 (AE005539) altronate hydrolase; E=2e-64 swissprot:P42604; UXAA_ECOLI ALTRONATE HYDROLASE (ALTRONIC ACID; E=2e-63 COG: BH0490; COG2721 Altronate dehydratase; E=6e-66.
       0.671
RB3751
UDP-glucose 4-epimerase homolog; PMID: 9174344 best DB hits: BLAST: gb:AAB84886.1; (AE000823) UDP-glucose 4-epimerase homolog; E=4e-65 pir:C69149; conserved hypothetical protein MTH380 - Methanobacterium; E=4e-65 gb:AAG18703.1; (AE004975) GDP-D-mannose dehydratase; Gmd; E=9e-61 COG: MTH380; COG0451 Nucleoside-diphosphate-sugar epimerases; E=4e-66 aq_1069; COG1087 UDP-glucose 4-epimerase; E=1e-26 PFAM: PF00106; short chain dehydrogenase; E=0.0021 PF01073; 3-beta hydroxysteroid dehydrogenase; E=1.3e-07 PF01370; NAD dependent epimerase/dehydratase; E=3.7e-88.
  
    0.586
amsG
UDP-galactose-lipid carrier transferase; PMID: 7596293 best DB hits: BLAST: swissprot:Q57491; Y872_HAEIN HYPOTHETICAL SUGAR TRANSFERASE HI0872; E=3e-56 swissprot:Q46628; AMSG_ERWAM UDP-GALACTOSE-LIPID CARRIER; E=5e-56 pir:S61891; undecaprenyl-phosphate galactosephosphotransferase (EC; E=5e-56 COG: HI0872; COG2148 Sugar transferases involved in lipopolysaccharide; E=2e-57 PFAM: PF00895; ATP synthase protein 8; E=0.37 PF02397; Bacterial sugar transferase; E=3.6e-89.
 
  
 0.540
RB9168
Nucleotide sugar epimerase; PMID: 10531250 best DB hits: BLAST: pir:G70415; nucleotide sugar epimerase - Aquifex aeolicus -----; E=5e-90 ddbj:BAB07428.1; (AP001519) nucleotide sugar epimerase; E=6e-57 gb:AAD50494.1; AF172324_12 (AF172324) WbnF [Escherichia coli]; E=2e-55 COG: aq_1335; COG0451 Nucleoside-diphosphate-sugar epimerases; E=5e-91 XF0255; COG1088 dTDP-D-glucose 4,6-dehydratase; E=1e-23 PA1384; COG1087 UDP-glucose 4-epimerase; E=1e-23 PFAM: PF00106; short chain dehydrogenase; E=0.16 PF01370; NAD dependent epimerase/dehydratase; E=8.9e-98.
  
    0.510
sucC
succinyl-CoA synthetase (beta subunit); Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
    0.503
RB10436
Mannosyl transferase; PMID: 10978535 best DB hits: BLAST: pir:S22620; hypothetical protein 18.9 - Salmonella choleraesuis; E=7e-55 ddbj:BAB03210.1; (AB046360) putative glycosyltransferase; E=4e-53 ddbj:BAA94399.1; (AB041266) mannosyl transferase [Actinobacillus; E=2e-52 COG: DRA0040; COG0438 Predicted glycosyltransferases; E=1e-50 PFAM: PF00534; Glycosyl transferases group 1; E=2.4e-29.
  
     0.500
RB2471
Conserved hypothetical protein-putative poly(glycerol-phosphate) alpha-glucosyltransferase; PMID: 8905231 best DB hits: BLAST: pir:S74778; hypothetical protein slr1077 - Synechocystis sp. (strain; E=5e-34 gb:AAD43836.1; AF076290_6 (AF076290) putative mannosyltransferase; E=4e-16 embl:CAB43611.1; (AJ239004) galactosyl transferase [Streptococcus; E=9e-11 COG: slr1077; COG0438 Predicted glycosyltransferases; E=5e-35 PFAM: PF00534; Glycosyl transferases group 1; E=5e-21.
  
     0.491
RB2500
UDP-glucose 4-epimerase; PMID: 11337471 best DB hits: BLAST: gb:AAK04309.1; AE006259_3 (AE006259) UDP-glucose 4-epimerase; E=1e-23 swissprot:Q57664; GALE_METJA PUTATIVE UDP-GLUCOSE 4-EPIMERASE; E=1e-23 gb:AAG18701.1; (AE004975) UDP-glucose 4-epimerase; GalE2; E=3e-23 COG: MJ0211; COG0451 Nucleoside-diphosphate-sugar epimerases; E=1e-24 MTH631; COG1087 UDP-glucose 4-epimerase; E=5e-20 PH0378; COG0451 Nucleoside-diphosphate-sugar epimerases; E=1e-19 PFAM: PF01073; 3-beta hydroxysteroid dehydrogenase; E=0.64 PF00106; short chain dehydrogenase; E=0.0027 PF01370; NAD dependent epimerase/deh [...]
  
    0.488
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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