STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RB10616Altronate hydrolase; PMID: 9278503 PMID: 3038546 best DB hits: BLAST: ddbj:BAB04209.1; (AP001508) altronate hydrolase [Bacillus; E=6e-65 gb:AAG58224.1; AE005539_1 (AE005539) altronate hydrolase; E=2e-64 swissprot:P42604; UXAA_ECOLI ALTRONATE HYDROLASE (ALTRONIC ACID; E=2e-63 COG: BH0490; COG2721 Altronate dehydratase; E=6e-66. (634 aa)    
Predicted Functional Partners:
uxuB
D-mannonate oxidoreductase; PMID: 7610040 best DB hits: BLAST: pir:D83353; mannitol dehydrogenase PA2342 [imported] - Pseudomonas; E=1e-116 gb:AAC04472.1; (AF007800) mannitol dehydrogenase [Pseudomonas; E=1e-111 embl:CAA96356.1; (Z71688) ORF YNR073c [Saccharomyces cerevisiae]; E=1e-102 COG: PA2342; COG0246 Mannitol-1-phosphate/altronate dehydrogenases; E=1e-117 PFAM: PF01232; Mannitol dehydrogenase; E=9.3e-176.
  
 0.885
kdgK
2-keto-3-deoxygluconate kinase; PMID: 8157608 best DB hits: BLAST: pir:G72422; 2-keto-3-deoxygluconate kinase - Thermotoga maritima; E=1e-15 embl:CAB61818.1; (AL133236) putative sugar kinase [Streptomyces; E=2e-08 pir:D83362; probable 2-ketogluconate kinase PA2261 [imported] -; E=2e-06 COG: TM0067; COG0524 Sugar kinases, ribokinase family; E=1e-16 PFAM: PF00294; pfkB family carbohydrate kinase; E=3.8e-10.
 
  
 0.860
rpiB
PMID: 8576032 best DB hits: BLAST: ddbj:BAB07486.1; (AP001519) ribose 5-phosphate epimerase (pentose; E=3e-30 pir:H70397; ribose 5-phosphate isomerase B - Aquifex aeolicus; E=9e-29 embl:CAA07515.1; (AJ007446) hypothetical protein [Thermotoga; E=7e-27 COG: BH3767; COG0698 Ribose 5-phosphate isomerase RpiB; E=2e-31 PFAM: PF02502; Ribose/Galactose Isomerase; E=1.1e-35.
     
 0.803
rpiB-2
PMID: 8576032 best DB hits: BLAST: ddbj:BAB07486.1; (AP001519) ribose 5-phosphate epimerase (pentose; E=2e-28 swissprot:P37351; RPIB_ECOLI RIBOSE 5-PHOSPHATE ISOMERASE B; E=3e-27 pir:H70397; ribose 5-phosphate isomerase B - Aquifex aeolicus; E=3e-27 COG: BH3767; COG0698 Ribose 5-phosphate isomerase RpiB; E=2e-29 PFAM: PF02502; Ribose/Galactose Isomerase; E=5e-43.
     
 0.803
rpe
Ribulose-phosphate 3-epimerase; PMID: 10625676 best DB hits: BLAST: pir:G82052; ribulose-phosphate 3-epimerase VC2625 [imported] -; E=1e-42 gb:AAK03703.1; (AE006199) Dod [Pasteurella multocida]; E=1e-40 gb:AAF01048.1; AF189365_1 (AF189365) D-ribulose-5-phosphate; E=3e-40 COG: VC2625; COG0036 Pentose-5-phosphate-3-epimerase; E=1e-43 PFAM: PF00834; Ribulose-phosphate 3 epimerase; E=1.8e-85.
     
 0.800
6pgD
6-phosphogluconate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
     
 0.800
RB5319
Best DB hits: BLAST: gb:AAB90381.1; (AE001045) D-arabino 3-hexulose 6-phosphate; E=1e-33 pir:B71209; probable D-arabino 3-hexulose 6-phosphate formaldehyde; E=8e-33 pir:C75022; d-arabino 3-hexulose 6-phosphate formaldehyde lyase; E=7e-28 COG: AF0861_1; COG0269 3-hexulose-6-phosphate synthase and related; E=1e-33 sgaH; COG0269 3-hexulose-6-phosphate synthase and related proteins; E=4e-10 VCA0242; COG0269 3-hexulose-6-phosphate synthase and related; E=3e-09 PFAM: PF00834; Ribulose-phosphate 3 epimerase; E=0.56 PF02581; Thiamine monophosphate synthas; E=0.01.
     
  0.800
RB10614
PMID: 11157937 PMID: 11481430 best DB hits: BLAST: swissprot:Q9R9N0; LPSD_RHIME LIPOPOLYSACCHARIDE CORE BIOSYNTHESIS; E=4e-17 swissprot:Q9R9N1; LPSE_RHIME LIPOPOLYSACCHARIDE CORE BIOSYNTHESIS; E=2e-16 ddbj:BAB07431.1; (AP001519) BH3712~unknown conserved protein; E=3e-14 COG: DR0713; COG0438 Predicted glycosyltransferases; E=3e-17 PFAM: PF00534; Glycosyl transferases group 1; E=1e-30.
       0.671
RB6095
Conserved hypothetical protein; PMID: 10484179 best DB hits: BLAST: ddbj:BAB04212.1; (AP001508) BH0493~unknown [Bacillus halodurans]; E=4e-12 gb:AAF77061.1; AF266466_3 (AF266466) putative hexuronic acid; E=0.003 gb:AAK05726.1; AE006393_5 (AE006393) glucuronate isomerase (EC; E=0.57.
 
  
 0.635
sucC
succinyl-CoA synthetase (beta subunit); Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
       0.572
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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