Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RB10673Conserved hypothetical protein-putative transmembrane protein; Best DB hits: BLAST: pir:S22614; hypothetical protein - Salmonella choleraesuis -----; E=9e-25. (458 aa)    
Predicted Functional Partners:
RB10670
Conserved hypothetical protein-putative hydrolase of the alkaline phosphatase superfamily; Best DB hits: BLAST: pir:B83531; hypothetical protein PA0924 [imported] - Pseudomonas; E=1e-12 pir:D82055; conserved hypothetical protein VC2600 [imported] -; E=7e-06 gb:AAK03767.1; (AE006205) unknown [Pasteurella multocida]; E=0.12 COG: PA0924; COG3083 Predicted hydrolase of alkaline phosphatase; E=1e-13.
       0.773
RB10672
Hypothetical protein.
       0.773
RB10674
Hypothetical protein.
       0.773
amsG
UDP-galactose-lipid carrier transferase; PMID: 7596293 best DB hits: BLAST: swissprot:Q57491; Y872_HAEIN HYPOTHETICAL SUGAR TRANSFERASE HI0872; E=3e-56 swissprot:Q46628; AMSG_ERWAM UDP-GALACTOSE-LIPID CARRIER; E=5e-56 pir:S61891; undecaprenyl-phosphate galactosephosphotransferase (EC; E=5e-56 COG: HI0872; COG2148 Sugar transferases involved in lipopolysaccharide; E=2e-57 PFAM: PF00895; ATP synthase protein 8; E=0.37 PF02397; Bacterial sugar transferase; E=3.6e-89.
  
  
 0.761
ugdH
UDP-glucose 6-dehydrogenase; PMID: 8938413 best DB hits: BLAST: pir:T51527; UDP-glucose dehydrogenase-like protein - Arabidopsis; E=1e-155 ddbj:BAB02581.1; (AP001309) UDP-glucose dehydrogenase; E=1e-151 swissprot:Q96558; UGDH_SOYBN UDP-GLUCOSE 6-DEHYDROGENASE (UDP-GLC; E=1e-150 COG: aq_024; COG1004 Predicted UDP-glucose 6-dehydrogenase; E=2e-61 VC0918; COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase; E=1e-27 PA3540; COG1004 Predicted UDP-glucose 6-dehydrogenase; E=8e-26 PFAM: PF00984; UDP-glucose/GDP-mannose dehydro; E=2.6e-180; Belongs to the UDP-glucose/GDP-mannose dehydrogena [...]
  
  
 0.559
rfbB
dTDP-glucose-4,6-dehydratase; PMID: 8022265 best DB hits: BLAST: gb:AAG35060.1; AF314183_2 (AF314183) dTDP-glucose-4,6-dehydratase; E=1e-110 gb:AAF33465.1; (AF233324) 89% identity with E. coli; E=1e-107 swissprot:P55294; RFBB_NEIMB DTDP-GLUCOSE 4,6-DEHYDRATASE -----; E=1e-106 COG: NMB0063; COG1088 dTDP-D-glucose 4,6-dehydratase; E=1e-107 PFAM: PF01073; 3-beta hydroxysteroid dehydro; E=0.53 PF00106; short chain dehydrogenase; E=0.073 PF01370; NAD dependent epimerase/dehyd; E=6e-141; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.
  
  
 0.546
rfbE
CDP-tyvelose epimerase; PMID: 96125720 PMID: 97158136 PMID: 2793833 best DB hits: BLAST: gb:AAB48319.1; (U29691) CDP-tyvelose epimerase [Yersinia; E=2e-29 swissprot:P14169; RFBE_SALTI CDP-TYVELOSE-2-EPIMERASE -----; E=3e-27 pir:B33604; rfbE protein - Salmonella sp; E=7e-26 COG: HI0873; COG1088 dTDP-D-glucose 4,6-dehydratase; E=5e-19 BH3649; COG0451 Nucleoside-diphosphate-sugar epimerases; E=1e-14 PH0414; COG1088 dTDP-D-glucose 4,6-dehydratase; E=1e-14 PFAM: PF01370; NAD dependent epimerase/dehydratase; E=0.0012.
  
  
 0.546
RB10675
Hypothetical protein-putative transmembrane protein.
       0.545
RB10666
Conserved hypothetical protein-putative archaeal protein; Best DB hits: BLAST: pir:F69009; probable membrane protein MTH1074 - Methanobacterium; E=1e-114 embl:CAA48444.1; (X68367) ORF5' [Methanobacterium; E=9e-18 pir:S30585; hypothetical protein 5 - Methanobacterium thermoformicicum; E=6e-17 PFAM: PF01345; Domain of unknown function DUF11; E=0.007.
       0.532
RB10678
Hypothetical protein.
       0.416
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
Server load: low (8%) [HD]