Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
fdhGlutathione-dependent formaldehyde dehydrogenase; PMID: 7926692 best DB hits: BLAST: swissprot:P47734; FADH_METMR GLUTATHIONE-DEPENDENT FORMALDEHYDE; E=1e-160 pir:A75593; alcohol dehydrogenase, zinc-containing - Deinococcus; E=1e-113 pir:B83373; probable alcohol dehydrogenase (Zn-dependent) PA2188; E=7e-84 COG: DRA0005; COG1063 Threonine dehydrogenase and related Zn-dependent; E=1e-114 sll0990; COG1062 Zn-dependent alcohol dehydrogenases, class III; E=7e-20 PFAM: PF00107; Zinc-binding dehydrogenases; E=3e-74. (389 aa)    
Predicted Functional Partners:
RB10730
Hypothetical protein.
       0.773
RB10731
Hypothetical protein.
       0.773
RB10727
Manganese-containing catalase; PMID: 97094642 best DB hits: BLAST: ddbj:BAB05909.1; (AP001514) manganese-containing catalase; E=3e-62 swissprot:P80878; GS80_BACSU GENERAL STRESS PROTEIN 80 (GSP80); E=1e-61 pir:C69854; conserved hypothetical protein yjqC - Bacillus subtilis; E=2e-56.
 
    0.743
RB4404
Hypothetical oxidoreductase yhxD-putative dehydrogenase of the short-chain dehydrogenase family; Best DB hits: BLAST: swissprot:P40398; YHXD_BACSU HYPOTHETICAL OXIDOREDUCTASE IN; E=2e-67 swissprot:P80873; GS39_BACSU GENERAL STRESS PROTEIN 39 (GSP39); E=3e-65 gb:AAG02162.1; AF212041_18 (AF212041) ribitol dehydrogenase; E=8e-65 COG: BS_yhxD; COG1028 Dehydrogenases with different specificities; E=2e-68 BH1511; COG1028 Dehydrogenases with different specificities (related; E=1e-64 DRA0364; COG1028 Dehydrogenases with different specificities; E=1e-62 PFAM: PF00106; short chain dehydrogenase; [...]
  
    0.603
RB10734
Hypothetical protein-signal peptide prediction.
  
    0.532
RB10735
Hypothetical protein-transmembrane prediction.
       0.527
RB6500
Mycocerosate synthase; PMID: 3880746 best DB hits: BLAST: pir:S72705; mycocerosate synthase (EC 2.3.1.111) - Mycobacterium; E=0.0 pir:H70819; probable polyketide synthase - Mycobacterium tuberculosis; E=0.0 gb:AAF62883.1; AF217189_6 (AF217189) epoD [Sorangium cellulosum]; E=1e-180 COG: PA2402_3; COG1020 Non-ribosomal peptide synthetase modules and related; E=4e-99 BS_ppsD_3; COG1020 Non-ribosomal peptide synthetase modules and; E=4e-92 PA2424_2; COG1020 Non-ribosomal peptide synthetase modules and related; E=1e-91 PFAM: PF00108; Thiolase, N-terminal domain; E=2.7e-06 PF00109; Beta-keto [...]
  
  
 0.469
RB10728
Hypothetical protein-signal peptide prediction.
       0.440
RB10729
Hypothetical protein.
       0.440
RB4438
Probable general stress protein 26; PMID: 8012595 best DB hits: BLAST: pir:D75431; probable general stress protein 26 - Deinococcus; E=4e-18 pir:D75427; hypothetical protein - Deinococcus radiodurans (strain; E=2e-07 swissprot:P80238; GS26_BACSU GENERAL STRESS PROTEIN 26 (GSP26); E=0.10.
  
     0.430
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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