STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RB10909Hypothetical protein-transmembrane prediction. (267 aa)    
Predicted Functional Partners:
RB7663
Conserved hypothetical protein-containing P-loop; Best DB hits: BLAST: swissprot:O83845; Y875_TREPA HYPOTHETICAL PROTEIN TP0875 -----; E=1e-09 pir:H72229; conserved hypothetical protein - Thermotoga maritima; E=2e-08 ddbj:BAB04264.1; (AP001508) BH0545~unknown conserved protein; E=1e-05 COG: TP0875; COG0802 Predicted ATPase or kinase; E=1e-10 PFAM: PF02367; Uncharacterised P-loop hydrolase UPF; E=3.9e-22.
  
 
 0.980
tsaD
Glycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.
 
 
 0.944
RB10905
Probable phosphoesterase PH1616; PMID: 9679194 best DB hits: BLAST: pir:H71040; probable phosphoesterase (EC 3.1.-.-) PH1616 -; E=1e-26 swissprot:Q58322; Y912_METJA HYPOTHETICAL PROTEIN MJ0912 -----; E=8e-25 pir:A75174; hypothetical protein PAB1999 - Pyrococcus abyssi (strain; E=2e-24 COG: PH1616; COG0639 Diadenosine tetraphosphatase and related; E=1e-27.
       0.565
RB10907
Probable phosphoesterase PH1616; Best DB hits: BLAST: swissprot:Q58322; Y912_METJA HYPOTHETICAL PROTEIN MJ0912 -----; E=7e-31 pir:H71040; probable phosphoesterase (EC 3.1.-.-) PH1616 -; E=2e-26 pir:A75174; hypothetical protein PAB1999 - Pyrococcus abyssi (strain; E=4e-25 COG: MJ0912; COG0639 Diadenosine tetraphosphatase and related; E=7e-32 PFAM: PF01143; Uncharacterized phosphoesterase fami; E=0.086.
       0.565
birA
Bifunctional protein BirA; PMID: 3899863 PMID: 1409631 best DB hits: BLAST: gb:AAK05878.1; AE006408_2 (AE006408) bifunctional protein BirA (EC; E=1e-17 pir:A83112; BirA bifunctional protein PA4280 [imported] -; E=1e-16 swissprot:P29906; BIRA_PARDE BIOTIN--[ACETYL-COA-CARBOXYLASE]; E=6e-15 COG: PA4280_2; COG0340 Biotin-(acetyl-CoA carboxylase) ligase; E=1e-17 PFAM: PF01317; Biotin protein ligase catalytic doma; E=6.2e-30 PF02237; Biotin protein ligase C terminal dom; E=5.4e-05.
   
    0.537
RB282
Conserved hypothetical protein-putative ATPase; Best DB hits: BLAST: ddbj:BAB03825.1; (AP001507) BH0106~unknown conserved protein; E=2e-52 swissprot:Q06754; YACL_BACSU HYPOTHETICAL 40.9 KD PROTEIN IN; E=4e-51 swissprot:Q48762; YOR6_LISMO HYPOTHETICAL 39.5 KD PROTEIN (ORF6); E=8e-51 COG: BH0106; COG1855 ATPases of the PilT family; E=2e-53 PFAM: PF01850; PIN domain; E=0.11.
 
     0.503
dpoL
Putative DNA polymerase related protein; PMID: 2119891 best DB hits: BLAST: embl:CAB77286.1; (AL160312) putative DNA polymerase related; E=9e-39 gb:AAD56917.1; AF180145_9 (AF180145) hypothetical protein; E=1e-30 embl:CAB56297.1; (AJ249385) hypothetical protein [Pseudomonas; E=3e-30 COG: aq_1693; COG1573 Uracil-DNA glycosylase; E=5e-21.
  
    0.502
RB5620
DNA polymerase, bacteriophage-type; PMID: 1324872 best DB hits: BLAST: pir:E70446; N-terminus of phage SPO1 DNA polymerase - Aquifex; E=2e-28 pir:C71351; probable DNA polymerase, bacteriophage-type - syphilis; E=6e-26 pir:D75359; DNA polymerase-related protein - Deinococcus radiodurans; E=4e-24 COG: aq_1693; COG1573 Uracil-DNA glycosylase; E=2e-29.
  
    0.502
thiL
Thiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family.
  
  
 0.478
guaA-2
GMP synthase; Catalyzes the synthesis of GMP from XMP.
     
 0.474
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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