Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
RB10967Putative oxidoreductase; Best DB hits: BLAST: embl:CAB62729.1; (AL133423) putative oxidoreductase [Streptomyces; E=1e-81 gb:AAG19273.1; (AE005023) quinone oxidoreductase; YfmJ; E=1e-77 pir:A69813; quinone oxidoreductase homolog yfmJ - Bacillus subtilis; E=6e-76 COG: VNG0815G; COG2130 Putative NADP-dependent oxidoreductases; E=1e-78 PA5234; COG0604 NADPH:quinone reductase and related Zn-dependent; E=5e-10 Ta0841; COG1064 Zn-dependent alcohol dehydrogenases; E=2e-05 PFAM: PF00022; Actin; E=0.28 PF00107; Zinc-binding dehydrogenases; E=7.7e-37. (341 aa)    
Predicted Functional Partners:
RB11975
Polyketide synthase; PMID: 10662695 PMID: 10649995 best DB hits: BLAST: gb:AAF26921.1; AF210843_18 (AF210843) polyketide synthase [Sorangium; E=0.0 gb:AAF26923.1; AF210843_20 (AF210843) polyketide synthase [Sorangium; E=0.0 gb:AAF62883.1; AF217189_6 (AF217189) epoD [Sorangium cellulosum]; E=0.0 COG: BS_fabD; COG0331 (acyl-carrier-protein) S-malonyltransferase; E=7e-31 PA2965; COG0304 3-oxoacyl-(acyl-carrier-protein) synthase I; E=3e-28 PA5234; COG0604 NADPH:quinone reductase and related Zn-dependent; E=2e-27 PFAM: PF00108; Thiolase, N-terminal domain; E=7.3e-07 PF00109; Beta-ketoacyl s [...]
  
 
 0.847
RB6500
Mycocerosate synthase; PMID: 3880746 best DB hits: BLAST: pir:S72705; mycocerosate synthase (EC 2.3.1.111) - Mycobacterium; E=0.0 pir:H70819; probable polyketide synthase - Mycobacterium tuberculosis; E=0.0 gb:AAF62883.1; AF217189_6 (AF217189) epoD [Sorangium cellulosum]; E=1e-180 COG: PA2402_3; COG1020 Non-ribosomal peptide synthetase modules and related; E=4e-99 BS_ppsD_3; COG1020 Non-ribosomal peptide synthetase modules and; E=4e-92 PA2424_2; COG1020 Non-ribosomal peptide synthetase modules and related; E=1e-91 PFAM: PF00108; Thiolase, N-terminal domain; E=2.7e-06 PF00109; Beta-keto [...]
  
 
 0.843
gabD
Succinate-semialdehyde dehydrogenase [NADP+]; PMID: 8297211 best DB hits: BLAST: swissprot:O32507; GABD_DEIRA SUCCINATE-SEMIALDEHYDE DEHYDROGENASE; E=1e-118 gb:AAD19405.1; (AF102543) succinic semialdehyde dehydrogenase; E=1e-111 swissprot:Q55585; GABD_SYNY3 PROBABLE SUCCINATE-SEMIALDEHYDE; E=1e-107 COG: DRA0343; COG1012 NAD-dependent aldehyde dehydrogenases; E=1e-119 PFAM: PF00171; Aldehyde dehydrogenase family; E=2.7e-118; Belongs to the aldehyde dehydrogenase family.
  
  
 0.777
pcm
protein-L-isoaspartate O-methyltransferase; Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
   
 
 0.648
mtfB
PMID: 8162191 PMID: 7536735 best DB hits: BLAST: pir:I76776; Mannosyltransferase (EC 5.-.-.-) B - Escherichia coli; E=2e-26 gb:AAF04384.1; AF189151_7 (AF189151) WbdB; mannosyl transferase B; E=2e-26 gb:AAC38771.1; (AF010182) glycosyltransferase WbpY [Pseudomonas; E=3e-21 COG: PA5448; COG0438 Predicted glycosyltransferases; E=3e-22 PFAM: PF00534; Glycosyl transferases group 1; E=2.1e-24.
   
  
 0.622
RB10255
Conserved hypothetical protein-putative mechanosensitive ion channel; PMID: 10952301 best DB hits: BLAST: pir:A82318; conserved hypothetical protein VC0480 [imported] -; E=1e-37 swissprot:O52401; YGGB_EDWIC HYPOTHETICAL 30.6 KDA PROTEIN IN; E=2e-36 pir:B83096; conserved hypothetical protein PA4394 [imported] -; E=2e-31 COG: VC0480; COG0668 Small-conductance mechanosensitive channel; E=1e-38 HI0195.1; COG3264 Small-conductance mechanosensitive channel; E=2e-12 APE1441; COG0668 Small-conductance mechanosensitive channel; E=4e-12 PFAM: PF00924; Uncharacterized protein family UPF00; E=2.7e-52.
      
 0.618
surE
Acid phosphatase SurE; PMID: 8905231 best DB hits: BLAST: swissprot:P73440; YE59_SYNY3 HYPOTHETICAL 24.9 KD PROTEIN SLL1459; E=4e-31 swissprot:O83434; SURE_TREPA STATIONARY-PHASE SURVIVAL PROTEIN; E=3e-22 gb:AAD51394.1; AF117715_3 (AF117715) survival protein homolog; E=4e-20 COG: sll1459; COG0496 Survival protein, predicted acid phosphatase; E=4e-32 PFAM: PF01975; Survival protein SurE; E=9.8e-49.
      
 0.618
exbD
Probable biopolymer transport exbD protein; PMID: 9140974 best DB hits: BLAST: embl:CAB50919.1; (AJ243354) hypothetical protein [Pseudomonas; E=4e-05 pir:F83274; conserved hypothetical protein PA2982 [imported] -; E=7e-05 swissprot:O06434; EXBD_NEIGO BIOPOLYMER TRANSPORT EXBD PROTEIN; E=0.001 COG: PA2982; COG0848 Biopolymer transport protein; E=7e-06 PFAM: PF02472; Biopolymer transport protein ExbD/; E=8.9e-08.
      
 0.618
exbD-2
Probable biopolymer transport ExbD protein; PMID: 2670903 PMID: 10517598 best DB hits: BLAST: gb:AAC78852.1; (AF087669) ExbD [Bordetella bronchiseptica]; E=1e-06 pir:T44783; exbD protein [imported] - Bordetella pertussis -----; E=3e-06 pir:A71687; tolR protein (tolR) RP310 - Rickettsia prowazekii; E=3e-06 COG: RP310; COG0848 Biopolymer transport protein; E=4e-07 PFAM: PF02472; Biopolymer transport protein ExbD/To; E=4.1e-10.
      
 0.618
exbB
Probable biopolymer transport ExbB-related protein; PMID: 8437515 best DB hits: BLAST: pir:D82726; conserved hypothetical protein XF1079 [imported] -; E=8e-21 pir:G83274; probable tolQ-type transport protein PA2983 [imported] -; E=4e-19 embl:CAB50918.1; (AJ243354) hypothetical protein [Pseudomonas; E=8e-16 COG: XF1079; COG0811 Biopolymer transport proteins; E=8e-22 PFAM: PF01618; MotA/TolQ/ExbB proton channel famil; E=3.1e-21.
      
 0.618
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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