Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
sigGProbable RNA-polymerase sigma-E factor; Best DB hits: BLAST: gb:AAD42769.1; AF121849_1 (AF121849) SigG [Synechococcus sp. PCC; E=9e-12 pir:S77368; transcription initiation factor sigma E slr1545 -; E=1e-11 pir:C82583; RNA polymerase sigma-H factor XF2239 [imported] -; E=1e-08 COG: slr1545; COG1595 DNA-directed RNA polymerase specialized sigma; E=1e-12 PFAM: PF00776; Sigma-70 factor (ECF subfamily); E=0.00072 PF00140; Sigma-70 factor; E=0.028. (239 aa)    
Predicted Functional Partners:
rpsH
RNA polymerase sigma-H factor; PMID: 8432708 best DB hits: BLAST: pir:C82583; RNA polymerase sigma-H factor XF2239 [imported] -; E=1e-19 pir:S77368; transcription initiation factor sigma E slr1545 -; E=2e-19 gb:AAD42769.1; AF121849_1 (AF121849) SigG [Synechococcus sp. PCC; E=7e-18 COG: XF2239; COG1595 DNA-directed RNA polymerase specialized sigma; E=1e-20 PFAM: PF00776; Sigma-70 factor (ECF subfamily); E=1.5e-18 PF00140; Sigma-70 factor; E=0.55.
  
     0.771
sigW-4
RNA polymerase sigma factor sigW; PMID: 8432708 PMID: 7961421 best DB hits: BLAST: swissprot:Q45585; SIGW_BACSU RNA POLYMERASE SIGMA FACTOR SIGW; E=1e-15 ddbj:BAB03982.1; (AP001507) RNA polymerase ECF-type sigma factor; E=5e-13 gb:AAF18265.1; U22895_1 (U22895) alternative sigma factor AlgU; E=3e-10 COG: BS_sigW; COG1595 DNA-directed RNA polymerase specialized sigma; E=1e-16 PFAM: PF00776; Sigma-70 factor (ECF subfamily); E=2.9e-11.
  
     0.771
algU
RNA polymerase sigma-H factor; PMID: 8432708 PMID: 7961421 best DB hits: BLAST: gb:AAC45219.1; (U87308) extracytoplasmic function alternative; E=4e-10 gb:AAC45221.1; (U87307) extracytoplasmic function alternative; E=5e-10 pir:H70507; probable sigE protein - Mycobacterium tuberculosis; E=8e-10 COG: Rv1221; COG1595 DNA-directed RNA polymerase specialized sigma; E=7e-11 PFAM: PF00776; Sigma-70 factor (ECF subfamily); E=0.065.
  
     0.770
sigW-2
RNA polymerase sigma factor sigW; PMID: 8432708 best DB hits: BLAST: swissprot:Q45585; SIGW_BACSU RNA POLYMERASE SIGMA FACTOR SIGW; E=3e-23 gb:AAF18265.1; U22895_1 (U22895) alternative sigma factor AlgU; E=6e-18 ddbj:BAB03982.1; (AP001507) RNA polymerase ECF-type sigma factor; E=2e-17 COG: BS_sigW; COG1595 DNA-directed RNA polymerase specialized sigma; E=3e-24 PFAM: PF00776; Sigma-70 factor (ECF subfamily); E=9.9e-15.
  
     0.770
sigW
Probable RNA polymerase sigma factor sigW; PMID: 9274029 best DB hits: BLAST: pir:H70507; probable sigE protein - Mycobacterium tuberculosis; E=6e-14 gb:AAC45221.1; (U87307) extracytoplasmic function alternative; E=2e-13 gb:AAC45219.1; (U87308) extracytoplasmic function alternative; E=5e-13 COG: Rv1221; COG1595 DNA-directed RNA polymerase specialized sigma; E=6e-15 PFAM: PF00776; Sigma-70 factor (ECF subfamily); E=2.1e-09.
  
     0.765
RB12372
RNA polymerase ECF-type sigma factor; PMID: 7889934 best DB hits: BLAST: ddbj:BAB03982.1; (AP001507) RNA polymerase ECF-type sigma factor; E=4e-15 swissprot:Q45585; SIGW_BACSU RNA POLYMERASE SIGMA FACTOR SIGW; E=3e-13 swissprot:Q06198; RPSH_PSEAE RNA POLYMERASE SIGMA-H FACTOR; E=1e-11 COG: BH0263; COG1595 DNA-directed RNA polymerase specialized sigma; E=4e-16 PFAM: PF00776; Sigma-70 factor (ECF subfamily); E=5.4e-10 PF00140; Sigma-70 factor; E=0.53.
  
     0.760
RB6643
Probable RNA polymerase ECF-type sigma factor; PMID: 7961421 best DB hits: BLAST: gb:AAF01335.1; AF190580_1 (AF190580) alternate sigma factor AlgT; E=2e-09 pir:A69872; RNA polymerase ECF-type sigma factor homolog ylaC -; E=2e-09 swissprot:Q06198; RPSH_PSEAE RNA POLYMERASE SIGMA-H FACTOR; E=2e-09 COG: BS_ylaC; COG1595 DNA-directed RNA polymerase specialized sigma; E=2e-10 PFAM: PF00776; Sigma-70 factor (ECF subfamily); E=5.5e-14.
  
     0.707
RB6078
PMID: 9308178 best DB hits: BLAST: swissprot:O05409; SIGZ_BACSU RNA POLYMERASE SIGMA FACTOR SIGZ; E=1e-31 ddbj:BAB03982.1; (AP001507) RNA polymerase ECF-type sigma factor; E=6e-13 pir:C69826; RNA polymerase ECF-type sigma factor homolog yhdM -; E=8e-12 COG: BS_sigZ; COG1595 DNA-directed RNA polymerase specialized sigma; E=1e-32 PFAM: PF00776; Sigma-70 factor (ECF subfamily); E=7.3e-15.
  
     0.673
RB7098
PMID: 9139909 best DB hits: BLAST: gb:AAC45219.1; (U87308) extracytoplasmic function alternative; E=3e-10 pir:H70507; probable sigE protein - Mycobacterium tuberculosis; E=4e-09 ddbj:BAB03982.1; (AP001507) RNA polymerase ECF-type sigma factor; E=2e-08 COG: Rv1221; COG1595 DNA-directed RNA polymerase specialized sigma; E=4e-10 PFAM: PF00776; Sigma-70 factor (ECF subfamily); E=0.028 PF00140; Sigma-70 factor; E=0.00033 PF01381; Helix-turn-helix; E=0.055.
  
     0.666
RB10995
Best DB hits: BLAST: pir:T36717; probable serinethreonine protein kinase - Streptomyces; E=8e-35 ddbj:BAB06223.1; (AP001515) serinethreonine protein kinase; E=4e-34 pir:H69878; probable protein kinase (EC 2.7.1.-) yloP - Bacillus; E=9e-34 COG: BH2504_1; COG0515 Serine/threonine protein kinases; E=3e-35 PFAM: PF00069; Protein kinase domain; E=5.1e-31.
   
   0.592
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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