Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
fesEnterochelin esterase; PMID: 11694506 best DB hits: BLAST: pir:B83340; hypothetical protein PA2451 [imported] - Pseudomonas; E=2e-32 swissprot:O51900; FES_ERWCH ENTEROCHELIN ESTERASE (FERRIC; E=6e-20 gb:AAC46181.1; (U97227) ferric enterochelin esterase homolog; E=2e-18 COG: PA2451; COG2382 Enterochelin esterase and related enzymes; E=2e-33. (548 aa)    
Predicted Functional Partners:
RB6500
Mycocerosate synthase; PMID: 3880746 best DB hits: BLAST: pir:S72705; mycocerosate synthase (EC 2.3.1.111) - Mycobacterium; E=0.0 pir:H70819; probable polyketide synthase - Mycobacterium tuberculosis; E=0.0 gb:AAF62883.1; AF217189_6 (AF217189) epoD [Sorangium cellulosum]; E=1e-180 COG: PA2402_3; COG1020 Non-ribosomal peptide synthetase modules and related; E=4e-99 BS_ppsD_3; COG1020 Non-ribosomal peptide synthetase modules and; E=4e-92 PA2424_2; COG1020 Non-ribosomal peptide synthetase modules and related; E=1e-91 PFAM: PF00108; Thiolase, N-terminal domain; E=2.7e-06 PF00109; Beta-keto [...]
  
  
 0.749
RB5189
Hypothetical protein-transmembrane prediction.
  
     0.654
RB11975
Polyketide synthase; PMID: 10662695 PMID: 10649995 best DB hits: BLAST: gb:AAF26921.1; AF210843_18 (AF210843) polyketide synthase [Sorangium; E=0.0 gb:AAF26923.1; AF210843_20 (AF210843) polyketide synthase [Sorangium; E=0.0 gb:AAF62883.1; AF217189_6 (AF217189) epoD [Sorangium cellulosum]; E=0.0 COG: BS_fabD; COG0331 (acyl-carrier-protein) S-malonyltransferase; E=7e-31 PA2965; COG0304 3-oxoacyl-(acyl-carrier-protein) synthase I; E=3e-28 PA5234; COG0604 NADPH:quinone reductase and related Zn-dependent; E=2e-27 PFAM: PF00108; Thiolase, N-terminal domain; E=7.3e-07 PF00109; Beta-ketoacyl s [...]
  
  
 0.597
RB11023
Hypothetical protein.
       0.572
RB11021
PMID: 8843436 best DB hits: BLAST: embl:CAC10293.1; (AL442629) putative ABC transport system ATP; E=3e-49 embl:CAB81857.1; (AL161691) putative ABC-transporter ATP-binding; E=6e-48 embl:CAB89461.1; (AL354048) putative ABC transporter ATP-binding; E=5e-47 COG: AF1469; COG1136 ABC-type (unclassified) transport system, ATPase; E=3e-47 PFAM: PF00485; Phosphoribulokinase / Uridine; E=0.21 PF00005; ABC transporter; E=2.1e-56.
  
    0.495
RB11016
Hypothetical protein-transmembrane region and signal peptide prediction; Best DB hits: PFAM: PF00114; Pilin (bacterial filament); E=0.038.
 
     0.466
RB11015
Hypothetical protein-transmembrane region and signal peptide prediction; Best DB hits: PFAM: PF00114; Pilin (bacterial filament); E=0.038.
 
     0.410
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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