STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
sul1Probable sulfate transporter; PMID: 10984043 best DB hits: BLAST: pir:B70979; hypothetical protein Rv3273 - Mycobacterium tuberculosis; E=2e-36 pir:D83631; probable sulfate transporter PA0103 [imported] -; E=3e-31 ddbj:BAB20551.1; (AB040415) Mig5 [Salmonella enterica serovar; E=9e-24 COG: PA0103; COG0659 Sulfate permease and related transporters (MFS; E=2e-32 DR2238; COG0288 Carbonic anhydrase; E=2e-24 slr0096; COG0659 Sulfate permease and related transporters (MFS; E=4e-15 PFAM: PF00916; Sulfate transporter family; E=1.5e-39 PF00484; Carbonic anhydrase; E=5.9e-12 PF02878; Phosphogluco [...] (768 aa)    
Predicted Functional Partners:
RB4267
A-type carbonic anhydrase; PMID: 11065374 best DB hits: BLAST: ddbj:BAA82053.1; (AB022175) a-type carbonic anhydrase; E=2e-20 pir:F82479; carbonic anhydrase VCA0274 [imported] - Vibrio cholerae; E=6e-18 swissprot:P94170; CAH_ANASP CARBONIC ANHYDRASE PRECURSOR; E=4e-16 COG: VCA0274; COG3338 Carbonic anhydrase; E=6e-19 PFAM: PF00194; Eukaryotic-type carbonic anhy; E=4.1e-15.
  
 
 0.934
RB5961
Best DB hits: BLAST: pir:B75318; ferripyochelin-binding protein - Deinococcus radiodurans; E=1e-38 gb:AAB88579.1; (M82832) unknown [Pseudomonas aeruginosa]; E=2e-34 swissprot:P40882; Y1F3_PSEAE HYPOTHETICAL PROTEIN PA3753 -----; E=2e-34 COG: DR2089; COG0663 Carbonic anhydrases/acetyltransferases, isoleucine; E=1e-39 PFAM: PF00132; Bacterial transferase hexapeptide (f; E=0.67.
   
 
 0.868
RB11975
Polyketide synthase; PMID: 10662695 PMID: 10649995 best DB hits: BLAST: gb:AAF26921.1; AF210843_18 (AF210843) polyketide synthase [Sorangium; E=0.0 gb:AAF26923.1; AF210843_20 (AF210843) polyketide synthase [Sorangium; E=0.0 gb:AAF62883.1; AF217189_6 (AF217189) epoD [Sorangium cellulosum]; E=0.0 COG: BS_fabD; COG0331 (acyl-carrier-protein) S-malonyltransferase; E=7e-31 PA2965; COG0304 3-oxoacyl-(acyl-carrier-protein) synthase I; E=3e-28 PA5234; COG0604 NADPH:quinone reductase and related Zn-dependent; E=2e-27 PFAM: PF00108; Thiolase, N-terminal domain; E=7.3e-07 PF00109; Beta-ketoacyl s [...]
  
 
 0.837
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
  
  
 0.767
bacA
Bacitracin resistance protein (BacA); Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family.
     
 0.744
RB10314
Conserved hypothetical protein; PMID: 9537320 best DB hits: BLAST: pir:G70374; hypothetical protein aq_863 - Aquifex aeolicus -----; E=6e-49 pir:H82182; conserved hypothetical protein VC1582 [imported] - Vibrio; E=8e-46 pir:E69745; hypothetical protein ybcD - Bacillus subtilis -----; E=1e-39 COG: aq_863; COG3002 Uncharacterized BCR; E=6e-50 PFAM: PF02873; UDP-N-acetylenolpyruvoylglucosamine; E=0.038; Belongs to the UPF0753 family.
 
    0.718
ndhF
NADH subunit 5; PMID: 3035337 best DB hits: BLAST: gb:AAG09461.1; AF217811_11 (AF217811) NADH subunit 5 [Tupaia; E=3e-29 swissprot:P50368; NU5M_SCHCO NADH-UBIQUINONE OXIDOREDUCTASE CHAIN; E=4e-29 embl:CAA50887.1; (X72004) NADH-ubiquinone oxidoreductase subunit; E=1e-28 COG: slr0844; COG1009 NADH:ubiquinone oxidoreductase subunit 5 (chain L); E=3e-29 PAB1402; COG0651 Formate hydrogenlyase subunit 3; E=4e-17 sll1732; COG1009 NADH:ubiquinone oxidoreductase subunit 5 (chain L); E=1e-16 PFAM: PF00662; NADH-Ubiquinone oxidoreductase; E=0.41 PF00361; NADH-Ubiquinone/plastoquinone (; E=1.2e-36.
 
  
 0.684
RB1178
Probable integrase; PMID: 7492116 best DB hits: BLAST: ddbj:BAB12601.1; (AP002527) The peptide is not translated beyond; E=1e-04 gb:AAK01408.1; AF324211_1 (AF324211) site-specific tyrosine; E=2e-04 pir:C82476; site-specific recombinase IntI4 VCA0291 [imported] -; E=2e-04 COG: VCA0291; COG0582 Integrase; E=3e-05 PFAM: PF00589; Phage integrase family; E=0.02.
   
  
 0.653
RB1192
Integrase; PMID: 9082984 best DB hits: BLAST: swissprot:P55632; Y4QK_RHISN PUTATIVE INTEGRASERECOMBINASE Y4QK; E=5e-39 swissprot:P55429; Y4EF_RHISN PUTATIVE INTEGRASERECOMBINASE Y4EF; E=1e-32 prf:2115270D; integrase [Weeksella zoohelcum]; E=1e-22 COG: PAB0255; COG0582 Integrase; E=3e-21 PFAM: PF02899; Phage integrase, N-terminal S; E=0.087 PF00589; Phage integrase family; E=8e-31; Belongs to the 'phage' integrase family.
   
  
 0.653
RB2558
Integrase; PMID: 9023666 best DB hits: BLAST: swissprot:P55632; Y4QK_RHISN PUTATIVE INTEGRASERECOMBINASE Y4QK; E=3e-39 swissprot:P55429; Y4EF_RHISN PUTATIVE INTEGRASERECOMBINASE Y4EF; E=1e-32 prf:2115270D; integrase [Weeksella zoohelcum]; E=6e-23 COG: PAB0255; COG0582 Integrase; E=1e-20 PFAM: PF02899; Phage integrase, N-terminal S; E=0.3 PF00589; Phage integrase family; E=8e-31; Belongs to the 'phage' integrase family.
   
  
 0.653
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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