STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
nhaPPutative Na(+)/H(+) exchanger ycgO; PMID: 9507001 PMID: 9278382 PMID: 9537504 best DB hits: BLAST: pir:C82043; conserved hypothetical protein VC2703 [imported] -; E=2e-76 swissprot:P76007; YCGO_ECOLI PUTATIVE NA(+)H(+) EXCHANGER YCGO; E=5e-74 ddbj:BAB07757.1; (AP001520) Na+H+ antiporter [Bacillus; E=2e-71 COG: VC2703_1; COG0025 NhaP-type Na+/H+ and K+/H+ antiporters; E=1e-64 VC2703_2; COG3263 Uncharacterized BCR; E=1e-04 sll0556_1; COG0025 NhaP-type Na+/H+ and K+/H+ antiporters; E=1e-04 PFAM: PF00999; Sodium/hydrogen exchanger fami; E=2.8e-60 PF02080; Potassium channel; E=5e-05. (589 aa)    
Predicted Functional Partners:
RB792
Probable Na+/H+ antiporter; PMID: 9537504 best DB hits: BLAST: pir:H83377; probable transporter PA2135 [imported] - Pseudomonas; E=2e-35 ddbj:BAB07757.1; (AP001520) Na+H+ antiporter [Bacillus; E=0.002 gb:AAF72041.1; AF128238_1 (AF128238) Na+H+ antiporter Cnh1; E=0.003 COG: PA2135; COG0025 NhaP-type Na+/H+ and K+/H+ antiporters; E=1e-36 PFAM: PF00999; Sodium/hydrogen exchanger fami; E=1.3e-14.
  
   
 0.750
RB11070
Hypothetical protein.
       0.564
RB11067
Hypothetical protein-transmembrane region and signal peptide prediction.
       0.440
RB11331
Probable glutathione-regulated potassium-efflux system protein KefB; PMID: 2046548 PMID: 8412700 best DB hits: BLAST: pir:T35377; probable membrane protein - Streptomyces coelicolor; E=4e-08 pir:S76244; hypothetical protein - Synechocystis sp. (strain PCC; E=6e-06 pir:S76018; hypothetical protein - Synechocystis sp. (strain PCC; E=3e-04 COG: sll0261; COG1226 Kef-type K+ transport systems, predicted; E=6e-07 DR2336; COG1226 Kef-type K+ transport systems, predicted NAD-binding; E=4e-04 MJ0138.1; COG1226 Kef-type K+ transport systems, predicted; E=7e-04 PFAM: PF01408; Oxidoreductase famil [...]
 
   
 0.430
trkH
PMID: 7896723 best DB hits: BLAST: gb:AAB90400.1; (AE001046) TRK potassium uptake system protein; E=8e-61 pir:G82037; potassium uptake protein TrkH VC2756 [imported] - Vibrio; E=4e-49 swissprot:P44843; TRKH_HAEIN TRK SYSTEM POTASSIUM UPTAKE PROTEIN; E=1e-46 COG: AF0839; COG0168 Trk-type K+ transport systems, membrane components; E=8e-62 NMB0661_2; COG0168 Trk-type K+ transport systems, membrane; E=1e-36 PA3210; COG0168 Trk-type K+ transport systems, membrane components; E=1e-36 PFAM: PF02386; Sodium transport protein; E=1.1e-54.
 
   
 0.422
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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