Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RB11077Conserved hypothetical protein; PMID: 10761919 best DB hits: BLAST: pir:D81775; conserved hypothetical protein NMA2048 [imported] -; E=3e-17 pir:F81198; conserved hypothetical protein NMB0437 [imported] -; E=4e-17 gb:AAC61685.1; (AF052517) CDG1D [Acetobacter xylinus]; E=1e-15 COG: NMB0437; COG1959 Predicted transcriptional regulator; E=4e-18 PFAM: PF02082; Uncharacterized protein family UPF00; E=1.3e-33. (155 aa)    
Predicted Functional Partners:
fhp
HMP; PMID: 8557026 PMID: 1594608 best DB hits: BLAST: ddbj:BAA83959.1; (AB024563) HMP [Bacillus halodurans] -----; E=7e-96 swissprot:P39662; HMPA_ALCEU FLAVOHEMOPROTEIN (HEMOGLOBIN-LIKE; E=8e-92 pir:A82854; flavohemoprotein XF0053 [imported] - Xylella fastidiosa; E=8e-83 COG: BH1058_2; COG1018 Flavodoxin reductases (ferredoxin-NADPH; E=1e-53 BH1058_1; COG1017 Hemoglobin-like flavoprotein; E=1e-35 hmp_2; COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases); E=6e-34 PFAM: PF00042; Globin; E=7e-19 PF00970; Oxidoreductase FAD-binding dom; E=2.9e-08 PF01794; Ferric reductase like tra [...]
 
   
 0.659
RB6350
PMID: 10984043 best DB hits: BLAST: pir:E83450; probable cytochrome oxidase subunit (cbb3-type) PA1557; E=1e-134 pir:E81050; cytochrome-c oxidase (EC 1.9.3.1) fixN chain NMB1725; E=1e-132 pir:C83452; probable cytochrome oxidase subunit (cbb3-type) PA1554; E=1e-129 COG: PA1557; COG3278 Cbb3-type cytochrome oxidase, subunit 1; E=1e-135 NMB1724; COG2993 Cbb3-type cytochrome oxidase, cytochrome c subunit; E=8e-38 slr1137; COG0843 Heme/copper-type cytochrome/quinol oxidases,; E=6e-12 PFAM: PF00115; Cytochrome C and Quinol oxidase poly; E=3.4e-65 PF02433; Cytochrome C oxidase, mono-heme subu [...]
  
    0.591
RB2238
Flavohemoprotein; PMID: 8125952 best DB hits: BLAST: swissprot:P39662; HMPA_ALCEU FLAVOHEMOPROTEIN (HEMOGLOBIN-LIKE; E=7e-29 swissprot:P49852; HMPA_BACSU FLAVOHEMOPROTEIN (HEMOGLOBIN-LIKE; E=2e-26 swissprot:P26353; HMPA_SALTY FLAVOHEMOPROTEIN (HEMOGLOBIN-LIKE; E=2e-26 COG: BS_hmp_2; COG1018 Flavodoxin reductases (ferredoxin-NADPH; E=1e-27 hmp_2; COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases); E=5e-25 BH1058_2; COG1018 Flavodoxin reductases (ferredoxin-NADPH; E=5e-23 PFAM: PF00970; Oxidoreductase FAD-binding doma; E=3.5e-24 PF01794; Ferric reductase like transmemb; E=0.76 P [...]
 
  
 0.582
RB11079
Hypothetical protein.
       0.569
RB11080
Hypothetical protein.
       0.569
RB11582
Cysteine desulfurase; PMID: 10908675 PMID: 7496536 PMID: 8482384 best DB hits: BLAST: pir:A71960; probable nitrogenase cofactor synthesis protein nifS -; E=1e-50 pir:D64547; iron-sulfur cofactor synthesis protein - Helicobacter; E=2e-50 swissprot:Q43884; NIFS_ANAAZ NIFS PROTEIN ----- gb: AAA87249.1; E=6e-49 COG: jhp0206; COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase; E=1e-51 PFAM: PF00266; Aminotransferase class-V; E=1.6e-60.
  
  
 0.554
nifS-3
Cysteine desulfurase NifS; PMID: 10930739 PMID: 2553733 best DB hits: BLAST: gb:AAG01802.1; AF276772_1 (AF276772) cysteine desulfurase NifS; E=4e-53 swissprot:P12623; NIFS_ANASP NIFS PROTEIN ----- pir: C34443; E=2e-50 swissprot:Q43884; NIFS_ANAAZ NIFS PROTEIN ----- gb: AAA87249.1; E=3e-50 COG: yfhO; COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase; E=3e-51 PFAM: PF00266; Aminotransferase class-V; E=7.9e-47.
  
  
 0.554
nifS-4
NifS-like aminotranfserase-putative cysteine desulfurase; PMID: 8663056 PMID: 10600118 PMID: iscS best DB hits: BLAST: pir:E81852; NifS-like aminotranfserase NMA1594 [imported] -; E=1e-63 gb:AAF62329.1; (AE002486) nifS protein [Neisseria meningitidis; E=9e-63 pir:A71652; iron-sulfur cofactor synthesis protein RP486 -; E=1e-60 COG: NMB1379; COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase; E=8e-64 PFAM: PF00266; Aminotransferase class-V; E=3.4e-70.
  
  
 0.554
nifU
Nitrogen fixation protein NifU; PMID: 11016950 best DB hits: BLAST: gb:AAG20546.1; (AE005125) nitrogen fixation protein; NifU; E=2e-22 ddbj:BAB07187.1; (AP001518) nitrogen fixation protein [Bacillus; E=4e-16 swissprot:Q9X192; NIFU_THEMA NIFU-LIKE PROTEIN ----- pir:; E=4e-15 COG: VNG2472G; COG0822 NifU homologs involved in Fe-S cluster formation; E=2e-23 PFAM: PF01592; NifU-like N terminal domain; E=1e-22.
 
  
 0.548
RB11081
Hypothetical protein-transmembrane prediction.
       0.486
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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