STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cyaAAdenylate cyclase homolog; PMID: 10952301 best DB hits: BLAST: pir:T17197; adenylate cyclase homolog - Spirulina platensis -----; E=5e-17 pir:G82244; response regulator VC1087 [imported] - Vibrio cholerae; E=1e-15 ddbj:BAA14000.1; (D89625) adenylate cyclase [Anabaena sp.]; E=6e-14 COG: VC1087_1; COG0784 CheY-like receiver domains; E=2e-16 PA2881; COG2204 AAA superfamily ATPases with N-terminal receiver; E=2e-12 VC1086_1; COG0784 CheY-like receiver domains; E=4e-11 PFAM: PF00072; Response regulator receiver doma; E=8e-19. (382 aa)    
Predicted Functional Partners:
RB11091
Probable two-component sensor; PMID: 9045826 PMID: 10564511 best DB hits: BLAST: pir:F83324; probable two-component sensor PA2571 [imported] -; E=5e-36 pir:D82244; sensory box sensor histidine kinase VC1084 [imported] -; E=1e-35 pir:C82425; sensor histide kinase VCA0719 [imported] - Vibrio; E=2e-34 COG: PA2571; COG0642 Sensory transduction histidine kinases; E=5e-37 PFAM: PF00989; PAS domain; E=1.1e-06 PF00512; His Kinase A (phosphoacceptor) doma; E=0.001 PF02518; Histidine kinase-, DNA gyrase B-, p; E=2.9e-30.
 
 
 
 0.914
RB4511
Sensory transduction histidine kinase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
 
 
 0.883
RB10924
Probable sensor/response regulator hybrid; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
 
 
 0.881
flgE
Flagellar hook protein FlgE; PMID: 10368149 best DB hits: BLAST: gb:AAD24206.1; AF049342_4 (AF049342) flagellar hook protein FlgE; E=8e-22 gb:AAA61738.1; (U19712) flagellar hook polypeptide [Borrelia; E=1e-21 gb:AAA91361.1; (U12870) flagellar distal rod protein [Borrelia; E=3e-21 COG: BB0283; COG1749 Flagellar basal body and hook proteins; E=5e-22 PFAM: PF00460; Flagella basal body rod protein; E=3.7e-10.
  
  
 0.799
RB7308
Sensory box sensor histidine kinase; PMID: 20406833 best DB hits: BLAST: pir:H83285; probable two-component sensor PA2882 [imported] -; E=2e-36 pir:F83324; probable two-component sensor PA2571 [imported] -; E=3e-36 pir:D82244; sensory box sensor histidine kinase VC1084 [imported] -; E=7e-34 COG: PA2882; COG0642 Sensory transduction histidine kinases; E=2e-37 PFAM: PF00785; PAC motif; E=5.1e-05 PF00512; His Kinase A (phosphoacceptor); E=0.0012 PF02518; Histidine kinase-, DNA gyrase B; E=5.2e-32.
 
 
 
 0.783
RB3779
Putative histidine protein kinase; PMID: 10564511 best DB hits: BLAST: gb:AAD47812.1; (AF163841) putative histidine protein kinase; E=7e-40 pir:D82244; sensory box sensor histidine kinase VC1084 [imported] -; E=2e-38 pir:F83324; probable two-component sensor PA2571 [imported] -; E=2e-35 COG: VC1084; COG0642 Sensory transduction histidine kinases; E=2e-39 slr1759_2; COG2202 PAS/PAC domain; E=1e-18 BS_ykrQ_3; COG0642 Sensory transduction histidine kinases; E=1e-18 PFAM: PF00989; PAS domain; E=0.0067 PF00785; PAC motif; E=3.7e-09 PF00989; PAS domain; E=0.17.
 
 
 
 0.772
RB11095
Hypothetical protein-transmembrane prediction.
       0.617
RB11668
Sensor kinase homolog; PMID: 3595559 best DB hits: BLAST: gb:AAF13178.1; AF181079_1 (AF181079) sensor kinase homolog; E=2e-28 pir:D83491; probable sensorresponse regulator hybrid PA1243; E=4e-28 gb:AAG00949.1; AF273679_3 (AF273679) FixL [Rhizobium etli]; E=3e-27 COG: PA1243; COG0642 Sensory transduction histidine kinases; E=4e-29 PFAM: PF00512; His Kinase A (phosphoacceptor) doma; E=5.2e-12 PF02518; Histidine kinase-, DNA gyrase B-, p; E=3.1e-28.
  
 
   0.564
RB641
Sensory histidine protein kinase; Best DB hits: BLAST: pir:G82753; two-component system, sensor protein XF0853 [imported] -; E=2e-41 gb:AAA98756.1; (L29642) sensor kinase [Pseudomonas fluorescens]; E=8e-39 pir:A82300; sensory box sensor histidine kinaseresponse regulator; E=4e-34 COG: XF0853; COG0642 Sensory transduction histidine kinases; E=2e-42 sll0779_1; COG2202 PAS/PAC domain; E=1e-23 VCA0736_1; COG0642 Sensory transduction histidine kinases; E=1e-23 PFAM: PF00785; PAC motif; E=8.5e-08 PF00989; PAS domain; E=0.013 PF00785; PAC motif; E=0.1.
 
 
 0.495
RB3373
PMID: 9098081 best DB hits: BLAST: pir:T28655; receptor-like histidine kinase BpdS - Rhodococcus sp; E=1e-60 pir:T30898; receptor-like histidine kinase - Rhodococcus erythropolis; E=1e-60 pir:S75136; sensory transduction histidine kinase slr2104 -; E=9e-58 COG: VC1349_2; COG0642 Sensory transduction histidine kinases; E=1e-41 PFAM: PF00069; Protein kinase domain; E=8.1e-08 PF00515; TPR Domain; E=0.026 PF00512; His Kinase A (phosphoacceptor); E=1.4e-21.
 
 
 0.476
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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