STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RB11136Serine/threonine protein kinase; PMID: 1835671 best DB hits: BLAST: pir:T36717; probable serinethreonine protein kinase - Streptomyces; E=1e-31 embl:CAA10713.1; (AJ132604) hypothetical protein [Lactococcus; E=1e-31 pir:H69878; probable protein kinase (EC 2.7.1.-) yloP - Bacillus; E=3e-31 COG: BS_yloP_1; COG0515 Serine/threonine protein kinases; E=3e-32 PFAM: PF00069; Protein kinase domain; E=9.9e-29 PF00515; TPR Domain; E=0.0026. (912 aa)    
Predicted Functional Partners:
Pph1
Probable protein phosphatase 1; PMID: 11298281 best DB hits: BLAST: gb:AAF81068.1; AF223364_3 (AF223364) protein phosphatase 1; E=9e-32 pir:E71538; hypothetical protein CT259 - Chlamydia trachomatis; E=4e-28 pir:H75265; conserved hypothetical protein - Deinococcus radiodurans; E=5e-28 COG: CT259; COG0631 Protein serine/threonine phosphatases; E=4e-29 PFAM: PF00481; Protein phosphatase 2C; E=4.9e-09.
  
   0.803
RB3245
Protein phosphatase 1; PMID: 11298281 best DB hits: BLAST: gb:AAF81068.1; AF223364_3 (AF223364) protein phosphatase 1; E=3e-27 pir:E71538; hypothetical protein CT259 - Chlamydia trachomatis; E=5e-26 embl:CAA10712.1; (AJ132604) pppL protein [Lactococcus lactis]; E=2e-25 COG: CT259; COG0631 Protein serine/threonine phosphatases; E=4e-27 PFAM: PF00481; Protein phosphatase 2C; E=1.2e-09.
  
   0.801
rpoE-2
Probable RNA polymerase sigma-E factor; PMID: 11248100 PMID: 7768826 PMID: 7889934 best DB hits: BLAST: gb:AAK03873.1; (AE006215) RpoE [Pasteurella multocida]; E=7e-07 swissprot:P44790; RPOE_HAEIN RNA POLYMERASE SIGMA-E FACTOR; E=2e-06 pir:H82073; RNA polymerase sigma-E factor VC2467 [imported] - Vibrio; E=5e-06 COG: HI0628; COG1595 DNA-directed RNA polymerase specialized sigma; E=2e-07 PFAM: PF00776; Sigma-70 factor (ECF subfamily); E=0.4.
   
   0.784
RB10333
Protein kinase homolog; Best DB hits: BLAST: pir:T42076; protein kinase homolog - Streptomyces coelicolor -----; E=5e-18 pir:T42077; protein kinase homolog - Streptomyces coelicolor -----; E=1e-16 pir:T35491; probable serinethreonine-specific protein kinase pkaF -; E=1e-16 COG: Rv0014c_1; COG0515 Serine/threonine protein kinases; E=3e-15 PFAM: PF00069; Protein kinase domain; E=3.2e-06.
  
     0.775
RB11137
Hypothetical protein.
       0.773
RB11133
Matrix metalloproteinase 1; PMID: 10964925 PMID: 7657606 best DB hits: BLAST: gb:AAF47255.1; (AE003464) CG4859 gene product [Drosophila; E=3e-18 gb:AAG33131.1; AF271666_1 (AF271666) matrix metalloproteinase 1; E=3e-18 embl:CAA78248.1; (Z12604) stromelysin-3 [Mus musculus]; E=8e-16 PFAM: PF00404; Dockerin type I repeat; E=0.0079.
       0.509
RB11142
Hypothetical protein-signal peptide prediction; Best DB hits: PFAM: PF01011; PQQ enzyme repeat; E=0.34.
       0.434
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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