Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
yjgBHypothetical zinc-type alcohol dehydrogenase-like protein yjgB; PMID: 87304248 PMID: 92277668 best DB hits: BLAST: pir:S76928; probable aryl alcohol dehydrogenase (EC 1.1.1.-) -; E=1e-94 pir:S56495; probable aryl alcohol dehydrogenase (EC 1.1.1.-) yjgB -; E=6e-71 swissprot:P27250; YJGB_ECOLI HYPOTHETICAL ZINC-TYPE ALCOHOL; E=6e-71 COG: slr1192; COG1064 Zn-dependent alcohol dehydrogenases; E=9e-96 PFAM: PF00899; ThiF family; E=0.48 PF02826; D-isomer specific 2-hydroxyacid; E=0.48 PF00107; Zinc-binding dehydrogenases; E=5.9e-85. (336 aa)    
Predicted Functional Partners:
RB10172
Aldehyde dehydrogenase; PMID: 9369242 best DB hits: BLAST: gb:AAA64636.1; (U07235) aldehyde dehydrogenase [Mus musculus]; E=1e-163 gb:AAA51693.1; (M20456) aldehyde dehydrogenase [Homo sapiens]; E=1e-163 pir:DEHUE2; aldehyde dehydrogenase (NAD+) (EC 1.2.1.3) 2 precursor,; E=1e-162 COG: BH0539; COG1012 NAD-dependent aldehyde dehydrogenases; E=1e-156 PFAM: PF00171; Aldehyde dehydrogenase family; E=1.5e-240; Belongs to the aldehyde dehydrogenase family.
  
 0.913
RB683
Aldehyde dehydrogenase; PMID: 7484410 best DB hits: BLAST: gb:AAF52769.1; (AE003624) CG3752 gene product [Drosophila; E=5e-73 ddbj:BAA34785.1; (AB015226) RALDH2 [Homo sapiens]; E=2e-72 swissprot:O94788; DHAS_HUMAN RETINALDEHYDE-SPECIFIC DEHYDROGENASE; E=2e-72 COG: YOR374w; COG1012 NAD-dependent aldehyde dehydrogenases; E=2e-71 PFAM: PF00171; Aldehyde dehydrogenase family; E=7e-156.
  
 0.913
RB12303
Best DB hits: BLAST: pir:H69064; serinethreonine protein kinase related protein -; E=3e-04 gb:AAG20856.1; (AE005154) Vng6189h [Halobacterium sp. NRC-1]; E=0.007 gb:AAF16758.1; AC010155_11 (AC010155) F3M18.23 [Arabidopsis; E=0.014 COG: MTH1485; COG1520 Uncharacterized proteins of WD40-like repeat family; E=3e-05 PFAM: PF01011; PQQ enzyme repeat; E=0.0074.
   
 
  0.900
RB10805
Putative iron alcohol dehydrogenase; PMID: 88038383 best DB hits: BLAST: swissprot:Q09669; ADHF_SCHPO PUTATIVE IRON ALCOHOL DEHYDROGENASE; E=5e-46 gb:AAD43989.1; U59485_16 (U59485) AttL [Agrobacterium tumefaciens]; E=5e-45 gb:AAG58733.1; AE005585_7 (AE005585) putative oxidoreductase; E=6e-42 COG: yiaY; COG1454 Alcohol dehydrogenase IV; E=3e-42 PFAM: PF00465; Iron-containing alcohol dehydrogenas; E=3.3e-58.
  
 
 0.872
RB6350
PMID: 10984043 best DB hits: BLAST: pir:E83450; probable cytochrome oxidase subunit (cbb3-type) PA1557; E=1e-134 pir:E81050; cytochrome-c oxidase (EC 1.9.3.1) fixN chain NMB1725; E=1e-132 pir:C83452; probable cytochrome oxidase subunit (cbb3-type) PA1554; E=1e-129 COG: PA1557; COG3278 Cbb3-type cytochrome oxidase, subunit 1; E=1e-135 NMB1724; COG2993 Cbb3-type cytochrome oxidase, cytochrome c subunit; E=8e-38 slr1137; COG0843 Heme/copper-type cytochrome/quinol oxidases,; E=6e-12 PFAM: PF00115; Cytochrome C and Quinol oxidase poly; E=3.4e-65 PF02433; Cytochrome C oxidase, mono-heme subu [...]
  
  
 0.751
ldh
L-lactate dehydrogenase; PMID: 3122782 PMID: 3118900 best DB hits: BLAST: swissprot:P00345; LDH_BACME L-LACTATE DEHYDROGENASE -----pir:; E=3e-49 swissprot:P20619; LDHX_BACPS L-LACTATE DEHYDROGENASE X -----; E=6e-47 swissprot:P16115; LDH_THEMA L-LACTATE DEHYDROGENASE ----- pir:; E=3e-46 COG: TM1867; COG0039 Malate/lactate dehydrogenases; E=2e-47 PFAM: PF00056; lactate/malate dehydrogenase, NA; E=6.7e-46 PF02866; lactate/malate dehydrogenase, al; E=2.4e-36; Belongs to the LDH/MDH superfamily.
   
 
 0.710
ldh-2
L-lactate/malate dehydrogenase; PMID: 8404889 PMID: 3098260 best DB hits: BLAST: swissprot:P16115; LDH_THEMA L-LACTATE DEHYDROGENASE -----pir:; E=2e-51 pdb:1A5Z; Lactate Dehydrogenase From Thermotoga Maritima; E=2e-51 pdb:1LLC; L-Lactate Dehydrogenase (E.C.1.1.1.27) Complex With; E=9e-49 COG: TM1867; COG0039 Malate/lactate dehydrogenases; E=2e-52 PFAM: PF00056; lactate/malate dehydrogenase, NA; E=7.5e-36 PF02866; lactate/malate dehydrogenase, al; E=5e-36; Belongs to the LDH/MDH superfamily.
   
 
 0.710
pta
Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
  
  
 0.677
leuA
3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
    
 
 0.632
RB11150
Xenobiotic reductase B; PMID: 10515912 best DB hits: BLAST: pir:D83102; xenobiotic reductase PA4356 [imported] - Pseudomonas; E=5e-92 ddbj:BAA88211.1; (AB025798) NAD(P)H-dependent 2-cyclohexen-1-one; E=1e-91 gb:AAF02539.1; AF154062_1 (AF154062) xenobiotic reductase B; E=1e-87 COG: PA4356; COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme; E=4e-93 nemA; COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family; E=2e-73 PA2932; COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme; E=3e-70 PFAM: PF00724; NADH:flavin oxidoreductase / NAD; E=5.6e-98.
  
  
 0.597
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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