Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
arsC-2Arsenate reductase; PMID: 8674982 best DB hits: BLAST: pir:C81247; arsenate reductase NMB0005 [imported] - Neisseria; E=8e-26 gb:AAG57605.1; AE005479_3 (AE005479) putative oxidoreductase; E=6e-25 swissprot:P76569; YFGD_ECOLI PROTEIN YFGD ----- pir: F65025; E=6e-25 COG: NMB0005; COG1393 Arsenate reductase and related proteins,; E=8e-27 yfgD; COG1393 Arsenate reductase and related proteins, glutaredoxin; E=7e-26 VC2165; COG1393 Arsenate reductase and related proteins,; E=3e-25; Belongs to the ArsC family. (116 aa)    
Predicted Functional Partners:
arsA-10
ArsA-catalytic subunit of arsenic oxyanion-translocating ATPase; PMID: 9464374 best DB hits: BLAST: gb:AAD51849.1; AF178758_5 (AF178758) ArsA [Sinorhizobium sp. As4]; E=1e-162 swissprot:O50593; ARSA_ACIMU ARSENICAL PUMP-DRIVING ATPASE; E=1e-148 swissprot:P52145; ARA2_ECOLI ARSENICAL PUMP-DRIVING ATPASE; E=1e-147 COG: MJ1142; COG0003 Arsenite transporting ATPase; E=6e-22 PA1462; COG1192 ATPases involved in chromosome partitioning; E=4e-04 PFAM: PF01583; Adenylylsulfate kinase; E=0.42 PF00142; 4Fe-4S iron sulfur cluster bi; E=0.31 PF01695; IstB-like ATP binding protein; E=0.025.
    
 0.640
RB7297
Conserved hypothetical protein; PMID: 20406833 best DB hits: BLAST: pir:D82096; hypothetical protein VC2280 [imported] - Vibrio cholerae; E=1e-25 pir:C82997; hypothetical protein PA5196 [imported] - Pseudomonas; E=6e-13 pir:B82234; hypothetical protein VC1162 [imported] - Vibrio cholerae; E=3e-07.
 
      0.619
RB11156
Probable squalene-hopene cyclase; PMID: 1729216 PMID: 9532806 PMID: 2253626 PMID: 9295270 best DB hits: BLAST: pir:T35404; probable squalene-hopene cyclase - Streptomyces; E=1e-04 pir:A43300; squalene-hopene cyclase (EC 5.4.99.-) - Alicyclobacillus; E=0.008 gb:AAA75452.1; (M73834) squalene-hopene-cyclase [Alicyclobacillus; E=0.008 PFAM: PF01264; Chorismate synthase; E=0.74 PF00432; Prenyltransferase and squalen; E=0.00015.
       0.572
rpoA
DNA-directed RNA polymerase alpha chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
   0.566
rpoA-2
PMID: 9835038 best DB hits: BLAST: swissprot:O50634; RPOA_BACHD DNA-DIRECTED RNA POLYMERASE ALPHA; E=2e-09 swissprot:Q9Z3E7; RPOA_XANCP DNA-DIRECTED RNA POLYMERASE ALPHA; E=4e-09 gb:AAD00325.2; (U79735) RNA polymerase ALPHA subunit [Xanthomonas; E=4e-09 COG: BH0162; COG0202 DNA-directed RNA polymerase alpha subunit/40 kD; E=2e-10 PFAM: PF00515; TPR Domain; E=0.87 PF01000; Bacterial RNA polymerase, alpha; E=6.5e-12.
    
   0.566
rpoA-3
PMID: 3093467 best DB hits: BLAST: swissprot:P20429; RPOA_BACSU DNA-DIRECTED RNA POLYMERASE ALPHA; E=1e-07 gb:AAA81287.1; (U30821) alpha subunit of RNA polymerase; E=5e-07 swissprot:O50634; RPOA_BACHD DNA-DIRECTED RNA POLYMERASE ALPHA; E=1e-06 COG: BS_rpoA; COG0202 DNA-directed RNA polymerase alpha subunit/40 kD; E=1e-08 PFAM: PF01000; Bacterial RNA polymerase, alpha; E=8.2e-15.
    
   0.566
RB11154
PMID: 10984043 best DB hits: BLAST: pir:A83330; probable RND efflux membrane fusion protein precursor; E=2e-06 gb:AAG57137.1; AE005434_1 (AE005434) putative membrane protein; E=2e-06 ddbj:BAA15928.1; (D90845) Membrane fusion protein MtrC precursor; E=4e-06 COG: PA2528; COG0845 Membrane-fusion protein; E=2e-07 PA3892; COG1566 Multidrug resistance efflux pump; E=1e-05 VC0628; COG0845 Membrane-fusion protein; E=4e-05 PFAM: PF00529; HlyD family secretion protein; E=4.2e-07; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
     
 0.543
RB11160
Conserved hypothetical protein; PMID: 11337471 best DB hits: BLAST: gb:AAK04894.1; AE006313_1 (AE006313) HYPOTHETICAL PROTEIN; E=0.051 pir:T02333; hypothetical protein F13P17.29 - Arabidopsis thaliana; E=0.093 pir:T34378; hypothetical protein T25G12.7 - Caenorhabditis elegans; E=0.095 PFAM: PF01118; Semialdehyde dehydrogenase, NA; E=0.095.
       0.541
RB11162
Hypothetical protein-transmembrane prediction.
       0.541
czcA
PMID: 2678100 best DB hits: BLAST: pir:H82300; probable multidrug resistance protein VC0629 [imported] -; E=3e-51 pir:S76433; cation efflux system protein czcA-2 - Synechocystis sp; E=4e-42 pir:G64595; acriflavine resistance protein - Helicobacter pylori; E=4e-41 COG: VC0629; COG0841 Cation/multidrug efflux pump; E=3e-52 PFAM: PF00873; AcrB/AcrD/AcrF family; E=1e-43; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
     
 0.540
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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