Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
merRPMID: 10567266 best DB hits: BLAST: pir:D75273; transcription regulator, MerR family - Deinococcus; E=9e-08 embl:CAB61592.1; (AL133210) putative DNA polymerase III beta; E=1e-05 embl:CAB88450.1; (AL353815) putative merR-family transcriptional; E=1e-05 COG: DR2448; COG0789 Predicted transcriptional regulators; E=8e-09. (246 aa)    
Predicted Functional Partners:
rpoB
DNA-directed RNA polymerase beta chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.926
rpoC
DNA-directed RNA polymerase beta chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.902
rpoZ
Hypothetical protein; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
   
   0.899
rpoA-2
PMID: 9835038 best DB hits: BLAST: swissprot:O50634; RPOA_BACHD DNA-DIRECTED RNA POLYMERASE ALPHA; E=2e-09 swissprot:Q9Z3E7; RPOA_XANCP DNA-DIRECTED RNA POLYMERASE ALPHA; E=4e-09 gb:AAD00325.2; (U79735) RNA polymerase ALPHA subunit [Xanthomonas; E=4e-09 COG: BH0162; COG0202 DNA-directed RNA polymerase alpha subunit/40 kD; E=2e-10 PFAM: PF00515; TPR Domain; E=0.87 PF01000; Bacterial RNA polymerase, alpha; E=6.5e-12.
   
   0.857
rpoA
DNA-directed RNA polymerase alpha chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
   0.847
rpoA-3
PMID: 3093467 best DB hits: BLAST: swissprot:P20429; RPOA_BACSU DNA-DIRECTED RNA POLYMERASE ALPHA; E=1e-07 gb:AAA81287.1; (U30821) alpha subunit of RNA polymerase; E=5e-07 swissprot:O50634; RPOA_BACHD DNA-DIRECTED RNA POLYMERASE ALPHA; E=1e-06 COG: BS_rpoA; COG0202 DNA-directed RNA polymerase alpha subunit/40 kD; E=1e-08 PFAM: PF01000; Bacterial RNA polymerase, alpha; E=8.2e-15.
    
   0.847
rpdD
RNA polymerase sigma factor rpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
   
 
 0.819
rpoD
Probable RNA polymerase sigma 70; PMID: 10548737 best DB hits: BLAST: ddbj:BAA84590.1; (AB003084) RNA polymerase sigma 70 [Helicobacter; E=1e-14 swissprot:Q9ZMY3; RPSD_HELPJ RNA POLYMERASE SIGMA FACTOR RPOD; E=2e-14 gb:AAB81010.1; (U83703) RNA polymerase principal sigma factor; E=2e-14 COG: jhp0081; COG0568 DNA-directed RNA polymerase sigma subunits; E=1e-15 PFAM: PF00140; Sigma-70 factor; E=8.8e-19.
   
 
 0.819
rpoS
RNA polymerase sigma factor rpoS; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
   
 
 0.819
sigA
Transcription initiation factor sigma 70; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
   
 
 0.819
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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