STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
rcp1Response regulator rcp1; PMID: 7699720 PMID: 9278513 best DB hits: BLAST: embl:CAB62661.1; (AL133422) hypothetical protein SCM1.03c; E=8e-33 pir:D75276; response regulator - Deinococcus radiodurans (strain R1); E=1e-31 swissprot:Q55169; RCP1_SYNY3 RESPONSE REGULATOR RCP1 -----; E=1e-25 COG: DR2420; COG0784 CheY-like receiver domains; E=1e-32 slr0115; COG0745 Response regulators consisting of a CheY-like; E=2e-09 sll0039; COG0784 CheY-like receiver domains; E=6e-09 PFAM: PF00072; Response regulator receiver doma; E=6.5e-19. (146 aa)    
Predicted Functional Partners:
cph1
Light-regulated histidine kinase 1; PMID: 10567266 best DB hits: BLAST: pir:C75276; sensory box sensor histidine kinase - Deinococcus; E=8e-45 swissprot:Q55168; PHY1_SYNY3 PHYTOCHROME-LIKE PROTEIN CPH1; E=1e-41 embl:CAB62662.1; (AL133422) putative two-component sensor; E=2e-41 COG: DR2419_2; COG0642 Sensory transduction histidine kinases; E=8e-46 PFAM: PF00512; His Kinase A (phosphoacceptor) doma; E=1e-12 PF02518; Histidine kinase-, DNA gyrase B-, p; E=3.5e-35.
 
 
   0.952
RB4511
Sensory transduction histidine kinase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
 
 
 0.931
RB10924
Probable sensor/response regulator hybrid; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
 
 
 0.924
RB641
Sensory histidine protein kinase; Best DB hits: BLAST: pir:G82753; two-component system, sensor protein XF0853 [imported] -; E=2e-41 gb:AAA98756.1; (L29642) sensor kinase [Pseudomonas fluorescens]; E=8e-39 pir:A82300; sensory box sensor histidine kinaseresponse regulator; E=4e-34 COG: XF0853; COG0642 Sensory transduction histidine kinases; E=2e-42 sll0779_1; COG2202 PAS/PAC domain; E=1e-23 VCA0736_1; COG0642 Sensory transduction histidine kinases; E=1e-23 PFAM: PF00785; PAC motif; E=8.5e-08 PF00989; PAS domain; E=0.013 PF00785; PAC motif; E=0.1.
 
 
 0.889
RB9418
Signal-transducing histidine kinase; Best DB hits: BLAST: swissprot:Q9R6X3; PHYB_ANASP CYANOBACTERIAL PHYTOCHROME B -----; E=5e-32 gb:AAB89763.1; (AE001000) signal-transducing histidine kinase; E=7e-28 pir:C75276; sensory box sensor histidine kinase - Deinococcus; E=5e-25 COG: DR2419_2; COG0642 Sensory transduction histidine kinases; E=5e-26 PFAM: PF00989; PAS domain; E=1.5e-06 PF00785; PAC motif; E=0.00034 PF00512; His Kinase A (phosphoacceptor) doma; E=1.3e-11.
 
 
 0.865
RB10488
PMID: 20572072 best DB hits: BLAST: pir:S75136; sensory transduction histidine kinase slr2104 -; E=3e-67 pir:E83443; probable sensorresponse regulator hybrid PA1611; E=2e-64 pir:H82211; sensory box sensor histidine kinaseresponse regulator; E=8e-61 COG: VC1349_2; COG0642 Sensory transduction histidine kinases; E=7e-62 PFAM: PF00785; PAC motif; E=0.00076 PF00512; His Kinase A (phosphoacceptor) d; E=1.6e-28 PF02518; Histidine kinase-, DNA gyrase B-; E=1.6e-42.
 
 
 0.864
RB2872
Signal-transducing histidine kinase; PMID: 9278513 best DB hits: BLAST: gb:AAB89763.1; (AE001000) signal-transducing histidine kinase; E=3e-31 swissprot:Q9LCC2; PHYA_ANASP CYANOBACTERIAL PHYTOCHROME A -----; E=3e-28 swissprot:Q55168; PHY1_SYNY3 PHYTOCHROME-LIKE PROTEIN CPH1; E=1e-26 COG: slr0473_3; COG0642 Sensory transduction histidine kinases; E=1e-27 PFAM: PF00785; PAC motif; E=9.9e-06 PF00989; PAS domain; E=1.1e-07 PF00785; PAC motif; E=0.058.
 
 
 0.851
flgE
Flagellar hook protein FlgE; PMID: 10368149 best DB hits: BLAST: gb:AAD24206.1; AF049342_4 (AF049342) flagellar hook protein FlgE; E=8e-22 gb:AAA61738.1; (U19712) flagellar hook polypeptide [Borrelia; E=1e-21 gb:AAA91361.1; (U12870) flagellar distal rod protein [Borrelia; E=3e-21 COG: BB0283; COG1749 Flagellar basal body and hook proteins; E=5e-22 PFAM: PF00460; Flagella basal body rod protein; E=3.7e-10.
  
 
 0.832
phyB
Cyanobacterial phytochrome B; PMID: 11759840 best DB hits: BLAST: swissprot:Q9R6X3; PHYB_ANASP CYANOBACTERIAL PHYTOCHROME B -----; E=3e-32 gb:AAB89763.1; (AE001000) signal-transducing histidine kinase; E=4e-32 pir:E75617; sensor histidine kinase - Deinococcus radiodurans; E=6e-30 COG: DRA0205; COG0642 Sensory transduction histidine kinases; E=6e-31 PFAM: PF00672; HAMP domain; E=0.0036 PF00512; His Kinase A (phosphoacceptor) doma; E=7.2e-08 PF02518; Histidine kinase-, DNA gyrase B-, p; E=2e-35.
  
 
   0.791
RB2008
Signal-transducing histidine kinase; PMID: 9389475 best DB hits: BLAST: gb:AAB89763.1; (AE001000) signal-transducing histidine kinase; E=4e-29 embl:CAB62662.1; (AL133422) putative two-component sensor; E=9e-24 swissprot:Q9R6X3; PHYB_ANASP CYANOBACTERIAL PHYTOCHROME B -----; E=9e-22 COG: DR2419_2; COG0642 Sensory transduction histidine kinases; E=3e-21 PFAM: PF00785; PAC motif; E=7.7e-10 PF00512; His Kinase A (phosphoacceptor) doma; E=7.1e-09 PF02518; Histidine kinase-, DNA gyrase B-, p; E=3.1e-25.
  
 
   0.785
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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