Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
cph1Light-regulated histidine kinase 1; PMID: 10567266 best DB hits: BLAST: pir:C75276; sensory box sensor histidine kinase - Deinococcus; E=8e-45 swissprot:Q55168; PHY1_SYNY3 PHYTOCHROME-LIKE PROTEIN CPH1; E=1e-41 embl:CAB62662.1; (AL133422) putative two-component sensor; E=2e-41 COG: DR2419_2; COG0642 Sensory transduction histidine kinases; E=8e-46 PFAM: PF00512; His Kinase A (phosphoacceptor) doma; E=1e-12 PF02518; Histidine kinase-, DNA gyrase B-, p; E=3.5e-35. (582 aa)    
Predicted Functional Partners:
rcp1
Response regulator rcp1; PMID: 7699720 PMID: 9278513 best DB hits: BLAST: embl:CAB62661.1; (AL133422) hypothetical protein SCM1.03c; E=8e-33 pir:D75276; response regulator - Deinococcus radiodurans (strain R1); E=1e-31 swissprot:Q55169; RCP1_SYNY3 RESPONSE REGULATOR RCP1 -----; E=1e-25 COG: DR2420; COG0784 CheY-like receiver domains; E=1e-32 slr0115; COG0745 Response regulators consisting of a CheY-like; E=2e-09 sll0039; COG0784 CheY-like receiver domains; E=6e-09 PFAM: PF00072; Response regulator receiver doma; E=6.5e-19.
 
 
   0.952
RB2550
Probable response regulator; PMID: 9278513 best DB hits: BLAST: pir:B69158; sensory transduction regulatory protein -; E=8e-11 swissprot:Q55169; RCP1_SYNY3 RESPONSE REGULATOR RCP1 -----; E=1e-09 gb:AAB89775.1; (AE001001) response regulator [Archaeoglobus; E=2e-08 COG: MTH445; COG0784 CheY-like receiver domains; E=8e-12 PFAM: PF00072; Response regulator receiver doma; E=8.1e-11.
 
     0.774
RB11204
Hypothetical protein.
       0.773
RB7123
Probable response regulator; PMID: 10567266 best DB hits: BLAST: pir:D75276; response regulator - Deinococcus radiodurans (strain R1); E=4e-14 pir:A75522; response regulator - Deinococcus radiodurans (strain R1); E=8e-14 pir:D75617; response regulator - Deinococcus radiodurans (strain R1); E=4e-13 COG: DR2420; COG0784 CheY-like receiver domains; E=4e-15 sll0921; COG2197 Response regulators consisting of a CheY-like; E=1e-05 VC1349_3; COG0784 CheY-like receiver domains; E=3e-05 PFAM: PF00072; Response regulator receiver doma; E=5.6e-13.
 
     0.764
RB5780
Probable response regulator; PMID: 7699720 best DB hits: BLAST: pir:D75276; response regulator - Deinococcus radiodurans (strain R1); E=2e-09 embl:CAB62661.1; (AL133422) hypothetical protein SCM1.03c; E=4e-08 swissprot:Q55169; RCP1_SYNY3 RESPONSE REGULATOR RCP1 -----; E=4e-08 COG: DR2420; COG0784 CheY-like receiver domains; E=2e-10 VC0790; COG2197 Response regulators consisting of a CheY-like; E=0.002 citB; COG2197 Response regulators consisting of a CheY-like receiver; E=0.004 PFAM: PF00072; Response regulator receiver doma; E=2.1e-10.
 
     0.758
merA
Mercuric reductase; PMID: 2536669 PMID: 2067577 best DB hits: BLAST: pir:S75167; mercuric reductase - Synechocystis sp. (strain PCC 6803); E=1e-121 embl:CAA70224.1; (Y09024) mercuric reductase [Bacillus cereus]; E=9e-60 pir:T44505; merA protein [imported] - Clostridium butyricum -----; E=3e-59 COG: slr1849; COG1249 Dihydrolipoamide dehydrogenase/glutathione; E=1e-122 PFAM: PF00732; GMC oxidoreductases; E=0.074 PF02254; KTN NAD-binding domain; E=0.7 PF00899; ThiF family; E=0.22.
       0.741
RB1483
Probable sensor histidine kinase/response regulator; PMID: 10567266 best DB hits: BLAST: gb:AAF12583.1; AE001826_52 (AE001826) sensor histidine; E=4e-09 pir:D75429; sensory box sensor histidine kinase - Deinococcus; E=5e-09 pir:A69158; sensory transduction histidine kinase - Methanobacterium; E=6e-08 COG: DRB0029_2; COG0642 Sensory transduction histidine kinases; E=4e-10 PFAM: PF02518; Histidine kinase-, DNA gyrase B-, p; E=6.3e-13.
  
     0.731
RB6217
Putative response regulator; PMID: 10376842 best DB hits: BLAST: gb:AAD28578.1; AF121341_2 (AF121341) putative response regulator; E=7e-27 gb:AAA87378.1; (L42554) pleD gene product [Caulobacter; E=3e-21 pir:S74913; sensory transduction system regulatory protein slr1400 -; E=4e-21 COG: slr1400_1; COG0784 CheY-like receiver domains; E=4e-20 slr0115; COG0745 Response regulators consisting of a CheY-like; E=2e-19 VC0622_4; COG0784 CheY-like receiver domains; E=4e-19 PFAM: PF00072; Response regulator receiver doma; E=3.1e-37.
 
    0.722
RB5478
Putative two-component system response regulator; PMID: 7699720 best DB hits: BLAST: embl:CAB88489.1; (AL353816) putative two-component systen; E=1e-15 gb:AAB06615.1; (U53173) MviA [Salmonella typhimurium]; E=2e-14 gb:AAD30120.2; (AF135389) DNA binding response regulator RpaA; E=1e-13 COG: slr0115; COG0745 Response regulators consisting of a CheY-like; E=1e-13 XF1952_3; COG0784 CheY-like receiver domains; E=3e-13 Rv0981; COG0745 Response regulators consisting of a CheY-like; E=3e-12 PFAM: PF00072; Response regulator receiver doma; E=2.4e-27.
  
    0.706
RB5472
Probable two-component system response regulator; PMID: 1454550 best DB hits: BLAST: embl:CAB94653.1; (AL359215) putative two-component system; E=3e-12 pir:D72374; response regulator - Thermotoga maritima (strain MSB8); E=2e-11 embl:CAC04498.1; (AL391588) putative two-component system; E=5e-11 COG: TM0468; COG0784 CheY-like receiver domains; E=2e-12 BS_phoP; COG0745 Response regulators consisting of a CheY-like; E=3e-11 slr0322_3; COG0784 CheY-like receiver domains; E=3e-10 PFAM: PF00072; Response regulator receiver doma; E=9.1e-23.
  
    0.692
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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