STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RB11255Phosphatidate cytidylyltransferase; PMID: 2995359 PMID: 8557688 best DB hits: BLAST: gb:AAG56370.1; AE005365_4 (AE005365) putative phosphatidate; E=4e-24 swissprot:P76091; YNBB_ECOLI HYPOTHETICAL 33.1 KD PROTEIN IN; E=3e-22 pir:H82138; probable phosphatidate cytidylyltransferase VC1936; E=5e-22 COG: ynbB; COG0575 CDP-diglyceride synthetase; E=3e-23 PFAM: PF01148; Phosphatidate cytidylyltransfe; E=4.9e-16. (320 aa)    
Predicted Functional Partners:
pgsA-2
Probable phosphatidylglycerophosphate synthase; PMID: 8576035 PMID: 3031032 best DB hits: BLAST: prf:2206391A; phosphatidylglycerophosphate synthase [Rhodobacter; E=2e-04 gb:AAG44472.1; AF241784_1 (AF241784) CAPTase-iso [Homo sapiens]; E=7e-04 swissprot:Q50611; PGSA_MYCTU PUTATIVE; E=0.004 COG: Rv1822; COG0558 Phosphatidylglycerophosphate synthase; E=4e-04 PFAM: PF01066; CDP-alcohol phosphatidyltrans; E=0.00012; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
  
 
  0.989
pgsA
CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; PMID: 7750561 best DB hits: BLAST: ddbj:BAB06105.1; (AP001515) phosphatidylglycerophosphate synthase; E=7e-20 pir:I39950; pgsA protein - Bacillus subtilis ----- ddbj:; E=5e-16 swissprot:P46322; PGSA_BACSU; E=5e-15 COG: BH2386; COG0558 Phosphatidylglycerophosphate synthase; E=7e-21 PFAM: PF01066; CDP-alcohol phosphatidyltrans; E=1.1e-21; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
 
 
  0.962
cdsA
Phosphatidate cytidylyltransferase; PMID: 2995358 PMID: 2995359 best DB hits: BLAST: gb:AAK04086.1; (AE006236) unknown [Pasteurella multocida]; E=7e-53 pir:A83329; probable phosphatidate cytidylyltransferase PA2536; E=2e-51 pir:H82138; probable phosphatidate cytidylyltransferase VC1936; E=2e-32 COG: PA2536; COG0575 CDP-diglyceride synthetase; E=2e-52 PFAM: PF01148; Phosphatidate cytidylyltransf; E=5.5e-08.
  
  
 
0.928
cdS
Phosphatidate cytidylyltransferase; PMID: 2995358 PMID: 8557688 PMID: 9083091 best DB hits: BLAST: gb:AAB61972.1; (U60832) CDP-diglyceride synthetase [Haemophilus; E=2e-19 swissprot:P44937; CDSA_HAEIN PHOSPHATIDATE CYTIDYLYLTRANSFERASE; E=3e-19 gb:AAB61967.1; (U60831) CDP diglyceride synthetase [Haemophilus; E=3e-19 COG: HI0919; COG0575 CDP-diglyceride synthetase; E=2e-20 PFAM: PF01148; Phosphatidate cytidylyltransfe; E=5.6e-15.
  
  
 
0.928
pss
Probable CDP-diacylglycerol--serine O-phosphatidyltransferase; PMID: 2830250 best DB hits: BLAST: pir:F71678; CDPdiacylglycerol--serine O-phosphatidyltransferase (EC; E=1e-12 pir:G82804; phosphatidyltransferase XF0442 [imported] - Xylella; E=2e-12 pir:T47268; phosphatidylserine synthase [imported] - Helicobacter; E=3e-12 COG: RP242; COG1183 Phosphatidylserine synthase; E=1e-13 Rv2612c; COG0558 Phosphatidylglycerophosphate synthase; E=1e-05 AF2044; COG1183 Phosphatidylserine synthase; E=1e-05 PFAM: PF01066; CDP-alcohol phosphatidyltrans; E=1.1e-08; Belongs to the CDP-alcohol phosphatidy [...]
    
  0.903
RB4506
Probable phosphatidylcholine synthase; PMID: 20317087 best DB hits: BLAST: pir:D83165; conserved hypothetical protein PA3857 [imported] -; E=6e-19 pir:A70131; phosphatidyltransferase homolog - Lyme disease; E=2e-12 gb:AAF27310.1; AF155772_4 (AF155772) phosphatidylcholine synthase; E=4e-11 COG: BB0249; COG1183 Phosphatidylserine synthase; E=2e-13.
    
  0.903
RB11258
Best DB hits: BLAST: pir:C82165; conserved hypothetical protein VC1723 [imported] -; E=6e-12 swissprot:P71772; YE91_MYCTU HYPOTHETICAL 26.6 KDA PROTEIN RV1491C; E=8e-07 pir:B71448; hypothetical protein - Arabidopsis thaliana -----; E=1e-04 COG: VC1723; COG0398 Uncharacterized ACR; E=5e-13.
       0.773
dksA
Probable dnaK (dksA-like) supressor protein; PMID: 2180916 best DB hits: BLAST: pir:E81429; dksA-like protein Cj0125c [imported] - Campylobacter; E=1e-09 pir:D71366; probable dnaK suppressor - syphilis spirochete -----; E=2e-06 pir:T35472; hypothetical protein SC6C5.01 SC6C5.01 - Streptomyces; E=8e-06 COG: Cj0125c; COG1734 DnaK suppressor protein; E=2e-10 PFAM: PF01258; Prokaryotic dksA/traR C4-type zi; E=3.2e-10.
       0.773
der
Probable GTP-binding protein; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
  
     0.648
ffh
Signal recognition particle protein; PMID: 6357787 PMID: 1279430 best DB hits: BLAST: pir:F72236; signal recognition particle protein - Thermotoga; E=2e-87 ddbj:BAB06203.1; (AP001515) signal recognition particle [Bacillus; E=2e-85 gb:AAF69242.1; AF173880_5 (AF173880) signal recognition particle; E=3e-84 COG: TM1565; COG0541 Signal recognition particle GTPase; E=2e-88 PFAM: PF02881; SRP54-type protein, helical b; E=8.8e-21 PF02223; Thymidylate kinase; E=0.33 PF00485; Phosphoribulokinase / Uridine; E=0.03.
  
     0.594
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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