Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RB11258Best DB hits: BLAST: pir:C82165; conserved hypothetical protein VC1723 [imported] -; E=6e-12 swissprot:P71772; YE91_MYCTU HYPOTHETICAL 26.6 KDA PROTEIN RV1491C; E=8e-07 pir:B71448; hypothetical protein - Arabidopsis thaliana -----; E=1e-04 COG: VC1723; COG0398 Uncharacterized ACR; E=5e-13. (237 aa)    
Predicted Functional Partners:
pgsA-2
Probable phosphatidylglycerophosphate synthase; PMID: 8576035 PMID: 3031032 best DB hits: BLAST: prf:2206391A; phosphatidylglycerophosphate synthase [Rhodobacter; E=2e-04 gb:AAG44472.1; AF241784_1 (AF241784) CAPTase-iso [Homo sapiens]; E=7e-04 swissprot:Q50611; PGSA_MYCTU PUTATIVE; E=0.004 COG: Rv1822; COG0558 Phosphatidylglycerophosphate synthase; E=4e-04 PFAM: PF01066; CDP-alcohol phosphatidyltrans; E=0.00012; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
       0.778
RB11255
Phosphatidate cytidylyltransferase; PMID: 2995359 PMID: 8557688 best DB hits: BLAST: gb:AAG56370.1; AE005365_4 (AE005365) putative phosphatidate; E=4e-24 swissprot:P76091; YNBB_ECOLI HYPOTHETICAL 33.1 KD PROTEIN IN; E=3e-22 pir:H82138; probable phosphatidate cytidylyltransferase VC1936; E=5e-22 COG: ynbB; COG0575 CDP-diglyceride synthetase; E=3e-23 PFAM: PF01148; Phosphatidate cytidylyltransfe; E=4.9e-16.
       0.773
dksA
Probable dnaK (dksA-like) supressor protein; PMID: 2180916 best DB hits: BLAST: pir:E81429; dksA-like protein Cj0125c [imported] - Campylobacter; E=1e-09 pir:D71366; probable dnaK suppressor - syphilis spirochete -----; E=2e-06 pir:T35472; hypothetical protein SC6C5.01 SC6C5.01 - Streptomyces; E=8e-06 COG: Cj0125c; COG1734 DnaK suppressor protein; E=2e-10 PFAM: PF01258; Prokaryotic dksA/traR C4-type zi; E=3.2e-10.
       0.773
merA
Mercuric reductase; PMID: 2536669 PMID: 2067577 best DB hits: BLAST: pir:S75167; mercuric reductase - Synechocystis sp. (strain PCC 6803); E=1e-121 embl:CAA70224.1; (Y09024) mercuric reductase [Bacillus cereus]; E=9e-60 pir:T44505; merA protein [imported] - Clostridium butyricum -----; E=3e-59 COG: slr1849; COG1249 Dihydrolipoamide dehydrogenase/glutathione; E=1e-122 PFAM: PF00732; GMC oxidoreductases; E=0.074 PF02254; KTN NAD-binding domain; E=0.7 PF00899; ThiF family; E=0.22.
 
     0.684
RB2206
Conserved hypothetical protein; PMID: 8905231 best DB hits: BLAST: pir:S76621; hypothetical protein - Synechocystis sp. (strain PCC; E=9e-23 ddbj:BAA84086.1; (AB032065) hypothetical protein [Streptomyces; E=6e-21 embl:CAB61873.1; (AL133252) hypothetical protein SCE46.22; E=6e-21 COG: slr0092; COG0463 Glycosyltransferases involved in cell wall; E=8e-24 PAB1314; COG1215 Glycosyltransferases, probably involved in cell; E=2e-07 Rv2957; COG0463 Glycosyltransferases involved in cell wall; E=7e-07 PFAM: PF00535; Glycosyl transferase; E=2.6e-21.
 
     0.599
RB8932
Conserved hypothetical protein; Best DB hits: BLAST: ddbj:BAA84086.1; (AB032065) hypothetical protein [Streptomyces; E=3e-15 embl:CAB61872.1; (AL133252) hypothetical protein SCE46.21; E=7e-14 gb:AAC15821.1; (U44977) unknown [Prochlorococcus marinus]; E=7e-13 COG: sll1095; COG3222 Uncharacterized BCR; E=5e-08.
 
     0.547
RB11262
Best DB hits: BLAST: pir:D83268; conserved hypothetical protein PA3023 [imported] -; E=6e-20 swissprot:P76407; YEGS_ECOLI HYPOTHETICAL 32.0 KDA PROTEIN IN; E=9e-14 gb:AAG57146.1; AE005435_4 (AE005435) orf, hypothetical protein; E=3e-13 COG: PA3023; COG1597 Uncharacterized ACR; E=6e-21 PFAM: PF00781; Diacylglycerol kinase catalyti; E=0.0004.
       0.526
RB6747
Conserved hypothetical protein-putative Fe-S oxidoreductases; PMID: 8905231 best DB hits: BLAST: pir:S76979; hypothetical protein - Synechocystis sp. (strain PCC; E=3e-56 embl:CAC24148.1; (AL512973) Hypothetical protein [Sulfolobus; E=5e-05 pir:C83581; heme d1 biosynthesis protein NirJ PA0511 [imported] -; E=0.016 COG: slr0304; COG0535 Predicted Fe-S oxidoreductases; E=3e-57.
 
     0.427
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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