STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RB11262Best DB hits: BLAST: pir:D83268; conserved hypothetical protein PA3023 [imported] -; E=6e-20 swissprot:P76407; YEGS_ECOLI HYPOTHETICAL 32.0 KDA PROTEIN IN; E=9e-14 gb:AAG57146.1; AE005435_4 (AE005435) orf, hypothetical protein; E=3e-13 COG: PA3023; COG1597 Uncharacterized ACR; E=6e-21 PFAM: PF00781; Diacylglycerol kinase catalyti; E=0.0004. (331 aa)    
Predicted Functional Partners:
RB11255
Phosphatidate cytidylyltransferase; PMID: 2995359 PMID: 8557688 best DB hits: BLAST: gb:AAG56370.1; AE005365_4 (AE005365) putative phosphatidate; E=4e-24 swissprot:P76091; YNBB_ECOLI HYPOTHETICAL 33.1 KD PROTEIN IN; E=3e-22 pir:H82138; probable phosphatidate cytidylyltransferase VC1936; E=5e-22 COG: ynbB; COG0575 CDP-diglyceride synthetase; E=3e-23 PFAM: PF01148; Phosphatidate cytidylyltransfe; E=4.9e-16.
 
     0.586
pgsA-2
Probable phosphatidylglycerophosphate synthase; PMID: 8576035 PMID: 3031032 best DB hits: BLAST: prf:2206391A; phosphatidylglycerophosphate synthase [Rhodobacter; E=2e-04 gb:AAG44472.1; AF241784_1 (AF241784) CAPTase-iso [Homo sapiens]; E=7e-04 swissprot:Q50611; PGSA_MYCTU PUTATIVE; E=0.004 COG: Rv1822; COG0558 Phosphatidylglycerophosphate synthase; E=4e-04 PFAM: PF01066; CDP-alcohol phosphatidyltrans; E=0.00012; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
  
  
 0.565
eno
Enolase (2-phosphoglycerate dehydratase); Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
   
    0.539
dksA
Probable dnaK (dksA-like) supressor protein; PMID: 2180916 best DB hits: BLAST: pir:E81429; dksA-like protein Cj0125c [imported] - Campylobacter; E=1e-09 pir:D71366; probable dnaK suppressor - syphilis spirochete -----; E=2e-06 pir:T35472; hypothetical protein SC6C5.01 SC6C5.01 - Streptomyces; E=8e-06 COG: Cj0125c; COG1734 DnaK suppressor protein; E=2e-10 PFAM: PF01258; Prokaryotic dksA/traR C4-type zi; E=3.2e-10.
  
    0.536
RB11258
Best DB hits: BLAST: pir:C82165; conserved hypothetical protein VC1723 [imported] -; E=6e-12 swissprot:P71772; YE91_MYCTU HYPOTHETICAL 26.6 KDA PROTEIN RV1491C; E=8e-07 pir:B71448; hypothetical protein - Arabidopsis thaliana -----; E=1e-04 COG: VC1723; COG0398 Uncharacterized ACR; E=5e-13.
       0.528
cpdA
3,5-cyclic-nucleotide phosphodiesterase cpdA homolog; Best DB hits: BLAST: pir:C69097; 3',5'-cyclic-nucleotide phosphodiesterase (EC 3.1.4.17); E=8e-16 pir:A70360; 3',5'-cyclic-nucleotide phosphodiesterase (EC 3.1.4.17); E=7e-13 pir:F69104; 3',5'-cyclic-nucleotide phosphodiesterase (EC 3.1.4.17); E=2e-11 COG: MTH1722; COG1409 Predicted phosphohydrolases; E=8e-17 APE0113; COG0420 DNA repair exonuclease; E=0.001 HI0399; COG1409 Predicted phosphohydrolases; E=0.001 PFAM: PF02549; DNA repair exonuclease; E=4.2e-06.
       0.517
RB6566
Similar to protein BmrU; PMID: 11214968 best DB hits: BLAST: swissprot:P39074; BMRU_BACSU BMRU PROTEIN ----- pir: F69595; E=0.057 pir:H70861; hypothetical protein Rv2252 - Mycobacterium tuberculosis; E=0.26 pir:H69995; hypothetical protein ytlR - Bacillus subtilis -----; E=0.35.
  
     0.480
RB386
Saframycin Mx1 synthetase B; PMID: 8936303 best DB hits: BLAST: pir:T18551; saframycin Mx1 synthetase B - Myxococcus xanthus -----; E=1e-112 pir:T34918; polyketide synthase - Streptomyces coelicolor -----; E=1e-102 pir:H83343; probable non-ribosomal peptide synthetase PA2424; E=1e-101 COG: PA2424_1; COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid; E=1e-102 Rv1529; COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases; E=7e-83 Ta1189; COG0156 7-keto-8-aminopelargonate synthetase and related; E=6e-62 PFAM: PF00501; AMP-binding enzyme; E=2.2e-08 PF00550; Phosphopantetheine attac [...]
   
 
 0.443
RB9228
Hypothetical protein.
    
  0.440
gltB
Glutamate synthase [NADPH] large chain; PMID: 2643092 PMID: 3326786 best DB hits: BLAST: swissprot:Q06434; GLSF_ANTSP FERREDOXIN-DEPENDENT GLUTAMATE SYNTHASE; E=0.0 swissprot:P23225; GLSF_MAIZE FERREDOXIN-DEPENDENT GLUTAMATE; E=0.0 swissprot:Q03460; GLSN_MEDSA GLUTAMATE SYNTHASE [NADH], CHLOROPLAST; E=0.0 COG: sll1502_2; COG0069 Glutamate synthetase domain 2; E=0.0 sll1502_1; COG0067 Glutamate synthetase domain 1; E=1e-118 PFAM: PF01645; Conserved region in glutamate; E=5.5e-235 PF01493; Domain of unknown function DU; E=4.2e-95.
  
  
 0.425
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.