STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RB11331Probable glutathione-regulated potassium-efflux system protein KefB; PMID: 2046548 PMID: 8412700 best DB hits: BLAST: pir:T35377; probable membrane protein - Streptomyces coelicolor; E=4e-08 pir:S76244; hypothetical protein - Synechocystis sp. (strain PCC; E=6e-06 pir:S76018; hypothetical protein - Synechocystis sp. (strain PCC; E=3e-04 COG: sll0261; COG1226 Kef-type K+ transport systems, predicted; E=6e-07 DR2336; COG1226 Kef-type K+ transport systems, predicted NAD-binding; E=4e-04 MJ0138.1; COG1226 Kef-type K+ transport systems, predicted; E=7e-04 PFAM: PF01408; Oxidoreductase famil [...] (809 aa)    
Predicted Functional Partners:
iuvY
Probable transcriptional activator protein ilvY; PMID: 10588699 PMID: 9556617 best DB hits: BLAST: swissprot:P05827; ILVY_ECOLI TRANSCRIPTIONAL ACTIVATOR PROTEIN; E=1e-05 pir:S30671; ilvC activator - Escherichia coli; E=1e-05 gb:AAG58968.1; AE005608_9 (AE005608) positive regulator for ilvC; E=1e-05 COG: ilvY; COG0583 Transcriptional regulator; E=9e-07 PFAM: PF00126; Bacterial regulatory helix-turn-heli; E=6.1e-15; Belongs to the LysR transcriptional regulatory family.
 
    0.812
RB11329
Hypothetical protein.
       0.773
RB11334
Serine/threonine-protein kinase; PMID: 3291115 best DB hits: BLAST: gb:AAF73695.1; (AE002226) serinethreonine-protein kinase; E=1e-35 pir:G71532; probable threoninetyrosine-specific protein kinase (EC; E=8e-34 pir:C72120; st protein kinase - Chlamydophila pneumoniae (strain; E=5e-33 COG: CT301_1; COG0515 Serine/threonine protein kinases; E=8e-35 PFAM: PF00069; Protein kinase domain; E=2.6e-37 PF00400; WD domain, G-beta repeat; E=0.013 PF00515; TPR Domain; E=0.0067.
       0.613
RB11323
Hypothetical protein.
       0.506
RB11325
Hypothetical protein.
       0.506
nhaP
Putative Na(+)/H(+) exchanger ycgO; PMID: 9507001 PMID: 9278382 PMID: 9537504 best DB hits: BLAST: pir:C82043; conserved hypothetical protein VC2703 [imported] -; E=2e-76 swissprot:P76007; YCGO_ECOLI PUTATIVE NA(+)H(+) EXCHANGER YCGO; E=5e-74 ddbj:BAB07757.1; (AP001520) Na+H+ antiporter [Bacillus; E=2e-71 COG: VC2703_1; COG0025 NhaP-type Na+/H+ and K+/H+ antiporters; E=1e-64 VC2703_2; COG3263 Uncharacterized BCR; E=1e-04 sll0556_1; COG0025 NhaP-type Na+/H+ and K+/H+ antiporters; E=1e-04 PFAM: PF00999; Sodium/hydrogen exchanger fami; E=2.8e-60 PF02080; Potassium channel; E=5e-05.
 
   
 0.430
afsR-g
Probable regulatory protein afsR; PMID: 10517581 best DB hits: BLAST: ddbj:BAA83790.1; (AB025225) AfsR-g [Streptomyces griseus]; E=2e-05 embl:CAB72409.1; (AL138978) putative AfsR-like regulator; E=9e-04 swissprot:P25941; AFSR_STRCO REGULATORY PROTEIN AFSR -----; E=0.003 PFAM: PF00293; MutT-like domain; E=2.9e-06 PF00515; TPR Domain; E=0.28.
       0.429
RB11320
Hypothetical protein.
       0.428
RB11337
Probable transposase; PMID: 8041625 best DB hits: BLAST: pir:S35005; probable transposase - Acetobacter xylinus insertion; E=9e-21 pir:S35004; probable transposase - Acetobacter xylinus insertion; E=4e-20 gb:AAD47597.1; AF144038_1 (AF144038) putative transposase; E=2e-18 COG: sll1716; COG3293 Predicted transposase; E=2e-13 PFAM: PF01511; Transposase; E=1.2e-09 PF01675; Transposase; E=2.5e-05.
       0.419
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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