Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RB11510PMID: 1435734 best DB hits: BLAST: ddbj:BAB05504.1; (AP001513) chaperonin involved in protein; E=5e-21 swissprot:P37584; CSAA_BACSU CSAA PROTEIN ----- pir: E69607; E=1e-20 pir:A83243; CsaA protein PA3221 [imported] - Pseudomonas aeruginosa; E=1e-20 COG: BH1785; COG0073 EMAP domain; E=5e-22 PFAM: PF01588; Putative tRNA binding domain; E=2.3e-13. (266 aa)    
Predicted Functional Partners:
pheS
phenylalanyl-tRNA synthetase alpha chain; PMID: 6317865 best DB hits: BLAST: embl:CAA23564.1; (V00291) phenylalanyl-tRNA synthetase; E=6e-76 gb:AAA51469.1; (K02844) phenylalanyl-tRNA synthetase; E=6e-76 swissprot:P08312; SYFA_ECOLI PHENYLALANYL-TRNA SYNTHETASE ALPHA; E=3e-75 COG: pheS; COG0016 Phenylalanyl-tRNA synthetase alpha subunit; E=3e-76 PFAM: PF02912; Aminoacyl tRNA synthetase class; E=3.9e-08 PF01409; tRNA synthetases class II (F); E=9.4e-92; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
  
 
 0.909
RB11509
Hypothetical protein.
       0.791
RB11506
Probable 4-oxalocrotonate tautomerase; PMID: 1732207 PMID: 8547259 best DB hits: BLAST: swissprot:P45418; YKDK_ERWCH HYPOTHETICAL 8.1 KD PROTEIN IN KDGK; E=3e-06 pir:H81078; 4-oxalocrotonate tautomerase, probable NMB1474; E=8e-06 gb:AAG42543.1; (AY013584) putative isomerase [Sinorhizobium; E=2e-04 COG: NMB1474; COG1942 Uncharacterized protein, 4-oxalocrotonate; E=8e-07 PFAM: PF01361; Tautomerase enzyme; E=1.2e-06.
       0.732
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
  
 0.530
RB11505
Conserved hypothetical protein; PMID: 8905231 best DB hits: BLAST: pir:S76701; hypothetical protein - Synechocystis sp. (strain PCC; E=1e-11 pir:T04873; hypothetical protein F28A21.220 - Arabidopsis thaliana; E=5e-10 gb:AAD34060.1; AF151823_1 (AF151823) CGI-65 protein [Homo sapiens]; E=1e-07 COG: sll0096; COG0702 Predicted nucleoside-diphosphate-sugar epimerases; E=1e-12.
       0.517
guaA-2
GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
  
 0.517
RB11512
Conserved hypothetical protein-putative phenazine biosynthesis protein PhzF; PMID: 8586283 best DB hits: BLAST: ddbj:BAB04002.1; (AP001508) BH0283~unknown conserved protein; E=5e-62 pir:E83199; conserved hypothetical protein PA3578 [imported] -; E=1e-57 pir:A83301; hypothetical protein PA2770 [imported] - Pseudomonas; E=3e-56 COG: BH0283; COG0384 Predicted epimerase, PhzC/PhzF homolog; E=5e-63 PFAM: PF02567; Phenazine biosynthesis-like protein; E=7.7e-27.
       0.514
gltB
Glutamate synthase [NADPH] large chain; PMID: 2643092 PMID: 3326786 best DB hits: BLAST: swissprot:Q06434; GLSF_ANTSP FERREDOXIN-DEPENDENT GLUTAMATE SYNTHASE; E=0.0 swissprot:P23225; GLSF_MAIZE FERREDOXIN-DEPENDENT GLUTAMATE; E=0.0 swissprot:Q03460; GLSN_MEDSA GLUTAMATE SYNTHASE [NADH], CHLOROPLAST; E=0.0 COG: sll1502_2; COG0069 Glutamate synthetase domain 2; E=0.0 sll1502_1; COG0067 Glutamate synthetase domain 1; E=1e-118 PFAM: PF01645; Conserved region in glutamate; E=5.5e-235 PF01493; Domain of unknown function DU; E=4.2e-95.
     
 0.475
dnaQ
Best DB hits: BLAST: swissprot:P13267; DPO3_BACSU DNA POLYMERASE III, ALPHA CHAIN; E=8e-09 pir:JH0232; DNA-directed DNA polymerase (EC 2.7.7.7) III alpha chain; E=8e-09 gb:AAA22666.1; (M22996) polymerase III [Bacillus subtilis]; E=9e-09 COG: BS_polC; COG2176 DNA polymerase III alpha subunit, the Gram-positive; E=8e-10 Rv2191_1; COG0847 DNA polymerase III epsilon subunit (3'-5'; E=2e-09 TM0576; COG2176 DNA polymerase III alpha subunit, the Gram-positive; E=6e-08 PFAM: PF00929; Exonuclease; E=1.2e-18 PF00533; BRCA1 C Terminus (BRCT) domain; E=2.4e-09.
  
  
 0.424
purL
Phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...]
  
  
 0.421
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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