STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
drgadrgA protein; PMID: 9654132 PMID: 8905231 best DB hits: BLAST: pir:S75047; drgA protein - Synechocystis sp. (strain PCC 6803); E=3e-60 swissprot:Q55233; DRGA_SYNY3 DRGA PROTEIN ----- gb: AAA91952.1; E=7e-56 pir:E82996; probable nitroreductase PA5190 [imported] - Pseudomonas; E=7e-41 COG: slr1719; COG0778 Nitroreductase; E=3e-61 PFAM: PF00881; Nitroreductase family; E=1.3e-44. (201 aa)    
Predicted Functional Partners:
natB-2
Best DB hits: BLAST: pir:A75459; sodium extrusion protein NatB - Deinococcus radiodurans; E=2e-15 swissprot:P46904; NATB_BACSU PROTEIN NATB ----- pir: B69666; E=1e-10 ddbj:BAA22237.1; (AB000617) NatB [Bacillus subtilis]; E=5e-05 COG: DR0926; COG1668 ATP-dependent Na+ efflux pump membrane component; E=1e-16 BS_ydiL; COG1266 Predicted metal-dependent membrane protease; E=1e-04 PFAM: PF02517; CAAX amino terminal protease family; E=1.1e-19.
  
  
 0.650
RB11564
Probable permease component of an ABC-transporter; PMID: 9384377 best DB hits: BLAST: pir:H69803; ABC transporter (ATP-binding protein) homolog yfiM -; E=1e-05 ddbj:BAA83956.1; (AB024563) YFIM [Bacillus halodurans]; E=0.83 ddbj:BAB04774.1; (AP001510) BH1055~unknown conserved protein; E=0.83 COG: BS_yfiM; COG0842 Permease component of an ABC-transporter; E=1e-06.
  
  
 0.606
RB11929
Probable membrane protein; PMID: 9371463 PMID: 1924314 best DB hits: BLAST: pir:B69012; probable membrane protein MTH1092 - Methanobacterium; E=7e-22 gb:AAB89369.1; (AE000972) daunorubicin resistance membrane; E=5e-14 pir:D75108; daunorubicin resistance membrane protein (drrb) PAB1924; E=9e-14 COG: MTH1092; COG0842 Permease component of an ABC-transporter; E=6e-23.
  
  
 0.606
RB11548
Hypothetical protein-signal peptide and transmembrane prediction.
       0.605
RB11551
Hypothetical protein.
       0.574
RB3774
Conserved hypothetical protein; PMID: 10484179 best DB hits: BLAST: swissprot:P54540; YQJC_BACSU HYPOTHETICAL 15.7 KD PROTEIN IN; E=1e-15 ddbj:BAB05187.1; (AP001512) BH1468~unknown conserved protein; E=4e-15 pir:A71452; glyoxalase I related protein PH0272 [similarity] -; E=2e-13 COG: BS_yqjC; COG0346 Lactoylglutathione lyase; E=9e-17 PFAM: PF00903; Glyoxalase/Bleomycin resistance pr; E=3.7e-09.
  
  
 0.551
RB3840
Similar to dioxygenase superfamily; PMID: 9168618 best DB hits: PFAM: PF00903; Glyoxalase/Bleomycin resistance pr; E=5.3e-10.
  
  
 0.551
ribA
Riboflavin biosynthesis protein RibA; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. In the N-terminal section; belongs to the DHBP synthase family.
  
 
 0.510
RB386
Saframycin Mx1 synthetase B; PMID: 8936303 best DB hits: BLAST: pir:T18551; saframycin Mx1 synthetase B - Myxococcus xanthus -----; E=1e-112 pir:T34918; polyketide synthase - Streptomyces coelicolor -----; E=1e-102 pir:H83343; probable non-ribosomal peptide synthetase PA2424; E=1e-101 COG: PA2424_1; COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid; E=1e-102 Rv1529; COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases; E=7e-83 Ta1189; COG0156 7-keto-8-aminopelargonate synthetase and related; E=6e-62 PFAM: PF00501; AMP-binding enzyme; E=2.2e-08 PF00550; Phosphopantetheine attac [...]
   
 
 0.505
RB6500
Mycocerosate synthase; PMID: 3880746 best DB hits: BLAST: pir:S72705; mycocerosate synthase (EC 2.3.1.111) - Mycobacterium; E=0.0 pir:H70819; probable polyketide synthase - Mycobacterium tuberculosis; E=0.0 gb:AAF62883.1; AF217189_6 (AF217189) epoD [Sorangium cellulosum]; E=1e-180 COG: PA2402_3; COG1020 Non-ribosomal peptide synthetase modules and related; E=4e-99 BS_ppsD_3; COG1020 Non-ribosomal peptide synthetase modules and; E=4e-92 PA2424_2; COG1020 Non-ribosomal peptide synthetase modules and related; E=1e-91 PFAM: PF00108; Thiolase, N-terminal domain; E=2.7e-06 PF00109; Beta-keto [...]
  
 
 0.472
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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