STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
degTPleiotropic regulatory protein; PMID: 2104607 best DB hits: BLAST: swissprot:P15263; DEGT_BACST PLEIOTROPIC REGULATORY PROTEIN; E=2e-80 ddbj:BAA31964.1; (D64132) A porR mutant of Pophyromonas; E=3e-68 pir:D69025; pleiotropic regulatory protein DegT - Methanobacterium; E=2e-67 COG: MTH1188; COG0399 Predicted pyridoxal phosphate-dependent enzyme; E=2e-68 PFAM: PF01041; DegT/DnrJ/EryC1/StrS family; E=1.2e-146; Belongs to the DegT/DnrJ/EryC1 family. (417 aa)    
Predicted Functional Partners:
amsG
UDP-galactose-lipid carrier transferase; PMID: 7596293 best DB hits: BLAST: swissprot:Q57491; Y872_HAEIN HYPOTHETICAL SUGAR TRANSFERASE HI0872; E=3e-56 swissprot:Q46628; AMSG_ERWAM UDP-GALACTOSE-LIPID CARRIER; E=5e-56 pir:S61891; undecaprenyl-phosphate galactosephosphotransferase (EC; E=5e-56 COG: HI0872; COG2148 Sugar transferases involved in lipopolysaccharide; E=2e-57 PFAM: PF00895; ATP synthase protein 8; E=0.37 PF02397; Bacterial sugar transferase; E=3.6e-89.
  
 0.954
RB4937
Conserved hypothetical protein-putative NADH-dependent dehydrogenase; PMID: 8905231 best DB hits: BLAST: pir:S76068; hypothetical protein - Synechocystis sp. (strain PCC; E=3e-23 pir:H69216; 3-chlorobenzoate-3,4-dioxygenase dyhydrogenase related; E=3e-22 pir:E75096; NADH-dependent dehydrogenase homolog. PAB0775 -; E=9e-16 COG: slr0338; COG0673 Predicted dehydrogenases and related proteins; E=3e-24 PFAM: PF02871; NAD/NADP octopine/nopaline deh; E=0.21 PF01113; Dihydrodipicolinate reductase; E=0.045 PF00547; Urease, gamma subunit; E=0.84.
 
    0.898
RB2515
Probable UDP-glucose/GDP-mannose dehydrogenase; PMID: 10984043 best DB hits: BLAST: pir:A83252; probable UDP-glucoseGDP-mannose dehydrogenase WbpA; E=1e-124 pir:H72358; lipopolysaccharide biosynthesis protein - Thermotoga; E=4e-93 pir:F71153; probable Vi polysaccharide biosynthesis protein -; E=8e-85 COG: PA3159; COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase; E=1e-125 VNG0046G; COG1004 Predicted UDP-glucose 6-dehydrogenase; E=9e-24 PFAM: PF00984; UDP-glucose/GDP-mannose dehydro; E=3.9e-131.
 
  
 0.871
exbD-2
Probable biopolymer transport ExbD protein; PMID: 2670903 PMID: 10517598 best DB hits: BLAST: gb:AAC78852.1; (AF087669) ExbD [Bordetella bronchiseptica]; E=1e-06 pir:T44783; exbD protein [imported] - Bordetella pertussis -----; E=3e-06 pir:A71687; tolR protein (tolR) RP310 - Rickettsia prowazekii; E=3e-06 COG: RP310; COG0848 Biopolymer transport protein; E=4e-07 PFAM: PF02472; Biopolymer transport protein ExbD/To; E=4.1e-10.
       0.773
exbB
Probable biopolymer transport ExbB-related protein; PMID: 8437515 best DB hits: BLAST: pir:D82726; conserved hypothetical protein XF1079 [imported] -; E=8e-21 pir:G83274; probable tolQ-type transport protein PA2983 [imported] -; E=4e-19 embl:CAB50918.1; (AJ243354) hypothetical protein [Pseudomonas; E=8e-16 COG: XF1079; COG0811 Biopolymer transport proteins; E=8e-22 PFAM: PF01618; MotA/TolQ/ExbB proton channel famil; E=3.1e-21.
       0.773
RB1168
Hypothetical protein-transmembrane prediction; Best DB hits: BLAST: pir:B81428; probable periplasmic protein Cj0114 [imported] -; E=0.62.
       0.773
RB1161
Best DB hits: BLAST: pir:T35404; probable squalene-hopene cyclase - Streptomyces; E=0.035 ddbj:BAB09653.1; (AB016881) gene_id:MXC17.10~unknown protein; E=0.073 gb:AAF80384.1; AF159949_1 (AF159949) cycloartenol synthase; E=0.79.
       0.727
RB6199
Dehydrogenase homolog; PMID: 8821935 best DB hits: BLAST: pir:S70672; dehydrogenase homolog - Bordetella pertussis -----; E=5e-50 gb:AAD45293.1; AF156256_1 (AF156256) putative dehydrogenase; E=3e-44 embl:CAC24056.1; (AL512981) Hypothetical-conserved [Sulfolobus; E=3e-43 COG: TM0585; COG0673 Predicted dehydrogenases and related proteins; E=2e-40 PFAM: PF01958; Domain of unknown function DUF; E=0.00025 PF01408; Oxidoreductase family, NAD-bin; E=2.1e-40 PF02894; Oxidoreductase family, C-termi; E=1.4e-16.
 
    0.720
wecB
PMID: 8226648 best DB hits: BLAST: pir:A82264; UDP-N-acetylglucosamine 2-epimerase VC0917 [imported] -; E=1e-106 pir:T44828; probable UDP-N-acetylglucosamine 2-epimerase (EC; E=1e-101 swissprot:P27828; WECB_ECOLI UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE; E=1e-101 COG: VC0917; COG0381 UDP-N-acetylglucosamine 2-epimerase; E=1e-107 PFAM: PF02350; UDP-N-acetylglucosamine 2-epimera; E=1.7e-162; Belongs to the UDP-N-acetylglucosamine 2-epimerase family.
  
  
 0.699
rfbB
dTDP-glucose-4,6-dehydratase; PMID: 8022265 best DB hits: BLAST: gb:AAG35060.1; AF314183_2 (AF314183) dTDP-glucose-4,6-dehydratase; E=1e-110 gb:AAF33465.1; (AF233324) 89% identity with E. coli; E=1e-107 swissprot:P55294; RFBB_NEIMB DTDP-GLUCOSE 4,6-DEHYDRATASE -----; E=1e-106 COG: NMB0063; COG1088 dTDP-D-glucose 4,6-dehydratase; E=1e-107 PFAM: PF01073; 3-beta hydroxysteroid dehydro; E=0.53 PF00106; short chain dehydrogenase; E=0.073 PF01370; NAD dependent epimerase/dehyd; E=6e-141; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.
  
  
 0.641
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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