STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RB11712Swi/snf family helicase_2; PMID: 7908117 best DB hits: BLAST: pir:C72027; swisnf family helicase_2 - Chlamydophila pneumoniae; E=1e-50 gb:AAC71234.1; (U39681) ATP-dependent RNA helicase, putative; E=4e-50 ddbj:BAA99057.1; (AP002548) SWISNF family helicase_2; E=5e-50 COG: CPn0849; COG0553 Superfamily II DNA/RNA helicases, SNF2 family; E=1e-51 PFAM: PF01102; Glycophorin A; E=0.41 PF00176; SNF2 and others N-terminal doma; E=6.4e-34 PF00271; Helicase conserved C-terminal d; E=1e-17. (647 aa)    
Predicted Functional Partners:
rpoA-2
PMID: 9835038 best DB hits: BLAST: swissprot:O50634; RPOA_BACHD DNA-DIRECTED RNA POLYMERASE ALPHA; E=2e-09 swissprot:Q9Z3E7; RPOA_XANCP DNA-DIRECTED RNA POLYMERASE ALPHA; E=4e-09 gb:AAD00325.2; (U79735) RNA polymerase ALPHA subunit [Xanthomonas; E=4e-09 COG: BH0162; COG0202 DNA-directed RNA polymerase alpha subunit/40 kD; E=2e-10 PFAM: PF00515; TPR Domain; E=0.87 PF01000; Bacterial RNA polymerase, alpha; E=6.5e-12.
  
 0.968
rpoZ
Hypothetical protein; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
    
 0.903
rpoB
DNA-directed RNA polymerase beta chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 0.899
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.817
RB11708
Conserved hypothetical protein; PMID: 10360571 best DB hits: BLAST: pir:C72318; hypothetical protein - Thermotoga maritima (strain MSB8); E=7e-04.
       0.806
RB11703
Hypothetical protein.
       0.610
RB11704
Hypothetical protein.
       0.610
RB11706
Periplasmic serine proteinase Do; PMID: 3057437 best DB hits: BLAST: pir:F72359; periplasmic serine proteinase Do (EC 3.4.21.-) -; E=9e-41 pir:F81329; serine proteinase (proteinase DO) (EC 3.4.21.-) Cj1228c; E=2e-40 embl:CAA57948.1; (X82628) serine protease [Campylobacter jejuni]; E=2e-40 COG: TM0571; COG0265 Trypsin-like serine proteases, typically; E=8e-42 CT823; COG0265 Trypsin-like serine proteases, typically periplasmic,; E=2e-40 PA0766; COG0265 Trypsin-like serine proteases, typically; E=5e-40 PFAM: PF00089; Trypsin; E=3.8e-20 PF00595; PDZ domain (Also known as DHR or GLG; E=4.9e-06.
       0.610
RB11707
Hypothetical protein.
       0.610
rpoC
DNA-directed RNA polymerase beta chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
  0.585
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.