Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RB11907Conserved hypothetical protein; Best DB hits: BLAST: gb:AAF00629.1; AC009540_6 (AC009540) unknown protein [Arabidopsis; E=1e-04 gb:AAF61443.1; AF139187_1 (AF139187) root border cell-specific; E=5e-04 pir:E83098; hypothetical protein PA4388 [imported] - Pseudomonas; E=0.020 COG: PA4388; COG0748 Uncharacterized BCR; E=0.002. (158 aa)    
Predicted Functional Partners:
hemH
Probable ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
     
 0.906
RB10088
Conserved hypothetical protein; Best DB hits: BLAST: ddbj:BAB07544.1; (AP001520) BH3825~unknown conserved protein; E=7e-27 swissprot:P39645; YWFI_BACSU HYPOTHETICAL 29.5 KD PROTEIN IN; E=5e-24 gb:AAG20186.1; (AE005095) Vng2021c [Halobacterium sp. NRC-1]; E=7e-24 COG: BH3825; COG3253 Uncharacterized ACR; E=7e-28.
     
  0.900
bfr
Bacterioferritin; Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex; Belongs to the bacterioferritin family.
     
  0.900
cyoE
Protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
     
  0.900
RB1753
Conserved hypothetical protein; PMID: 10960085 best DB hits: BLAST: embl:CAB95035.1; (AJ272497) orf4 [Bacillus anthracis]; E=9e-12 pir:B83036; probable bacterioferritin PA4880 [imported] -; E=0.005 pir:G82332; bacterioferritin VC0365 [imported] - Vibrio cholerae; E=0.019 COG: PA4880; COG2193 Bacterioferritin (cytochrome b1); E=5e-04.
     
  0.900
RB11906
Hypothetical acetyltransferase; PMID: 11078650 best DB hits: BLAST: gb:AAF64052.1; AF242367_1 (AF242367) hypothetical; E=1e-10 embl:CAA63806.1; (X93605) hypothetical protein [Zymomonas; E=4e-08 pir:D72219; conserved hypothetical protein - Thermotoga maritima; E=5e-07 COG: TM1720; COG0454 Histone acetyltransferase HPA2 and related; E=4e-08 PFAM: PF00583; Acetyltransferase (GNAT) family; E=4.9e-11.
       0.778
RB11909
Hypothetical protein-transmembrane prediction; Best DB hits: PFAM: PF01330; RuvA N terminal domain; E=0.83.
       0.773
moxR
Methanol dehydrogenase regulatory protein; PMID: 1657871 PMID: 10086841 best DB hits: BLAST: pir:H72289; hypothetical protein TM1132 - Thermotoga maritima; E=5e-70 ddbj:BAB04323.1; (AP001509) methanol dehydrogenase regulatory; E=4e-69 pir:S75782; methanol dehydrogenase regulatory protein -; E=3e-67 COG: TM1132; COG0714 MoxR-like ATPases; E=5e-71 PFAM: PF00004; ATPase family associated with va; E=0.00074 PF01506; Hepatitis C virus non-structural; E=0.69 PF01078; Magnesium chelatase, subunit Chl; E=8.1e-11.
       0.603
RB11914
Best DB hits: BLAST: pir:A75012; conserved hypothetical protein PAB1277 - Pyrococcus; E=2e-04 pir:S75346; hypothetical protein slr2013 - Synechocystis sp. (strain; E=0.001 pir:H71125; hypothetical protein PH0774 - Pyrococcus horikoshii; E=0.014 COG: PAB1277; COG1721 Uncharacterized ACR; E=2e-05 PFAM: PF01882; Protein of unknown function DUF58; E=2e-08.
       0.603
RB11916
Conserved hypothetical protein-putative protease; PMID: 99009353 PMID: 10086841 best DB hits: BLAST: pir:F70464; hypothetical protein aq_1912 - Aquifex aeolicus -----; E=1e-13 ddbj:BAB04325.1; (AP001509) BH0606~unknown conserved protein; E=4e-10 pir:F83287; hypothetical protein PA2873 [imported] - Pseudomonas; E=3e-07 COG: aq_1912; COG1305 Transglutaminase-like enzymes, putative cysteine; E=1e-14 PFAM: PF01841; Transglutaminase-like superfam; E=7e-11.
       0.603
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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