Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
RB11920Conserved hypothetical protein-putative Zn-dependent protease; PMID: 10086841 best DB hits: BLAST: ddbj:BAB04716.1; (AP001510) BH0997~unknown conserved protein; E=2e-44 ddbj:BAB05396.1; (AP001512) BH1677~unknown conserved protein; E=2e-41 pir:F70011; hypothetical protein yugP - Bacillus subtilis -----; E=8e-39 COG: BH0997; COG2738 Predicted Zn-dependent protease; E=2e-45. (249 aa)    
Predicted Functional Partners:
RB11918
Hypothetical protein; Best DB hits: BLAST: pir:E81162; conserved hypothetical protein NMB0742 [imported] -; E=0.034 pir:B81942; hypothetical protein NMA0955 [imported] - Neisseria; E=0.034 gb:AAG23848.1; (AF129396) unknown [Pseudomonas resinovorans]; E=0.11.
       0.773
ilvD
Dihydroxy-acid dehydratase; PMID: 8325851 PMID: 7771772 best DB hits: BLAST: swissprot:P77596; YAGF_ECOLI HYPOTHETICAL 69.4 KD PROTEIN IN; E=0.0 swissprot:P39358; YJHG_ECOLI HYPOTHETICAL 70.0 KD PROTEIN IN; E=0.0 pir:S56522; hypothetical protein f655 - Escherichia coli -----; E=0.0 COG: yagF; COG0129 Dihydroxyacid dehydratase/phosphogluconate dehydratase; E=0.0 MJ1276; COG0129 Dihydroxyacid dehydratase/phosphogluconate; E=5e-48 ilvD; COG0129 Dihydroxyacid dehydratase/phosphogluconate dehydratase; E=2e-34 PFAM: PF00920; Dehydratase family; E=3.6e-208; Belongs to the IlvD/Edd family.
       0.773
RB11922
Conserved hypothetical protein-putative membrane protein; PMID: 10086841 best DB hits: BLAST: ddbj:BAB06330.1; (AP001516) BH2611~unknown conserved protein; E=4e-08 pir:F69930; conserved hypothetical protein yozB - Bacillus subtilis; E=1e-07 swissprot:Q04453; YCT1_BACFI HYPOTHETICAL 21.0 KD PROTEIN IN CTAF; E=8e-07 COG: BH2611; COG2322 Predicted membrane protein; E=4e-09.
 
     0.543
RB11923
Conserved hypothetical protein-putative SCO1/SenC; PMID: 1944230 PMID: 7592491 best DB hits: BLAST: ddbj:BAB07054.1; (AP001518) BH3335~unknown conserved protein; E=6e-19 swissprot:P54178; YPMQ_BACSU HYPOTHETICAL 21.6 KDA PROTEIN IN ILVA; E=1e-12 ddbj:BAB06623.1; (AP001517) BH2904~unknown conserved protein; E=2e-12 COG: BH3335; COG1999 Uncharacterized protein SCO1/SenC/PrrC, involved in; E=6e-20 BH2868; COG0526 Thiol-disulfide isomerase and thioredoxins; E=1e-04 DR1886; COG1999 Uncharacterized protein SCO1/SenC/PrrC, involved in; E=2e-04 PFAM: PF02630; SCO1/SenC; E=1.7e-14.
       0.484
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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