STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RB12108Probable response regulatory protein (atoC); PMID: 9665876 PMID: 8346225 best DB hits: BLAST: ddbj:BAB06667.1; (AP001517) two-component response regulator in; E=2e-87 pir:F71315; probable response regulatory protein (atoC) - syphilis; E=1e-85 gb:AAF33506.1; (AF170176) Salmonella typhimurium transcriptional; E=5e-83 COG: BH2948; COG2204 AAA superfamily ATPases with N-terminal receiver; E=2e-88 aq_218_2; COG1221 NtrC family transcriptional regulators, ATPase; E=1e-66 CT468; COG2204 AAA superfamily ATPases with N-terminal receiver; E=5e-66 PFAM: PF00072; Response regulator receiver doma; [...] (485 aa)    
Predicted Functional Partners:
RB6491
RNA polymerase subunit sigma-54; PMID: 2203540 best DB hits: BLAST: gb:AAC82369.1; (AF061965) RNA polymerase subunit sigma-54; E=1e-121 gb:AAG58336.1; AE005548_7 (AE005548) RNA polymerase, sigma(54 or; E=7e-59 swissprot:P24255; RP54_ECOLI RNA POLYMERASE SIGMA-54 FACTOR; E=2e-58 COG: rpoN; COG1508 DNA-directed RNA polymerase specialized sigma; E=2e-59 PFAM: PF00356; Bacterial regulatory proteins; E=0.018 PF00309; Sigma-54 factors family; E=4e-155.
 
   
 0.777
hydG
Probable hydrogenase regulatory protein HydG; PMID: 1756170 best DB hits: BLAST: gb:AAF33506.1; (AF170176) Salmonella typhimurium transcriptional; E=3e-12 gb:AAG59807.1; AF305914_2 (AF305914) HydG [Klebsiella oxytoca]; E=3e-12 swissprot:P25852; HYDG_SALTY TRANSCRIPTIONAL REGULATORY PROTEIN; E=4e-12 COG: hydG; COG2204 AAA superfamily ATPases with N-terminal receiver; E=2e-12 BS_yqiR_2; COG1221 NtrC family transcriptional regulators, ATPase; E=4e-08 glnG; COG2204 AAA superfamily ATPases with N-terminal receiver; E=1e-07 PFAM: PF00158; Sigma-54 interaction domain; E=2e-05.
  
     0.739
RB10924
Probable sensor/response regulator hybrid; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
  
 
 0.621
RB4511
Sensory transduction histidine kinase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
  
 
 0.621
pepA
Cytosol aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.
       0.608
RB12110
Hypothetical protein.
       0.509
ntrB
Probable nitrogen regulation protein ntrB; PMID: 7553451 best DB hits: BLAST: pir:A82630; two-component system, sensor protein XF1849 [imported] -; E=1e-11 pir:S35265; ntrB protein - Azospirillum brasilense ----- embl:; E=1e-11 swissprot:P45670; NTRB_AZOBR NITROGEN REGULATION PROTEIN NTRB; E=3e-11 COG: XF1849; COG0642 Sensory transduction histidine kinases; E=1e-12 PFAM: PF00672; HAMP domain; E=9.9e-11 PF00512; His Kinase A (phosphoacceptor) doma; E=0.00015 PF02518; Histidine kinase-, DNA gyrase B-, p; E=4.8e-20.
  
   0.448
atoS-2
Sensor protein atoS; PMID: 8346225 best DB hits: BLAST: swissprot:Q06067; ATOS_ECOLI SENSOR PROTEIN ATOS ----- pir:; E=1e-26 gb:AAF33505.1; (AF170176) Salmonella typhimurium sensor protein; E=3e-25 gb:AAG59806.1; AF305914_1 (AF305914) HydH [Klebsiella oxytoca]; E=1e-24 COG: atoS_3; COG0642 Sensory transduction histidine kinases; E=1e-27 PFAM: PF00072; Response regulator receiver doma; E=2.2e-12 PF00989; PAS domain; E=1.6e-06 PF00785; PAC motif; E=0.00084.
 
 
 
 0.409
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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