Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
RB12183Conserved hypothetical protein; PMID: 10984043 best DB hits: BLAST: pir:F82960; hypothetical protein PA5487 [imported] - Pseudomonas; E=8e-27 pir:A71678; probable response regulatory protein RP237 - Rickettsia; E=7e-22 pir:C83247; hypothetical protein PA3177 [imported] - Pseudomonas; E=2e-21 COG: PA5487; COG2199 Diguanylate cyclase/phosphodiesterase domain 1; E=8e-28 PFAM: PF00990; GGDEF domain; E=2.8e-45. (585 aa)    
Predicted Functional Partners:
RB12766
PMID: 11557134 best DB hits: BLAST: pir:C82181; conserved hypothetical protein VC1592 [imported] -; E=2e-15 pir:G70332; conserved hypothetical protein aq_367 - Aquifex aeolicus; E=6e-15 pir:D83238; hypothetical protein PA3258 [imported] - Pseudomonas; E=2e-13 COG: VC1592; COG2200 Diguanylate cyclase/phosphodiesterase domain 2 (EAL); E=1e-16 aq_367_3; COG2200 Diguanylate cyclase/phosphodiesterase domain 2; E=6e-16 VC1641; COG2200 Diguanylate cyclase/phosphodiesterase domain 2 (EAL); E=2e-09 PFAM: PF00498; FHA domain; E=6.6e-15 PF00563; Domain of unknown function 2; E=3.1e-07.
 
  
 0.863
RB3251
Conserved hypothetical protein; PMID: 8905231 best DB hits: BLAST: pir:S76102; hypothetical protein slr0359 - Synechocystis sp. (strain; E=3e-99 pir:S76238; hypothetical protein sll0267 - Synechocystis sp. (strain; E=2e-89 pir:S77565; hypothetical protein slr2077 - Synechocystis sp. (strain; E=5e-88 COG: PA0575_4; COG2200 Diguanylate cyclase/phosphodiesterase domain 2; E=1e-59 PFAM: PF00900; Ribosomal family S4e; E=0.72 PF00072; Response regulator receiver dom; E=3.8e-29 PF00785; PAC motif; E=0.054.
 
 
0.771
RB1009
Response regulator; PMID: 11123673 best DB hits: BLAST: pir:A75484; conserved hypothetical protein - Deinococcus radiodurans; E=2e-24 pir:D72252; conserved hypothetical protein - Thermotoga maritima; E=1e-23 embl:CAB89843.1; (AJ251547) response regulator [Xanthomonas; E=2e-23 COG: DR0719; COG2206 HD-GYP domain; E=2e-25 PFAM: PF01966; HD domain; E=7.2e-08.
  
 
 0.755
RB1759
PMID: 10567266 best DB hits: BLAST: pir:E72220; conserved hypothetical protein - Thermotoga maritima; E=3e-39 pir:A75484; conserved hypothetical protein - Deinococcus radiodurans; E=1e-37 embl:CAB94603.1; (AL359214) putative integral membrane protein; E=2e-35 COG: DR0719; COG2206 HD-GYP domain; E=1e-38 PFAM: PF01590; GAF domain; E=0.4 PF01966; HD domain; E=1.8e-15.
  
 
 0.752
RB10065
Conserved hypothetical protein-putative phosphohydrolase involved in signal transduction; Best DB hits: BLAST: ddbj:BAA82692.1; (AB013492) ORF14 [Bacillus halodurans] -----; E=4e-20 pir:D83132; hypothetical protein PA4108 [imported] - Pseudomonas; E=4e-17 pir:E71268; conserved hypothetical protein TP0912 - syphilis; E=4e-15 COG: BH0008; COG2206 HD-GYP domain; E=4e-21.
  
 
 0.726
RB10488
PMID: 20572072 best DB hits: BLAST: pir:S75136; sensory transduction histidine kinase slr2104 -; E=3e-67 pir:E83443; probable sensorresponse regulator hybrid PA1611; E=2e-64 pir:H82211; sensory box sensor histidine kinaseresponse regulator; E=8e-61 COG: VC1349_2; COG0642 Sensory transduction histidine kinases; E=7e-62 PFAM: PF00785; PAC motif; E=0.00076 PF00512; His Kinase A (phosphoacceptor) d; E=1.6e-28 PF02518; Histidine kinase-, DNA gyrase B-; E=1.6e-42.
 
 
 0.721
RB3373
PMID: 9098081 best DB hits: BLAST: pir:T28655; receptor-like histidine kinase BpdS - Rhodococcus sp; E=1e-60 pir:T30898; receptor-like histidine kinase - Rhodococcus erythropolis; E=1e-60 pir:S75136; sensory transduction histidine kinase slr2104 -; E=9e-58 COG: VC1349_2; COG0642 Sensory transduction histidine kinases; E=1e-41 PFAM: PF00069; Protein kinase domain; E=8.1e-08 PF00515; TPR Domain; E=0.026 PF00512; His Kinase A (phosphoacceptor); E=1.4e-21.
 
  
 0.709
RB161
Response regulator; PMID: 7699720 best DB hits: BLAST: pir:G82211; response regulator VC1348 [imported] - Vibrio cholerae; E=4e-59 embl:CAB89843.1; (AJ251547) response regulator [Xanthomonas; E=2e-56 pir:S75132; sensory transduction system regulatory protein slr2100 -; E=1e-55 COG: VC1348_2; COG2206 HD-GYP domain; E=1e-42 PFAM: PF00072; Response regulator receiver doma; E=1.1e-29 PF01966; HD domain; E=0.003.
  
  
 0.691
RB13175
PMID: 2201868 best DB hits: BLAST: pir:S75136; sensory transduction histidine kinase slr2104 -; E=2e-67 pir:S75142; sensory transduction histidine kinase slr1759 -; E=2e-55 embl:CAA65047.1; (X95731) putative sensor kinase [Synechocystis; E=3e-55 COG: VC1349_2; COG0642 Sensory transduction histidine kinases; E=1e-50 PFAM: PF00989; PAS domain; E=0.011 PF00785; PAC motif; E=0.075 PF00989; PAS domain; E=0.46.
 
 
 0.627
RB159
PMID: 11406410 best DB hits: BLAST: pir:S75136; sensory transduction histidine kinase slr2104 -; E=2e-69 pir:S75130; sensory transduction histidine kinase slr2098 -; E=4e-63 pir:E83443; probable sensorresponse regulator hybrid PA1611; E=8e-62 COG: VC1349_2; COG0642 Sensory transduction histidine kinases; E=2e-53 PFAM: PF00989; PAS domain; E=5.9e-05 PF00512; His Kinase A (phosphoacceptor); E=4.2e-24 PF02518; Histidine kinase-, DNA gyrase B; E=4.1e-43.
 
  
 0.611
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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