STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dpp4Dipeptidyl peptidase IV; PMID: 7793970 best DB hits: BLAST: pir:S66261; X-Pro dipeptidyl-peptidase (EC 3.4.14.11) -; E=6e-59 ddbj:BAA28265.1; (AB008194) DPP IV [Porphyromonas gingivalis]; E=2e-54 gb:AAC46184.1; (AF026511) dipeptidyl peptidase IV [Porphyromonas; E=7e-54 COG: YHR028c; COG1506 Dipeptidyl aminopeptidases/acylaminoacyl-peptidases; E=2e-30 BH0879; COG2267 Lysophospholipase; E=0.002 PH0863; COG1506 Dipeptidyl aminopeptidases/acylaminoacyl-peptidases; E=0.002 PFAM: PF00930; Dipeptidyl peptidase IV (DPP IV); E=5.3e-44 PF00326; Prolyl oligopeptidase family; E=0.84. (834 aa)    
Predicted Functional Partners:
RB1230
Hypothetical protein.
       0.773
lpd
Dihydrolipoamide dehydrogenase; PMID: 6352260 PMID: 2211531 best DB hits: BLAST: pir:A82753; dihydrolipoamide dehydrogenase XF0868 [imported] -; E=1e-102 swissprot:O50286; DLDH_VIBPA DIHYDROLIPOAMIDE DEHYDROGENASE (E3; E=1e-102 swissprot:P00391; DLDH_ECOLI DIHYDROLIPOAMIDE DEHYDROGENASE (E3; E=1e-101 COG: XF0868_2; COG1249 Dihydrolipoamide dehydrogenase/glutathione; E=1e-103 PFAM: PF02032; Phytoene dehydrogenase related; E=0.00021 PF00070; Pyridine nucleotide-disulphide; E=2.6e-75 PF02852; Pyridine nucleotide-disulphide; E=8.6e-41.
       0.732
ctrB
Phytoene synthase-related protein; PMID: 20175755 PMID: 1537409 best DB hits: BLAST: pir:H81074; phytoene synthase-related protein NMB1521 [imported] -; E=6e-38 pir:D81868; probable transferase NMA1721 [imported] - Neisseria; E=2e-37 pir:T35399; probable phytoene synthase - Streptomyces coelicolor; E=2e-25 COG: NMB1521; COG1562 Phytoene/squalene synthetase; E=5e-39 PFAM: PF00494; Squalene/phytoene synthase; E=2.8e-23.
      
 0.655
RB4928
Probable aminopeptidase; PMID: 7934828 PMID: 1806041 PMID: 8665903 PMID: 2503378 best DB hits: BLAST: pir:G82759; hypothetical protein XF0820 [imported] - Xylella; E=5e-18 ddbj:BAA31158.1; (AB015725) aminopeptidase [Aeromonas caviae]; E=5e-11 ddbj:BAB07580.1; (AP001520) aminopeptidase [Bacillus halodurans]; E=1e-10 COG: XF0820; COG2234 Predicted aminopeptidases; E=5e-19 PFAM: PF02225; PA domain; E=0.0063 PF00595; PDZ domain (Also known as DHR o; E=1.1e-07.
  
    0.652
RB7173
Polyprenyl synthase; PMID: 2198286 best DB hits: BLAST: gb:AAD47627.1; (AF153713) octylprenyl diphosphate synthase-like; E=6e-40 pir:C83075; octaprenyl-diphosphate synthase PA4569 [imported] -; E=8e-40 ddbj:BAA22867.1; (AB001997) solanesyl diphosphate synthase; E=7e-37 COG: PA4569; COG0142 Geranylgeranyl pyrophosphate synthase; E=7e-41 PFAM: PF00348; Polyprenyl synthetase; E=1.4e-49; Belongs to the FPP/GGPP synthase family.
      
 0.639
crtB
Probable phytoene synthase; PMID: 1537409 best DB hits: BLAST: pir:T35400; probable phytoene synthase - Streptomyces coelicolor; E=5e-25 pir:A81118; phytoene synthase, probable NMB1130, NMB1168 [imported]; E=3e-21 swissprot:P37269; CRTB_SYNP7 PHYTOENE SYNTHASE ----- pir:; E=5e-21 COG: NMB1130; COG1562 Phytoene/squalene synthetase; E=3e-22 PFAM: PF00494; Squalene/phytoene synthase; E=0.0026.
      
 0.610
araC-3
Best DB hits: BLAST: pir:T35901; probable araC family transcription regulator -; E=1e-17 swissprot:Q03320; ARAL_STRAT PUTATIVE ARAC-LIKE TRANSCRIPTION; E=2e-16 swissprot:P35319; ARAL_STRLI PUTATIVE ARAC-LIKE TRANSCRIPTION; E=2e-15 COG: ykgD; COG2207 AraC-type DNA-binding domain-containing proteins; E=2e-12 VCA1018_1; COG2169 Adenosine deaminase; E=3e-05 VCA1074; COG2207 AraC-type DNA-binding domain-containing proteins; E=3e-05 PFAM: PF00440; Bacterial regulatory proteins, tetR; E=0.37 PF00165; Bacterial regulatory helix-turn-heli; E=3.5e-25 PF01047; MarR family; E=0.25.
      
 0.607
RB101
PMID: 2691504 best DB hits: BLAST: pir:H75007; probable acylaminoacyl-peptidase (EC 3.4.19.1) PAB1300; E=6e-18 pir:G82543; conserved hypothetical protein XF2551 [imported] - Xylella; E=1e-16 pir:C71137; hypothetical protein PH0863 - Pyrococcus horikoshii; E=7e-16 COG: PAB1300; COG1506 Dipeptidyl aminopeptidases/acylaminoacyl-peptidases; E=5e-19 VNG2302G; COG1506 Dipeptidyl; E=2e-08 APE1832; COG1506 Dipeptidyl aminopeptidases/acylaminoacyl-peptidases; E=3e-08 PFAM: PF01748; Domain of unknown function DUF3; E=0.37 PF00326; Prolyl oligopeptidase family; E=0.042.
  
     0.589
RB981
Conserved hypothetical protein-putative imidazolonepropionase or related amidohydrolase; PMID: 10192928 best DB hits: BLAST: ddbj:BAB06727.1; (AP001517) BH3008~unknown conserved protein; E=1e-19 pir:G72219; conserved hypothetical protein - Thermotoga maritima; E=3e-16 pir:G71130; hypothetical protein PH0812 - Pyrococcus horikoshii; E=2e-12 COG: BH3008; COG1228 Imidazolonepropionase and related amidohydrolases; E=1e-20 PFAM: PF01311; Bacterial export proteins, famil; E=0.13 PF02612; N-acetylglucosamine-6-phosphate; E=0.17.
 
     0.587
nagA-3
Probable N-acetylglucosamine-6-phosphate deacetylase; PMID: 9301118 best DB hits: BLAST: pir:G72219; conserved hypothetical protein - Thermotoga maritima; E=1e-40 ddbj:BAB06727.1; (AP001517) BH3008~unknown conserved protein; E=2e-36 pir:H71130; hypothetical protein PH0813 - Pyrococcus horikoshii; E=3e-26 COG: TM1723; COG1228 Imidazolonepropionase and related amidohydrolases; E=1e-41 BH0421; COG1820 N-acetylglucosamine-6-phosphate deacetylase; E=1e-04 VC1205; COG1228 Imidazolonepropionase and related amidohydrolases; E=3e-04 PFAM: PF02612; N-acetylglucosamine-6-phosphat; E=0.073 PF01979 [...]
 
     0.528
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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