STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RB12279Small-conductance mechanosensitive channel; PMID: 11296222 best DB hits: BLAST: pir:S76700; hypothetical protein - Synechocystis sp. (strain PCC; E=1e-41 pir:F75546; conserved hypothetical protein - Deinococcus radiodurans; E=3e-09 gb:AAG19543.1; (AE005044) Vng1164c [Halobacterium sp. NRC-1]; E=9e-08 COG: slr0109; COG0668 Small-conductance mechanosensitive channel; E=9e-43 PA5022; COG3264 Small-conductance mechanosensitive channel; E=2e-05 TP0822; COG0668 Small-conductance mechanosensitive channel; E=3e-05 PFAM: PF00924; Uncharacterized protein family UPF00; E=2.1e-24. (337 aa)    
Predicted Functional Partners:
RB12281
Hypothetical protein.
       0.780
RB10255
Conserved hypothetical protein-putative mechanosensitive ion channel; PMID: 10952301 best DB hits: BLAST: pir:A82318; conserved hypothetical protein VC0480 [imported] -; E=1e-37 swissprot:O52401; YGGB_EDWIC HYPOTHETICAL 30.6 KDA PROTEIN IN; E=2e-36 pir:B83096; conserved hypothetical protein PA4394 [imported] -; E=2e-31 COG: VC0480; COG0668 Small-conductance mechanosensitive channel; E=1e-38 HI0195.1; COG3264 Small-conductance mechanosensitive channel; E=2e-12 APE1441; COG0668 Small-conductance mechanosensitive channel; E=4e-12 PFAM: PF00924; Uncharacterized protein family UPF00; E=2.7e-52.
  
   
 0.619
RB2200
Small conductance mechanosensitive ion channel; PMID: 10910347 best DB hits: BLAST: pir:C82162; conserved hypothetical protein VC1751 [imported] -; E=3e-56 swissprot:O52401; YGGB_EDWIC HYPOTHETICAL 30.6 KDA PROTEIN IN; E=4e-41 pir:A82318; conserved hypothetical protein VC0480 [imported] -; E=5e-40 COG: VC1751; COG0668 Small-conductance mechanosensitive channel; E=3e-57 PFAM: PF00924; Uncharacterized protein family UPF00; E=2.9e-71.
  
     0.598
RB4461
Conserved hypothetical protein; PMID: 9679194 best DB hits: BLAST: pir:H82702; small conductance mechanosensitive ion channel XF1258; E=2e-17 pir:E71140; hypothetical protein PH0336 - Pyrococcus horikoshii; E=1e-15 pir:B83096; conserved hypothetical protein PA4394 [imported] -; E=2e-15 COG: XF1258; COG0668 Small-conductance mechanosensitive channel; E=2e-18 HI0195.1; COG3264 Small-conductance mechanosensitive channel; E=1e-09 PFAM: PF00924; Uncharacterized protein family UPF00; E=6.2e-44.
 
  
 0.553
RB10721
Conserved hypothetical protein-putative transmembrane channel protein; Best DB hits: BLAST: pir:S56387; hypothetical protein f1107 - Escherichia coli -----; E=9e-35 swissprot:P39285; YJEP_ECOLI HYPOTHETICAL 123.8 KD PROTEIN IN; E=2e-34 gb:AAG59358.1; AE005649_3 (AE005649) putative periplasmic binding; E=2e-34 COG: yjeP; COG3264 Small-conductance mechanosensitive channel; E=2e-35 PA1408_2; COG0668 Small-conductance mechanosensitive channel; E=2e-15 PFAM: PF00924; Uncharacterized protein famil; E=2.9e-36.
 
  
 0.538
RB12282
Predicted permease; Best DB hits: BLAST: embl:CAB83202.1; (AJ277117) putative membrane protein; E=4e-35 pir:H82825; transport protein XF0281 [imported] - Xylella fastidiosa; E=8e-26 swissprot:O34472; YRRI_BACSU HYPOTHETICAL 39.6 KDA PROTEIN IN; E=2e-13 COG: XF0281; COG0628 Predicted permease; E=7e-27 PFAM: PF01594; Domain of unknown function DUF20; E=0.3.
  
    0.494
kefA
Potassium efflux system KefA; PMID: 10202137 best DB hits: BLAST: swissprot:P77338; KEFA_ECOLI POTASSIUM EFFLUX SYSTEM KEFA (AEFA; E=3e-55 gb:AAK02442.1; (AE006072) unknown [Pasteurella multocida]; E=1e-52 swissprot:Q57362; YJEP_HAEIN PROTEIN HI0195.1 PRECURSOR -----; E=9e-49 COG: aefA; COG3264 Small-conductance mechanosensitive channel; E=3e-56 slr0510_1; COG0668 Small-conductance mechanosensitive channel; E=1e-18 PFAM: PF00924; Uncharacterized protein family UPF0; E=1.4e-66.
 
  
 0.463
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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