Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RB12285Conserved hypothetical protein-putative dimethyladenosine transferase (rRNA methylation); PMID: 10484179 best DB hits: BLAST: ddbj:BAB05775.1; (AP001514) BH2056~unknown conserved protein in; E=1e-12 pir:T45542; hypothetical protein [imported] - Klebsiella pneumoniae; E=1e-08 gb:AAG10237.1; AF201699_2 (AF201699) phospholipid; E=6e-05 COG: BH2056; COG0030 Dimethyladenosine transferase (rRNA methylation); E=1e-13 Rv2622; COG0500 SAM-dependent methyltransferases; E=6e-04. (224 aa)    
Predicted Functional Partners:
RB12283
Hypothetical protein.
       0.746
RB12282
Predicted permease; Best DB hits: BLAST: embl:CAB83202.1; (AJ277117) putative membrane protein; E=4e-35 pir:H82825; transport protein XF0281 [imported] - Xylella fastidiosa; E=8e-26 swissprot:O34472; YRRI_BACSU HYPOTHETICAL 39.6 KDA PROTEIN IN; E=2e-13 COG: XF0281; COG0628 Predicted permease; E=7e-27 PFAM: PF01594; Domain of unknown function DUF20; E=0.3.
 
     0.600
pss
Probable CDP-diacylglycerol--serine O-phosphatidyltransferase; PMID: 2830250 best DB hits: BLAST: pir:F71678; CDPdiacylglycerol--serine O-phosphatidyltransferase (EC; E=1e-12 pir:G82804; phosphatidyltransferase XF0442 [imported] - Xylella; E=2e-12 pir:T47268; phosphatidylserine synthase [imported] - Helicobacter; E=3e-12 COG: RP242; COG1183 Phosphatidylserine synthase; E=1e-13 Rv2612c; COG0558 Phosphatidylglycerophosphate synthase; E=1e-05 AF2044; COG1183 Phosphatidylserine synthase; E=1e-05 PFAM: PF01066; CDP-alcohol phosphatidyltrans; E=1.1e-08; Belongs to the CDP-alcohol phosphatidy [...]
 
     0.488
RB11084
PMID: 9384377 best DB hits: BLAST: pir:F69688; response regulator aspartate phosphatase rapC - Bacillus; E=0.79.
  
     0.420
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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