STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RB12310Serine/threonine-protein kinase; PMID: 1835671 PMID: 7768349 best DB hits: BLAST: swissprot:P54744; PKNB_MYCLE PUTATIVE SERINETHREONINE-PROTEIN; E=2e-35 swissprot:P71584; PKNB_MYCTU PUTATIVE SERINETHREONINE-PROTEIN; E=2e-35 pir:T36717; probable serinethreonine protein kinase - Streptomyces; E=1e-32 COG: Rv0014c_1; COG0515 Serine/threonine protein kinases; E=2e-36 PFAM: PF00069; Protein kinase domain; E=8.9e-53. (758 aa)    
Predicted Functional Partners:
RB12313
Similar to extracytoplasmic sigma factor ECF; PMID: 11936079 PMID: 3052291 best DB hits: BLAST: embl:CAB72200.1; (AL138851) putative RNA polymerase sigma factor; E=0.060 PFAM: PF00196; Bacterial regulatory proteins; E=0.59.
 
 
   0.872
RB621
Hypothetical protein-putative sigma factor; PMID: 12024217 best DB hits: BLAST: gb:AAB64901.1; AAB64901 (U33050) Spp41p: Negative regulator of prp; E=0.81 swissprot:P38904; SP41_YEAST SPP41 PROTEIN ----- gb: AAA20494.1; E=0.81.
 
 
   0.748
RB10164
Conserved hypothetical protein-putative sigma factor; PMID: 12024217 best DB hits: BLAST: pir:T02748; hypothetical protein R31180_1 - human ----- gb:; E=0.38.
  
 
   0.740
RB5585
Similar to RNA polymerase sigma-E factor; PMID: 12024217 best DB hits: BLAST: embl:CAB83107.1; (AJ276657) sigma factor 3 [Sinapis alba]; E=0.13 pir:B72234; RNA polymerase sigma-E factor - Thermotoga maritima; E=0.17 pir:S30404; hypothetical protein 3 - Streptomyces clavuligerus; E=0.21 PFAM: PF01046; NodD transcription activator c; E=0.2 PF00140; Sigma-70 factor; E=0.00055 PF00196; Bacterial regulatory proteins,; E=0.043.
  
 
   0.739
RB11990
Best DB hits: PFAM: PF00140; Sigma-70 factor; E=0.0091 PF00196; Bacterial regulatory proteins, l; E=0.0013.
 
 
   0.734
RB3245
Protein phosphatase 1; PMID: 11298281 best DB hits: BLAST: gb:AAF81068.1; AF223364_3 (AF223364) protein phosphatase 1; E=3e-27 pir:E71538; hypothetical protein CT259 - Chlamydia trachomatis; E=5e-26 embl:CAA10712.1; (AJ132604) pppL protein [Lactococcus lactis]; E=2e-25 COG: CT259; COG0631 Protein serine/threonine phosphatases; E=4e-27 PFAM: PF00481; Protein phosphatase 2C; E=1.2e-09.
  
   0.720
Pph1
Probable protein phosphatase 1; PMID: 11298281 best DB hits: BLAST: gb:AAF81068.1; AF223364_3 (AF223364) protein phosphatase 1; E=9e-32 pir:E71538; hypothetical protein CT259 - Chlamydia trachomatis; E=4e-28 pir:H75265; conserved hypothetical protein - Deinococcus radiodurans; E=5e-28 COG: CT259; COG0631 Protein serine/threonine phosphatases; E=4e-29 PFAM: PF00481; Protein phosphatase 2C; E=4.9e-09.
  
   0.720
RB12305
PMID: 10048488 best DB hits: BLAST: ddbj:BAB10826.1; (AB016892) receptor protein kinase-like protein; E=0.011 embl:CAB51834.1; (AJ243961) contains eukaryotic protein kinase; E=0.057 gb:AAG50525.1; AC084221_7 (AC084221) hypothetical protein; E=0.28.
 
     0.517
RB12314
Hypothetical protein.
       0.509
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.