Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RB12337Prolyl endopeptidase; PMID: 8370677 best DB hits: BLAST: pir:B75267; prolyl endopeptidase - Deinococcus radiodurans (strain; E=0.0 gb:AAD34991.1; (AF143951) prolyl endopeptidase [Aeromonas; E=1e-173 gb:AAF02211.1; (AF065429) prolyl endopeptidase [Aeromonas; E=1e-173 COG: DR2503; COG1505 Serine proteases of the peptidase family S9A; E=0.0 PA1304; COG1770 Protease II (serine protease PtrB); E=7e-45 NMB1877; COG1505 Serine proteases of the peptidase family S9A; E=2e-38 PFAM: PF02897; Prolyl oligopeptidase, N-termi; E=2.7e-149 PF00326; Prolyl oligopeptidase family; E=2.6e-40. (759 aa)    
Predicted Functional Partners:
RB12343
Sucrose phosphorylase; PMID: 1368718 best DB hits: BLAST: swissprot:P76041; SUCP_ECOLI PUTATIVE SUCROSE PHOSPHORYLASE; E=1e-123 pir:H64879; probable membrane protein b1309 - Escherichia coli; E=1e-123 ddbj:BAA14878.1; (D90768) Sucrose phosphorylase (EC 2.4.1.7); E=1e-121 COG: ycjM; COG0366 Glycosidases; E=1e-124 PFAM: PF00128; Alpha amylase, catalytic domain; E=0.0025.
  
  
 0.606
RB12342
Hypothetical protein-transmembrane prediction.
  
    0.599
RB12338
Hypothetical protein.
       0.594
RB12340
Hypothetical protein-transmembrane prediction.
       0.594
RB12344
Predicted glycosyltransferase; Best DB hits: BLAST: pir:G72278; hypothetical protein - Thermotoga maritima (strain MSB8); E=5e-43 ddbj:BAA25653.1; (AB005901) deduced glucosyltransferase; E=1e-07 pir:F64500; probable hexosyltransferase (EC 2.4.1.-) MJ1607 -; E=7e-05 COG: TM1230; COG0438 Predicted glycosyltransferases; E=5e-44 PFAM: PF02843; Phosphoribosylglycinamide syn; E=0.45 PF00534; Glycosyl transferases group 1; E=0.018.
       0.590
RB9029
Probable zinc metalloproteinase; PMID: 10571076 best DB hits: BLAST: embl:CAB08809.1; (Z95398) unknown [Mycobacterium leprae]; E=1e-152 pir:C70838; probable zinc metalloproteinase Rv0198c - Mycobacterium; E=1e-150 ddbj:BAA24495.1; (AB010440) PepO [Porphyromonas gingivalis]; E=1e-142 PFAM: PF01447; Thermolysin metallopeptidase, c; E=0.64 PF01431; Peptidase family M13; E=1.3e-88.
  
  
 0.537
RB12347
Similar to hydrolase; PMID: 7826004 best DB hits: BLAST: pir:G75522; hydrolase, CbbYCbbZ/GpH/YieH family - Deinococcus; E=0.045 swissprot:Q94915; REG2_DROME RHYTHMICALLY EXPRESSED GENE 2 PROTEIN; E=0.14 pir:E75169; hypothetical protein PAB2019 - Pyrococcus abyssi (strain; E=0.15 COG: DR0414; COG1011 Predicted hydrolases of the HAD superfamily; E=0.004 PFAM: PF00702; haloacid dehalogenase-like hydrolas; E=2e-07.
  
    0.493
fxsA
Similar to FxsA protein; PMID: 10497016 PMID: 11932238 best DB hits: BLAST: pir:E82044; fxsA protein VC2696 [imported] - Vibrio cholerae (group; E=0.013 ddbj:BAB06881.1; (AP001517) BH3162~unknown conserved protein; E=0.14 pir:C70004; conserved hypothetical protein ytzA - Bacillus subtilis; E=0.84 COG: VC2696; COG3030 Uncharacterized ACR; E=0.001.
       0.488
RB12334
Probable Zn-dependent protease; Best DB hits: BLAST: gb:AAB90905.1; (AE001082) conserved hypothetical protein; E=4e-06 embl:CAB59505.1; (AL132648) hypothetical protein SCI41.35c; E=6e-05 pir:A69209; conserved hypothetical protein MTH816 - Methanobacterium; E=0.001 COG: AF0332_1; COG1994 Zn-dependent proteases; E=6e-06.
       0.475
RB4928
Probable aminopeptidase; PMID: 7934828 PMID: 1806041 PMID: 8665903 PMID: 2503378 best DB hits: BLAST: pir:G82759; hypothetical protein XF0820 [imported] - Xylella; E=5e-18 ddbj:BAA31158.1; (AB015725) aminopeptidase [Aeromonas caviae]; E=5e-11 ddbj:BAB07580.1; (AP001520) aminopeptidase [Bacillus halodurans]; E=1e-10 COG: XF0820; COG2234 Predicted aminopeptidases; E=5e-19 PFAM: PF02225; PA domain; E=0.0063 PF00595; PDZ domain (Also known as DHR o; E=1.1e-07.
  
    0.463
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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