STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ksgADimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. (284 aa)    
Predicted Functional Partners:
rpsI
30S ribosomal protein S9; PMID: 3884974 PMID: 1091515 best DB hits: BLAST: swissprot:P02363; RS9_ECOLI 30S RIBOSOMAL PROTEIN S9 -----; E=1e-22 gb:AAK02605.1; (AE006087) RpS9 [Pasteurella multocida]; E=5e-22 pir:C82308; ribosomal protein S9 VC0571 [imported] - Vibrio cholerae; E=2e-21 COG: rpsI; COG0103 Ribosomal protein S9; E=1e-23 PFAM: PF00380; Ribosomal protein S9/S16; E=7.2e-51; Belongs to the universal ribosomal protein uS9 family.
 
 
 
 0.946
rtcA
RNA 3-terminal phosphate cyclase (RNA-3-phosphate cyclase); Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.
   
   0.945
rpsD
30S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
   
 
 0.929
rspB
Ribosomal protein S2; PMID: 6806564 PMID: 6272196 PMID: 7023985 PMID: 10094780 best DB hits: BLAST: pir:F75386; ribosomal protein S2 - Deinococcus radiodurans (strain; E=9e-52 swissprot:Q9WZM1; RS2_THEMA 30S RIBOSOMAL PROTEIN S2 -----; E=2e-51 pdb:1FJF; B Chain B, Structure Of The Thermus Thermophilus 30s; E=2e-50 COG: DR1513; COG0052 Ribosomal protein S2; E=8e-53 PFAM: PF00318; Ribosomal protein S2; E=1.2e-82; Belongs to the universal ribosomal protein uS2 family.
  
 
 0.924
rpsG
30S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.
  
 
 0.918
rpsE
30S ribosomal protein S5; With S4 and S12 plays an important role in translational accuracy; Belongs to the universal ribosomal protein uS5 family.
  
 
 0.917
rpsL
30S ribosomal protein S12; With S4 and S5 plays an important role in translational accuracy.
   
 
 0.916
rpsJ
30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.
  
 
 0.916
rpsC
30S ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family.
  
 
 0.914
rpsQ
Probable 30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
  
 
 0.914
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.