STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RB12432Arylsulfatase A precursor; PMID: 7910580 best DB hits: BLAST: swissprot:P50428; ARSA_MOUSE ARYLSULFATASE A PRECURSOR (ASA); E=5e-36 gb:AAC27821.1; (AF013158) arylsulfatase [Heliocidaris; E=7e-36 embl:CAA34667.1; (X16679) arylsulfatase [Hemicentrotus; E=1e-35 COG: aslA; COG3119 Arylsulfatase A and related enzymes; E=8e-28 PAB0793; COG2194 Predicted membrane-associated, metal-dependent; E=0.001 VNG1337C; COG3119 Arylsulfatase A and related enzymes; E=0.004 PFAM: PF00884; Sulfatase; E=2.2e-39. (554 aa)    
Predicted Functional Partners:
RB4561
Beta-hexosaminidase; PMID: 8969205 PMID: 10220172 best DB hits: BLAST: pir:B82755; beta-hexosaminidase precursor XF0847 [imported] -; E=2e-35 swissprot:P96155; HEX1_VIBFU BETA-HEXOSAMINIDASE; E=4e-26 pir:A82301; beta-N-acetylhexosaminidase VC0613 [imported] - Vibrio; E=2e-25 PFAM: PF02838; Glycosyl hydrolase family 20,; E=0.00019 PF00728; Glycosyl hydrolase family 20,; E=5.3e-07.
  
 
  0.915
RB12431
Probable sulfatase; PMID: [EscherichiacoliO157:H7] best DB hits: BLAST: gb:AAF32278.1; (AF211192) SULF1 [Drosophila melanogaster]; E=7e-13 gb:AAG58881.1; AE005599_13 (AE005599) putative sulfatase; E=1e-12 gb:AAF55296.1; (AE003712) Sulf1 gene product [Drosophila; E=8e-12 COG: PA0031; COG3119 Arylsulfatase A and related enzymes; E=3e-12 PFAM: PF00884; Sulfatase; E=5.6e-14.
 
    
0.813
RB3353
Sialidase [Precursor]; PMID: 1400240 PMID: 8591030 best DB hits: BLAST: swissprot:Q02834; NANH_MICVI SIALIDASE PRECURSOR (NEURAMINIDASE); E=3e-40 pdb:1EUR; Sialidase ----- pdb: 1EUS Sialidase Complexed; E=3e-40 pdb:1EUU; Sialidase Or Neuraminidase, Large 68kd Form -----; E=3e-40 PFAM: PF02012; BNR repeat; E=0.1.
  
  
  0.752
nanH
Neuraminidase precursor; PMID: 8093075 best DB hits: BLAST: ddbj:BAA05853.1; (D28493) neuraminidase precursor [Bacteroides; E=4e-90 pir:JC2500; exo-alpha-sialidase (EC 3.2.1.18) precursor -; E=8e-89 swissprot:P31206; NANH_BACFR SIALIDASE (NEURAMINIDASE) -----; E=2e-68 PFAM: PF02012; BNR repeat; E=0.038.
  
  
  0.727
glnII
Glutamine synthetase II; PMID: 2575672 PMID: 1357539 best DB hits: BLAST: swissprot:P04772; GLN2_BRAJA GLUTAMINE SYNTHETASE II; E=1e-103 swissprot:Q02154; GLN2_RHILP GLUTAMINE SYNTHETASE II; E=1e-99 swissprot:P45626; GLN2_RHIME GLUTAMINE SYNTHETASE II; E=9e-97 COG: YPR035w; COG0174 Glutamine synthase; E=5e-83 PFAM: PF00120; Glutamine synthetase; E=3.6e-133.
      
 0.618
pepT
Aminopeptidase T; Cleaves the N-terminal amino acid of tripeptides. Belongs to the peptidase M20B family.
      
 0.618
whiG
RNA polymerase sigma factor whiG; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
      
 0.618
flhF
PMID: 1447978 best DB hits: BLAST: pir:B72319; flagellar biosynthesis protein FlhF - Thermotoga; E=9e-32 ddbj:BAB06156.1; (AP001515) flagella-associated protein [Bacillus; E=3e-22 swissprot:Q01960; FLHF_BACSU FLAGELLAR BIOSYNTHESIS PROTEIN FLHF; E=2e-21 COG: TM0907; COG1419 Flagellar GTP-binding protein; E=8e-33 AF0622; COG0541 Signal recognition particle GTPase; E=3e-09 PFAM: PF00005; ABC transporter; E=0.018 PF00931; NB-ARC domain; E=0.2 PF00004; ATPase family associated with va; E=0.13.
      
 0.618
pepT-2
Peptidase, M20A family; PMID: 8978088 best DB hits: BLAST: pir:B82211; peptidase, M20A family VC1343 [imported] - Vibrio; E=1e-34 swissprot:P54542; YQJE_BACSU HYPOTHETICAL 39.7 KD PROTEIN IN; E=2e-32 ddbj:BAB05188.1; (AP001512) BH1469~unknown conserved protein; E=7e-32 COG: VC1343; COG2195 Di- and tripeptidases; E=1e-35 PA5390; COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate; E=5e-07 HI1348; COG2195 Di- and tripeptidases; E=5e-06 PFAM: PF01546; Peptidase family M20/M25/M40; E=6.8e-20.
      
 0.618
rpoE
Probable RNA polymerase sigma-E factor; PMID: 7768826 PMID: 7889934 PMID: 7889935 best DB hits: BLAST: pir:H82073; RNA polymerase sigma-E factor VC2467 [imported] - Vibrio; E=1e-05 swissprot:P44790; RPOE_HAEIN RNA POLYMERASE SIGMA-E FACTOR; E=9e-05 pir:C82583; RNA polymerase sigma-H factor XF2239 [imported] -; E=3e-04 COG: VC2467; COG1595 DNA-directed RNA polymerase specialized sigma; E=1e-06 PFAM: PF00776; Sigma-70 factor (ECF subfamily); E=0.0054 PF00140; Sigma-70 factor; E=2.7e-05.
      
 0.596
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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