Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ogt-2O-GlcNAc transferase; PMID: 9083067 best DB hits: BLAST: gb:AAF55179.1; (AE003708) CG5038 gene product [Drosophila; E=5e-28 swissprot:P56558; OGT1_RAT UDP-N-ACETYLGLUCOSAMINE--PEPTIDE; E=3e-27 gb:AAD38597.1; AF145622_1 (AF145622) BcDNA.GH04245 [Drosophila; E=2e-25 COG: MTH83; COG0457 TPR-repeat-containing proteins; E=2e-20 PFAM: PF00515; TPR Domain; E=6.4e-07. (680 aa)    
Predicted Functional Partners:
mntB
Manganese ABC transporter permease protein; PMID: 7743991 best DB hits: BLAST: pir:E69992; conserved hypothetical protein ytgD - Bacillus subtilis; E=3e-41 ddbj:BAB05109.1; (AP001511) BH1390~unknown conserved protein in; E=2e-32 gb:AAD56938.1; AF180520_3 (AF180520) integral membrane protein; E=3e-28 COG: BS_ytgD; COG1108 ABC-type Mn2+/Zn2+ transport systems, permease; E=3e-42 Rv2788; COG1321 Mn-dependent transcriptional regulator; E=3e-10 BH1395; COG1108 ABC-type Mn2+/Zn2+ transport systems, permease; E=5e-10 PFAM: PF00950; ABC 3 transport family; E=1.1e-17 PF02742; Iron dependent repr [...]
       0.773
mntB-2
PMID: 7743991 best DB hits: BLAST: pir:D69992; ABC transporter (membrane protein) homolog ytgC -; E=8e-45 pir:B71357; probable ABC transporter, permease protein (troC) -; E=5e-22 pir:A72089; integral membrane protein - Chlamydophila pneumoniae; E=4e-21 COG: BS_ytgC; COG1108 ABC-type Mn2+/Zn2+ transport systems, permease; E=8e-46 CPn0347_2; COG1321 Mn-dependent transcriptional regulator; E=2e-07 TM0125; COG1108 ABC-type Mn2+/Zn2+ transport systems, permease; E=3e-07 PFAM: PF00950; ABC 3 transport family; E=1.6e-72 PF02742; Iron dependent repressor, metal; E=1.6e-07.
       0.773
mntA
PMID: 7743991 best DB hits: BLAST: pir:C69992; ABC transporter (ATP-binding protein) homolog ytgB -; E=3e-73 pir:A71357; probable ABC transporter, ATP-binding protein (troB) -; E=1e-70 pir:T45470; ATP-binding ABC transport protein [imported] -; E=9e-58 COG: BS_ytgB; COG1121 ABC-type Mn/Zn transport systems, ATPase component; E=3e-74 BS_yfmF; COG1120 ABC-type cobalamin/Fe3+-siderophores transport; E=8e-24 PH1653; COG1121 ABC-type Mn/Zn transport systems, ATPase component; E=5e-23 PFAM: PF02463; SMC domain N terminal domain; E=0.17 PF00005; ABC transporter; E=7.9e-50.
       0.773
ogt-3
Probable O-linked GlcNAc transferase; PMID: 9083067 best DB hits: COG: BH1262; COG0457 TPR-repeat-containing proteins; E=3e-05 PFAM: PF00533; BRCA1 C Terminus (BRCT) domain; E=7.9e-06 PF00515; TPR Domain; E=0.012.
  
     0.633
RB6671
Conserved hypothetical protein; PMID: 98151343 best DB hits: BLAST: gb:AAF55179.1; (AE003708) CG5038 gene product [Drosophila; E=4e-10 gb:AAF26789.1; AC016829_13 (AC016829) putative O-linked GlcNAc; E=4e-09 ddbj:BAB21885.1; (AB055261) hypothetical protein [Macaca; E=2e-08 COG: MTH72; COG0457 TPR-repeat-containing proteins; E=4e-07 PFAM: PF00515; TPR Domain; E=1.6e-05.
  
     0.586
RB12431
Probable sulfatase; PMID: [EscherichiacoliO157:H7] best DB hits: BLAST: gb:AAF32278.1; (AF211192) SULF1 [Drosophila melanogaster]; E=7e-13 gb:AAG58881.1; AE005599_13 (AE005599) putative sulfatase; E=1e-12 gb:AAF55296.1; (AE003712) Sulf1 gene product [Drosophila; E=8e-12 COG: PA0031; COG3119 Arylsulfatase A and related enzymes; E=3e-12 PFAM: PF00884; Sulfatase; E=5.6e-14.
       0.524
RB12432
Arylsulfatase A precursor; PMID: 7910580 best DB hits: BLAST: swissprot:P50428; ARSA_MOUSE ARYLSULFATASE A PRECURSOR (ASA); E=5e-36 gb:AAC27821.1; (AF013158) arylsulfatase [Heliocidaris; E=7e-36 embl:CAA34667.1; (X16679) arylsulfatase [Hemicentrotus; E=1e-35 COG: aslA; COG3119 Arylsulfatase A and related enzymes; E=8e-28 PAB0793; COG2194 Predicted membrane-associated, metal-dependent; E=0.001 VNG1337C; COG3119 Arylsulfatase A and related enzymes; E=0.004 PFAM: PF00884; Sulfatase; E=2.2e-39.
       0.524
RB12439
Hypothetical protein.
       0.479
RB10541
Similar to O-linked GlcNAc transferase-putativeTPR repeat containing protein; Best DB hits: BLAST: gb:AAF26789.1; AC016829_13 (AC016829) putative O-linked GlcNAc; E=1e-05 swissprot:P56558; OGT1_RAT UDP-N-ACETYLGLUCOSAMINE--PEPTIDE; E=3e-05 gb:AAF31458.1; (AF223393) HRNT1 [Homo sapiens]; E=3e-05 COG: TP0468; COG0457 TPR-repeat-containing proteins; E=7e-04 PFAM: PF00515; TPR Domain; E=0.00012.
  
 
   0.475
RB6395
Probable PKR inhibitor (translation regulation); PMID: 7511204 best DB hits: BLAST: pir:A56534; P58 protein - bovine ----- gb: AAA17795.1; E=2e-08 gb:AAC52592.1; (U28423) p58 [Mus musculus]; E=1e-07 gb:AAC50502.1; (U28424) p58 [Homo sapiens]; E=2e-07 COG: BB0210; COG0457 TPR-repeat-containing proteins; E=2e-04 PFAM: PF00515; TPR Domain; E=0.65.
  
     0.472
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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