STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
mntB-2PMID: 7743991 best DB hits: BLAST: pir:D69992; ABC transporter (membrane protein) homolog ytgC -; E=8e-45 pir:B71357; probable ABC transporter, permease protein (troC) -; E=5e-22 pir:A72089; integral membrane protein - Chlamydophila pneumoniae; E=4e-21 COG: BS_ytgC; COG1108 ABC-type Mn2+/Zn2+ transport systems, permease; E=8e-46 CPn0347_2; COG1321 Mn-dependent transcriptional regulator; E=2e-07 TM0125; COG1108 ABC-type Mn2+/Zn2+ transport systems, permease; E=3e-07 PFAM: PF00950; ABC 3 transport family; E=1.6e-72 PF02742; Iron dependent repressor, metal; E=1.6e-07. (444 aa)    
Predicted Functional Partners:
mntA
PMID: 7743991 best DB hits: BLAST: pir:C69992; ABC transporter (ATP-binding protein) homolog ytgB -; E=3e-73 pir:A71357; probable ABC transporter, ATP-binding protein (troB) -; E=1e-70 pir:T45470; ATP-binding ABC transport protein [imported] -; E=9e-58 COG: BS_ytgB; COG1121 ABC-type Mn/Zn transport systems, ATPase component; E=3e-74 BS_yfmF; COG1120 ABC-type cobalamin/Fe3+-siderophores transport; E=8e-24 PH1653; COG1121 ABC-type Mn/Zn transport systems, ATPase component; E=5e-23 PFAM: PF02463; SMC domain N terminal domain; E=0.17 PF00005; ABC transporter; E=7.9e-50.
 0.999
mtsA
PMID: 7743991 best DB hits: BLAST: pir:B69992; ABC transporter (membrane protein) homolog ytgA -; E=7e-66 pdb:1TOA; A Chain A, Periplasmic Zinc Binding Protein Troa From; E=3e-50 gb:AAA92353.1; (U16363) Tromp1 [Treponema pallidum]; E=3e-50 COG: BS_ytgA; COG0803 ABC-type Mn/Zn transport system, periplasmic; E=7e-67 PFAM: PF01297; Periplasmic solute binding prot; E=3.6e-103; Belongs to the bacterial solute-binding protein 9 family.
 
 0.999
mntB
Manganese ABC transporter permease protein; PMID: 7743991 best DB hits: BLAST: pir:E69992; conserved hypothetical protein ytgD - Bacillus subtilis; E=3e-41 ddbj:BAB05109.1; (AP001511) BH1390~unknown conserved protein in; E=2e-32 gb:AAD56938.1; AF180520_3 (AF180520) integral membrane protein; E=3e-28 COG: BS_ytgD; COG1108 ABC-type Mn2+/Zn2+ transport systems, permease; E=3e-42 Rv2788; COG1321 Mn-dependent transcriptional regulator; E=3e-10 BH1395; COG1108 ABC-type Mn2+/Zn2+ transport systems, permease; E=5e-10 PFAM: PF00950; ABC 3 transport family; E=1.1e-17 PF02742; Iron dependent repr [...]
 
 
0.993
ogt-2
O-GlcNAc transferase; PMID: 9083067 best DB hits: BLAST: gb:AAF55179.1; (AE003708) CG5038 gene product [Drosophila; E=5e-28 swissprot:P56558; OGT1_RAT UDP-N-ACETYLGLUCOSAMINE--PEPTIDE; E=3e-27 gb:AAD38597.1; AF145622_1 (AF145622) BcDNA.GH04245 [Drosophila; E=2e-25 COG: MTH83; COG0457 TPR-repeat-containing proteins; E=2e-20 PFAM: PF00515; TPR Domain; E=6.4e-07.
       0.773
fur
Probable ferric uptake regulation protein Fur; PMID: 7798143 PMID: 2993806 PMID: 2823881 best DB hits: BLAST: swissprot:Q45765; FUR_BORPE FERRIC UPTAKE REGULATION PROTEIN; E=3e-05 swissprot:P06975; FUR_ECOLI FERRIC UPTAKE REGULATION PROTEIN; E=2e-04 gb:AAD01582.1; (AF016035) ferric uptake regulation protein; E=2e-04 COG: fur; COG0735 Fe2+/Zn2+ uptake regulation proteins; E=2e-05 PFAM: PF00403; Heavy-metal-associated domain; E=0.18 PF01475; Ferric uptake regulator family; E=7.4e-05; Belongs to the Fur family.
  
  
 0.736
fur-2
Probable transcription regulator FurR family; PMID: 8083178 PMID: 7590316 PMID: 9765558 best DB hits: BLAST: pir:B70423; transcription regulator FurR family - Aquifex aeolicus; E=2e-15 swissprot:P48796; FUR_CAMJE FERRIC UPTAKE REGULATION PROTEIN; E=7e-13 swissprot:Q51008; FUR_NEIGO FERRIC UPTAKE REGULATION PROTEIN; E=8e-13 COG: aq_1418; COG0735 Fe2+/Zn2+ uptake regulation proteins; E=2e-16 PFAM: PF01475; Ferric uptake regulator family; E=1.5e-22; Belongs to the Fur family.
  
  
 0.736
RB11981
Probable ABC transporter (substrate-binding protein); PMID: 11058132 best DB hits: BLAST: pir:F75516; hypothetical protein - Deinococcus radiodurans (strain; E=8e-44 ddbj:BAB07122.1; (AP001518) ABC transporter (substrate-binding; E=1e-15 gb:AAG18895.1; (AE004992) Vng0316c [Halobacterium sp. NRC-1]; E=1e-15 COG: DR0462; COG0614 ABC-type Fe3+-siderophores transport systems,; E=7e-45 PFAM: PF01497; Periplasmic binding protein; E=0.18.
    
 0.582
RB12431
Probable sulfatase; PMID: [EscherichiacoliO157:H7] best DB hits: BLAST: gb:AAF32278.1; (AF211192) SULF1 [Drosophila melanogaster]; E=7e-13 gb:AAG58881.1; AE005599_13 (AE005599) putative sulfatase; E=1e-12 gb:AAF55296.1; (AE003712) Sulf1 gene product [Drosophila; E=8e-12 COG: PA0031; COG3119 Arylsulfatase A and related enzymes; E=3e-12 PFAM: PF00884; Sulfatase; E=5.6e-14.
       0.524
RB12432
Arylsulfatase A precursor; PMID: 7910580 best DB hits: BLAST: swissprot:P50428; ARSA_MOUSE ARYLSULFATASE A PRECURSOR (ASA); E=5e-36 gb:AAC27821.1; (AF013158) arylsulfatase [Heliocidaris; E=7e-36 embl:CAA34667.1; (X16679) arylsulfatase [Hemicentrotus; E=1e-35 COG: aslA; COG3119 Arylsulfatase A and related enzymes; E=8e-28 PAB0793; COG2194 Predicted membrane-associated, metal-dependent; E=0.001 VNG1337C; COG3119 Arylsulfatase A and related enzymes; E=0.004 PFAM: PF00884; Sulfatase; E=2.2e-39.
       0.524
RB1353
Probable Cytochrome ba3-putative manganese transport protein mntH; PMID: 9428682 best DB hits: BLAST: pir:T44945; hypothetical protein 6 [imported] - Natronobacterium; E=7e-14 swissprot:Q9RTP8; MNTH_DEIRA PROBABLE MANGANESE TRANSPORT PROTEIN; E=7e-08 swissprot:Q9RPF4; MNTH_SALTY MANGANESE TRANSPORT PROTEIN MNTH; E=9e-05 COG: DR1709; COG1914 Mn2+ and Fe2+ transporters of the NRAMP family; E=7e-09 PFAM: PF00122; E1-E2 ATPase; E=0.38 PF01566; Natural resistance-associated ma; E=0.00088.
  
  
 0.516
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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