Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
Experiments
Databases
Textmining
[Homology]
Score
mntAPMID: 7743991 best DB hits: BLAST: pir:C69992; ABC transporter (ATP-binding protein) homolog ytgB -; E=3e-73 pir:A71357; probable ABC transporter, ATP-binding protein (troB) -; E=1e-70 pir:T45470; ATP-binding ABC transport protein [imported] -; E=9e-58 COG: BS_ytgB; COG1121 ABC-type Mn/Zn transport systems, ATPase component; E=3e-74 BS_yfmF; COG1120 ABC-type cobalamin/Fe3+-siderophores transport; E=8e-24 PH1653; COG1121 ABC-type Mn/Zn transport systems, ATPase component; E=5e-23 PFAM: PF02463; SMC domain N terminal domain; E=0.17 PF00005; ABC transporter; E=7.9e-50. (280 aa)    
Predicted Functional Partners:
mntB
Manganese ABC transporter permease protein; PMID: 7743991 best DB hits: BLAST: pir:E69992; conserved hypothetical protein ytgD - Bacillus subtilis; E=3e-41 ddbj:BAB05109.1; (AP001511) BH1390~unknown conserved protein in; E=2e-32 gb:AAD56938.1; AF180520_3 (AF180520) integral membrane protein; E=3e-28 COG: BS_ytgD; COG1108 ABC-type Mn2+/Zn2+ transport systems, permease; E=3e-42 Rv2788; COG1321 Mn-dependent transcriptional regulator; E=3e-10 BH1395; COG1108 ABC-type Mn2+/Zn2+ transport systems, permease; E=5e-10 PFAM: PF00950; ABC 3 transport family; E=1.1e-17 PF02742; Iron dependent repr [...]
 0.999
mntB-2
PMID: 7743991 best DB hits: BLAST: pir:D69992; ABC transporter (membrane protein) homolog ytgC -; E=8e-45 pir:B71357; probable ABC transporter, permease protein (troC) -; E=5e-22 pir:A72089; integral membrane protein - Chlamydophila pneumoniae; E=4e-21 COG: BS_ytgC; COG1108 ABC-type Mn2+/Zn2+ transport systems, permease; E=8e-46 CPn0347_2; COG1321 Mn-dependent transcriptional regulator; E=2e-07 TM0125; COG1108 ABC-type Mn2+/Zn2+ transport systems, permease; E=3e-07 PFAM: PF00950; ABC 3 transport family; E=1.6e-72 PF02742; Iron dependent repressor, metal; E=1.6e-07.
 0.999
mtsA
PMID: 7743991 best DB hits: BLAST: pir:B69992; ABC transporter (membrane protein) homolog ytgA -; E=7e-66 pdb:1TOA; A Chain A, Periplasmic Zinc Binding Protein Troa From; E=3e-50 gb:AAA92353.1; (U16363) Tromp1 [Treponema pallidum]; E=3e-50 COG: BS_ytgA; COG0803 ABC-type Mn/Zn transport system, periplasmic; E=7e-67 PFAM: PF01297; Periplasmic solute binding prot; E=3.6e-103; Belongs to the bacterial solute-binding protein 9 family.
 
 
 0.999
syrD
PMID: 8231810 best DB hits: BLAST: swissprot:P33951; SYRD_PSESY ATP-BINDING PROTEIN SYRD -----; E=8e-65 pir:G83345; pyoverdine biosynthesis protein PvdE PA2397 [imported] -; E=8e-65 pir:S54001; pyoverdine synthetase E - Pseudomonas aeruginosa -----; E=9e-64 COG: PA2397; COG1132 ABC-type multidrug/protein/lipid transport system,; E=8e-66 APE1253; COG1136 ABC-type (unclassified) transport system, ATPase; E=2e-09 XF1081; COG1132 ABC-type multidrug/protein/lipid transport system,; E=2e-07 PFAM: PF00664; ABC transporter transmembrane; E=0.25 PF00470; RecF protein; E=0.13 PF02223; Thymidylat [...]
   
 
  0.901
RB2209
Hypothetical protein-signal peptide and transmembrane prediction.
     
 0.900
RB5826
Conserved hypothetical protein-putative permease; PMID: 8905231 best DB hits: BLAST: pir:S75996; hypothetical protein - Synechocystis sp. (strain PCC; E=2e-05 pir:S77272; hypothetical protein slr0882 - Synechocystis sp. (strain; E=0.023 pir:F72217; conserved hypothetical protein - Thermotoga maritima; E=0.13 COG: sll0496; COG0795 Predicted permeases; E=2e-06.
     
 0.900
ogt-2
O-GlcNAc transferase; PMID: 9083067 best DB hits: BLAST: gb:AAF55179.1; (AE003708) CG5038 gene product [Drosophila; E=5e-28 swissprot:P56558; OGT1_RAT UDP-N-ACETYLGLUCOSAMINE--PEPTIDE; E=3e-27 gb:AAD38597.1; AF145622_1 (AF145622) BcDNA.GH04245 [Drosophila; E=2e-25 COG: MTH83; COG0457 TPR-repeat-containing proteins; E=2e-20 PFAM: PF00515; TPR Domain; E=6.4e-07.
       0.773
RB11981
Probable ABC transporter (substrate-binding protein); PMID: 11058132 best DB hits: BLAST: pir:F75516; hypothetical protein - Deinococcus radiodurans (strain; E=8e-44 ddbj:BAB07122.1; (AP001518) ABC transporter (substrate-binding; E=1e-15 gb:AAG18895.1; (AE004992) Vng0316c [Halobacterium sp. NRC-1]; E=1e-15 COG: DR0462; COG0614 ABC-type Fe3+-siderophores transport systems,; E=7e-45 PFAM: PF01497; Periplasmic binding protein; E=0.18.
    
 0.605
RB12431
Probable sulfatase; PMID: [EscherichiacoliO157:H7] best DB hits: BLAST: gb:AAF32278.1; (AF211192) SULF1 [Drosophila melanogaster]; E=7e-13 gb:AAG58881.1; AE005599_13 (AE005599) putative sulfatase; E=1e-12 gb:AAF55296.1; (AE003712) Sulf1 gene product [Drosophila; E=8e-12 COG: PA0031; COG3119 Arylsulfatase A and related enzymes; E=3e-12 PFAM: PF00884; Sulfatase; E=5.6e-14.
       0.524
RB12432
Arylsulfatase A precursor; PMID: 7910580 best DB hits: BLAST: swissprot:P50428; ARSA_MOUSE ARYLSULFATASE A PRECURSOR (ASA); E=5e-36 gb:AAC27821.1; (AF013158) arylsulfatase [Heliocidaris; E=7e-36 embl:CAA34667.1; (X16679) arylsulfatase [Hemicentrotus; E=1e-35 COG: aslA; COG3119 Arylsulfatase A and related enzymes; E=8e-28 PAB0793; COG2194 Predicted membrane-associated, metal-dependent; E=0.001 VNG1337C; COG3119 Arylsulfatase A and related enzymes; E=0.004 PFAM: PF00884; Sulfatase; E=2.2e-39.
       0.524
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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