Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
mtsAPMID: 7743991 best DB hits: BLAST: pir:B69992; ABC transporter (membrane protein) homolog ytgA -; E=7e-66 pdb:1TOA; A Chain A, Periplasmic Zinc Binding Protein Troa From; E=3e-50 gb:AAA92353.1; (U16363) Tromp1 [Treponema pallidum]; E=3e-50 COG: BS_ytgA; COG0803 ABC-type Mn/Zn transport system, periplasmic; E=7e-67 PFAM: PF01297; Periplasmic solute binding prot; E=3.6e-103; Belongs to the bacterial solute-binding protein 9 family. (366 aa)    
Predicted Functional Partners:
mntB
Manganese ABC transporter permease protein; PMID: 7743991 best DB hits: BLAST: pir:E69992; conserved hypothetical protein ytgD - Bacillus subtilis; E=3e-41 ddbj:BAB05109.1; (AP001511) BH1390~unknown conserved protein in; E=2e-32 gb:AAD56938.1; AF180520_3 (AF180520) integral membrane protein; E=3e-28 COG: BS_ytgD; COG1108 ABC-type Mn2+/Zn2+ transport systems, permease; E=3e-42 Rv2788; COG1321 Mn-dependent transcriptional regulator; E=3e-10 BH1395; COG1108 ABC-type Mn2+/Zn2+ transport systems, permease; E=5e-10 PFAM: PF00950; ABC 3 transport family; E=1.1e-17 PF02742; Iron dependent repr [...]
 
 0.999
mntB-2
PMID: 7743991 best DB hits: BLAST: pir:D69992; ABC transporter (membrane protein) homolog ytgC -; E=8e-45 pir:B71357; probable ABC transporter, permease protein (troC) -; E=5e-22 pir:A72089; integral membrane protein - Chlamydophila pneumoniae; E=4e-21 COG: BS_ytgC; COG1108 ABC-type Mn2+/Zn2+ transport systems, permease; E=8e-46 CPn0347_2; COG1321 Mn-dependent transcriptional regulator; E=2e-07 TM0125; COG1108 ABC-type Mn2+/Zn2+ transport systems, permease; E=3e-07 PFAM: PF00950; ABC 3 transport family; E=1.6e-72 PF02742; Iron dependent repressor, metal; E=1.6e-07.
 
 0.999
mntA
PMID: 7743991 best DB hits: BLAST: pir:C69992; ABC transporter (ATP-binding protein) homolog ytgB -; E=3e-73 pir:A71357; probable ABC transporter, ATP-binding protein (troB) -; E=1e-70 pir:T45470; ATP-binding ABC transport protein [imported] -; E=9e-58 COG: BS_ytgB; COG1121 ABC-type Mn/Zn transport systems, ATPase component; E=3e-74 BS_yfmF; COG1120 ABC-type cobalamin/Fe3+-siderophores transport; E=8e-24 PH1653; COG1121 ABC-type Mn/Zn transport systems, ATPase component; E=5e-23 PFAM: PF02463; SMC domain N terminal domain; E=0.17 PF00005; ABC transporter; E=7.9e-50.
 
 
 0.999
nudF
Probable ADP-ribose pyrophosphatase; PMID: 9694840 best DB hits: BLAST: pir:G69041; mutator MutT protein - Methanobacterium; E=3e-07 swissprot:Q58549; ADPP_METJA ADP-RIBOSE PYROPHOSPHATASE; E=9e-07 embl:CAC12694.1; (AJ272115) hypothetical protein [Thauera; E=2e-06 COG: MTH1315; COG1051 ADP-ribose pyrophosphatase; E=3e-08 BH1893; COG0494 NTP pyrophosphohydrolases including oxidative damage; E=3e-07 VC0331; COG2816 NTP pyrophosphohydrolases containing a Zn-finger,; E=3e-06 PFAM: PF01165; Ribosomal protein S21; E=0.52 PF00293; MutT-like domain; E=1e-25.
       0.773
RB12442
Hypothetical protein-transmembrane prediction.
       0.773
RB12439
Hypothetical protein.
       0.689
rpsN
30 S ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
  
  
 0.665
RB10061
Conserved hypothetical protein-putative containing GTP-binding domain; Best DB hits: BLAST: ddbj:BAB04085.1; (AP001508) BH0366~unknown conserved protein in; E=1e-09 embl:CAC28817.1; (AL513466) conserved hypothetical protein; E=7e-08 pir:D82449; conserved hypothetical protein VCA0527 [imported] -; E=3e-07 COG: BH0366; COG0523 Putative GTPases (G3E family); E=9e-11 sll1079; COG0378 Urease/hydrogenase-associated predicted GTPases; E=0.004 CT418; COG0536 Predicted GTPase; E=0.004 PFAM: PF01443; Viral (Superfamily 1) RNA hel; E=0.53 PF01583; Adenylylsulfate kinase; E=0.7 PF02223; Thymidylat [...]
  
  
 0.612
RB13091
Conserved hypothetical protein-putative cobalamin synthesis protein CobW; PMID: 1655697 best DB hits: BLAST: pir:D82953; conserved hypothetical protein PA5535 [imported] -; E=1e-109 embl:CAC08207.1; (AJ278349) P44k protein [Rhodococcus sp. AJ270]; E=1e-101 pir:B69760; conserved hypothetical protein yciC - Bacillus subtilis; E=1e-98 COG: PA5535; COG0523 Putative GTPases (G3E family); E=1e-110 PFAM: PF01443; Viral (Superfamily 1) RNA hel; E=0.08 PF01495; HypB/UreG nucleotide-binding; E=0.026 PF02492; Cobalamin synthesis protein/P; E=9.1e-107.
  
  
 0.612
RB13094
Conserved hypothetical protein-putative cobalamin synthesis protein CobW; PMID: 1655697 best DB hits: BLAST: swissprot:P33030; YEIR_ECOLI HYPOTHETICAL 36.1 KD PROTEIN IN; E=1e-47 gb:AAG57311.1; AE005450_1 (AE005450) orf, hypothetical protein; E=8e-47 ddbj:BAA15982.1; (D90849) ORF_ID:o369#5; similar to [SwissProt; E=1e-44 COG: yeiR; COG0523 Putative GTPases (G3E family); E=1e-48 PFAM: PF01443; Viral (Superfamily 1) RNA hel; E=0.025 PF02492; Cobalamin synthesis protein/P; E=2.3e-13.
  
  
 0.612
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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