Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RB12541Probable thioredoxin; Best DB hits: BLAST: swissprot:Q10801; DIPZ_MYCTU DIPZ PROTEIN ----- pir: E70923; E=3e-04 pir:E69891; cytochrome c biogenesis protein CycX homolog homolog; E=3e-04 pir:F75549; cytochrome c biogenesis protein CycX homolog DR0189; E=8e-04 COG: BS_yneN; COG0526 Thiol-disulfide isomerase and thioredoxins; E=3e-05 PFAM: PF00085; Thioredoxin; E=0.13. (491 aa)    
Predicted Functional Partners:
RB4417
Cytochrome-c oxidase chain II/c precursor; PMID: 89231697 PMID: 91161592 best DB hits: BLAST: pir:A23711; cytochrome-c oxidase (EC 1.9.3.1) chain IIc precursor -; E=3e-42 swissprot:Q04441; COX2_BACFI CYTOCHROME C OXIDASE POLYPEPTIDE II; E=5e-38 ddbj:BAB06334.1; (AP001516) cytochrome caa3 oxidase (subunit II); E=2e-35 COG: BH2615_1; COG1622 Heme/copper-type cytochrome/quinol oxidases,; E=2e-21 XF1390; COG1622 Heme/copper-type cytochrome/quinol oxidases, subunit; E=1e-14 slr1136; COG1622 Heme/copper-type cytochrome/quinol oxidases,; E=3e-14 PFAM: PF00116; Cytochrome C oxidase subunit II, [...]
   
 
 0.748
ccsA
PMID: 7610180 PMID: 8617725 best DB hits: BLAST: pir:D81040; cytochrome c-type biogenesis protein, probable NMB1803; E=2e-18 pir:B81986; probable membrane protein NMA0660 [imported] - Neisseria; E=2e-18 pir:H71862; probable cytochrome C-type biogenesis protein -; E=7e-17 COG: NMB1803; COG0755 Cytochrome c-type biogenesis protein (heme exporter; E=2e-19 APE2274; COG1138 Cytochrome c biogenesis factor; E=5e-04 NMB1804; COG1333 ResB protein required for cytochrome c biosynthesis; E=0.002 PFAM: PF02590; Uncharacterized ACR, COG1576; E=0.15 PF01578; Cytochrome C assembly protein; E=0.036.
  
  
 0.721
RB8674
Probable thioredoxin; Best DB hits: BLAST: pir:H71366; probable thioredoxin - syphilis spirochete ----- gb:; E=2e-11 gb:AAD00775.1; (U95250) thioredoxin [Treponema pallidum]; E=2e-11 ddbj:BAB06587.1; (AP001516) thioldisulfide interchange protein; E=7e-09 COG: TP0100; COG0526 Thiol-disulfide isomerase and thioredoxins; E=2e-12 XF2174; COG3118 Thioredoxin domain-containing protein; E=7e-07 XF1990; COG0526 Thiol-disulfide isomerase and thioredoxins; E=1e-06 PFAM: PF00085; Thioredoxin; E=0.34.
  
     0.709
ctaC
Cytochrome oxidase subunit II; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).
 
 
 
 0.526
prdX2
Peroxiredoxin 2; PMID: 9115640 best DB hits: BLAST: ref:XP_009063.1; TR00071480_p [Homo sapiens]; E=2e-62 swissprot:Q61171; PDX2_MOUSE PEROXIREDOXIN 2 (THIOREDOXIN; E=3e-62 swissprot:P32119; PDX2_HUMAN PEROXIREDOXIN 2 (THIOREDOXIN; E=4e-62 COG: PA0848; COG0450 Thiol - alkyl hydroperoxide reductases; E=4e-60 PFAM: PF00578; AhpC/TSA family; E=1e-71.
  
 0.490
dsbB
PMID: 7628442 PMID: 7542800 best DB hits: BLAST: pir:H72034; thiol-disulfide interchange protein dsbD [imported] -; E=7e-48 pir:G81503; thiol-disulfide interchange protein DSbD homolog CP1086; E=7e-48 pir:C81653; probable thiol-disulfide interchange protein dsbD; E=8e-47 COG: CPn0786; COG0526 Thiol-disulfide isomerase and thioredoxins; E=6e-49 BH1194; COG0785 Cytochrome c biogenesis protein; E=0.002.
  
 
 0.489
RB12538
Hypothetical protein-signal peptide and transmembrane prediction.
       0.455
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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